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ECM1 Products

(Extracellular Matrix Protein 1 (ECM1))
Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008].

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Featured ECM1 Categories

ECM1 Antibodies

High quality antibodies with extensive validation data.

ECM1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ECM1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ECM1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (1)
  • (3)
Cat. No. ABIN673071
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (3)
Cat. No. ABIN7267071
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7152334
Quantity 100 μg
Datasheet Datasheet

Recommended ECM1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966619
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962876
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955677
Quantity 96 tests
Datasheet Datasheet

Recommended ECM1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320312
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3079222
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3122981
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ECM1 products

Philley, Kannan, Griffith, Devine, Benwill, Wallace, Brown-Elliott, Thakkar, Taskar, Fox, Alqaid, Bains, Gupta, Dasgupta: "Exosome secretome and mediated signaling in breast cancer patients with nontuberculous mycobacterial disease." in: Oncotarget, Vol. 8, Issue 11, pp. 18070-18081, (2017) (PubMed).

Lee, Nam, Oh, Lim, Kim, Lee, Yu, Ahn, Kim, Noh, Lee, Shin: "Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling." in: Breast cancer research : BCR, Vol. 16, Issue 6, pp. 479, (2015) (PubMed).

Lee, Nam, Oh, Lim, Kim, Shim, Choi, Lee, Yu, Lee, Ahn, Shin: "ECM1 regulates tumor metastasis and CSC-like property through stabilization of β-catenin." in: Oncogene, Vol. 34, Issue 50, pp. 6055-65, (2015) (PubMed).

Gao, Zhang, Ding, Chen, Hu, Jiang, Li, Chen, Wang, Ye, Zhu: "Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cells." in: Cell transplantation, Vol. 22, Issue 10, pp. 1883-900, (2014) (PubMed).

Drabovich, Dimitromanolakis, Saraon, Soosaipillai, Batruch, Mullen, Jarvi, Diamandis: "Differential diagnosis of azoospermia with proteomic biomarkers ECM1 and TEX101 quantified in seminal plasma." in: Science translational medicine, Vol. 5, Issue 212, pp. 212ra160, (2013) (PubMed).

Polosukhin, Cates, Lawson, Zaynagetdinov, Milstone, Massion, Ocak, Ware, Lee, Bowler, Kononov, Randell, Blackwell: "Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease." in: American journal of respiratory and critical care medicine, Vol. 184, Issue 3, pp. 317-27, (2011) (PubMed).

Gologan, Acquafondata, Dhir, Sepulveda: "Polymeric immunoglobulin receptor-negative tumors represent a more aggressive type of adenocarcinomas of distal esophagus and gastroesophageal junction." in: Archives of pathology & laboratory medicine, Vol. 132, Issue 8, pp. 1295-301, (2008) (PubMed).

Tang, Tao, Yun-Liu, Sun, Geng, Jiang: "Immunocytochemical localization of secretory component in Paneth cell secretory granules-rat Paneth cells participate in acquired immunity." in: Journal of molecular histology, Vol. 36, Issue 5, pp. 331-5, (2005) (PubMed).

Fichorova, Anderson: "Differential expression of immunobiological mediators by immortalized human cervical and vaginal epithelial cells." in: Biology of reproduction, Vol. 60, Issue 2, pp. 508-14, (1999) (PubMed).

Fichorova, Rheinwald, Anderson: "Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteins." in: Biology of reproduction, Vol. 57, Issue 4, pp. 847-55, (1997) (PubMed).

Synonyms and alternative names related to ECM1

extracellular matrix protein 1 (ECM1), multimerin 1 (MMRN1), extracellular matrix protein 1 (Ecm1), AI663821, ECM, EMILIN4, GPIa*, MMRN, p85, URBWD

Protein level used designations for ECM1

  • secretory component p85
  • EMILIN-4
  • elastin microfibril interface located protein 4
  • elastin microfibril interfacer 4
  • endothelial cell multimerin
  • glycoprotein Ia*
  • multimerin-1
  • extracellular matrix protein 1
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