Extracellular Matrix Protein 1 Proteins (ECM1)

ECM1 encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. Additionally we are shipping ECM1 Antibodies (67) and ECM1 Kits (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ECM1 1893 Q16610
ECM1 13601 Q61508
ECM1 116662 Q62894
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Top ECM1 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Human Cells Mouse His tag 100 μg 14 to 16 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Human Cells Rat His tag 50 μg 14 to 16 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days
Escherichia coli (E. coli) Human His tag   50 μg 15 to 18 Days
Yeast Yeast His tag   1 mg 60 to 71 Days
Yeast Rat His tag   1 mg 60 to 71 Days
Escherichia coli (E. coli) Human Un-conjugated   100 μg 11 to 18 Days

ECM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) , ,
Rat (Rattus) ,

More Proteins for Extracellular Matrix Protein 1 (ECM1) Interaction Partners

Human Extracellular Matrix Protein 1 (ECM1) interaction partners

  1. Herein we report ocular manifestations of lipoid proteinosis due to a genetic mutation in ECM1 gene.

  2. High ECM1 expression is associated with gastric cancer metastasis.

  3. These observations are consistent with a model in which the loss of Dkk-3 in prostate cancer leads to increased secretion of TGFBI and ECM-1, which have tumor-promoting and tumor-protective roles, respectively

  4. The results showed a significant upregulation of ECM1 and ITGB3, and a significant downregulation for FBLN5 in pelvic organ prolapse patients.

  5. Three patients with homozygous mutations in sixth and seventh exons of the ECM1 gene had a drug-resistant course at the end of long-term follow-up

  6. This proteome analysis indicate that ECM1 is a potential novel plasma protein biomarker for the detection of primary ESCC and evaluation of neoplasms progression

  7. The TT genotype of ECM1 gene rs3737240 SNP significantly increased susceptibility for Ulcerative Colitis and azathioprine use in Ulcerative Colitis patients in a Turkish population.

  8. our work has identified a novel function of ECM1 in inhibiting Th17 cell differentiation in the experimental autoimmune encephalomyelitis model

  9. Our results indicate that although mutation in ECM1gene is responsible for lipoid proteinosis, it is likely that this is not the only gene causing this disease and probably other genes may be involved in the pathogenesis of the LP disease.

  10. ECM1, which displayed a high expression in hepatocellular carcinoma (HCC) specimens, was closely associated with clinicopathologic data and may promote migration and invasion of HCC cells by inducing epithelia-mesenchymal transition.

  11. Cell invasion (matrigel) was reduced only in the Hs578T cells (p < 0.01). Silencing decreased the expression of the prometastatic molecules S100A4 and TGFbetaR2 in both cell lines and CD44 in Hs578T cells. We conclude that ECM1 is a key player in the metastatic process and regulates the actin cytoskeletal architecture of aggressive breast cancer cells at least in part via alterations in S100A4 and Rho A.

  12. Overexpression of miR-486-3p inhibited cell growth and metastasis by targeting ECM1.

  13. For 1q21 loci, we confirmed gene ECM1 as the most plausible gene from this region to be involved in pathogenesis of inflammatory bowel disease

  14. In conclusion, the domain-specific anti-ECM1 MAbs produced in this study should provide a useful tool for investigating ECM1's biological functions, and cellular pathways in which it is involved.

  15. Lipoid proteinosis is a rare autosomal recessive disorder caused by mutations in ECM1, encoding extracellular matrix protein 1, a glycoprotein expressed in many organs and which has important protein-protein interactions in tissue homeostasis

  16. MMP-2 protein and ECM1 gene are useful preoperative markers for defining malignancy in suspicious thyroid nodules

  17. association between beta-catenin and the MUC1 cytoplasmic tail was increased by ECM1

  18. Genetic testing of theECM1 gene showed a homozygous nonsense mutation c.1441C > T (p.Arg481X) in exon 10, confirming the diagnosis of lipoid proteinosis.

  19. Lipoidproteinosis results from a large homozygous deletion of ECM1 gene in a Chinese family.

  20. High extracellular matrix protein-1 expression is associated with the growth, metastasis and angiogenesis of laryngeal carcinoma

Mouse (Murine) Extracellular Matrix Protein 1 (ECM1) interaction partners

  1. data identify ECM1 as a soluble protein to promote TFH cell differentiation and antibody production.

  2. ECM1 seems to be critical for PTHrP action in chondrogenesis, as blockage of ECM1 nearly abolishes PTHrP regulation of chondrocyte hypertrophy, and overexpression of ECM1 rescues disorganized growth plates of PTHrP-null mice; ECM1 and progranulin chondrogenic growth factor constitute an interaction network.

  3. HA accumulation primes the vasculature for atherosclerosis by crosslinking and reorganizing the extracellular matrix (ECM) and by pushing VSMC differentiation towards a less mature phenotype.

  4. Retinoid signaling in the stroma activates expression of Ecm1, which in turn down-regulates Ret expression in the ureteric bud cleft, where bifurcation normally occurs and normal branching progresses.

  5. regulates TH2 cell egress from lymph nodes during allergic airway inflammation

ECM1 Protein Profile

Protein Summary

This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.

Gene names and symbols associated with ECM1

  • extracellular matrix protein 1 (ECM1)
  • extracellular matrix protein 1 (Ecm1)
  • AI663821 protein
  • p85 protein
  • URBWD protein

Protein level used designations for ECM1

secretory component p85 , extracellular matrix protein 1

1893 Homo sapiens
707209 Macaca mulatta
746939 Pan troglodytes
100437948 Pongo abelii
13601 Mus musculus
116662 Rattus norvegicus
608791 Canis lupus familiaris
524222 Bos taurus
100721378 Cavia porcellus
100858704 Gallus gallus
100620701 Sus scrofa
100338579 Oryctolagus cuniculus
101105541 Ovis aries
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