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The Fos gene family consists of 4 members FOSL1, and FOSL2. Additionally we are shipping FOSL1 Antibodies (88) and FOSL1 Proteins (10) and many more products for this protein.
Showing 10 out of 18 products:
Mouse (Murine) FOSL1 ELISA Kit - ABIN1053820
Chen, Wang, Chen, Zhang, Shen, Zhang, Chen: Activation of Toll-like receptors by intestinal microflora reduces radiation-induced DNA damage in mice. in Mutation research. Genetic toxicology and environmental mutagenesis 2014
MUC1 (show MUC1 ELISA Kits) enhancement of ERK (show EPHB2 ELISA Kits) activation influences FRA-1 activity to modulate tumor migration, invasion and metastasis in a subset of pancreatic cancer cases
the results indicate that FRA1 promotes cancer growth through AKT (show AKT1 ELISA Kits), and enhances cancer cell migration through JNK/c-Jun, pinpointing FRA1 as a key integrator of JNK (show MAPK8 ELISA Kits) and AKT (show AKT1 ELISA Kits) signaling pathways and a potential therapeutic target for squamous cell carcinoma of the skin and head and neck squamous cell carcinoma.
Study shows that FOSL1 is the main immediate early AP-1 (show JUN ELISA Kits) member induced by melanoma oncogenes; found that FOSL1 is involved in melanoma cell migration as well as cell proliferation and anoikis-independent growth.
a Fra-1-miR (show MLXIP ELISA Kits)-134 axis drives a positive feedback loop that amplifies ERK (show EPHB2 ELISA Kits)/JNK (show MAPK8 ELISA Kits) signaling and reduces chemosensitivity in ovarian cancer cells.
PKCtheta (show PRKCQ ELISA Kits);-induced phosphorylations control the ability of Fra-1 to stimulate gene expression and breast cancer cell migration.
Multivariate analysis identified Fra-1 as an independent prognostic factor. Fra-1 may be involved in the progress of hepatocellular carcinoma and could be a promising molecular candidate in the diagnosis and treatment of hepatocellular carcinoma.
Up-regulation of Fra-1 appeared in retinal ganglion cells following light-induced retina damage.
HGF (show HGF ELISA Kits)-induced FRA1 activation is associated with the fibrosis-dependent development of Hepatocellular Carcinoma.
Our results demonstrate that Fra-1 is an important determinant of the metastatic potential of human colon cancer cells, and that the Fra-1 classifier can be used as a prognostic predictor in colon cancer patients.
Results suggest that Fra-1 is upregulated in lung cancer tissues and functions by affecting the P53 (show TP53 ELISA Kits) signaling pathway.
NF-kappaB (show NFKB1 ELISA Kits) and c-Jun (show JUN ELISA Kits) coregulate lipopolysaccharide-induced Fra-1 transcription.
Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3 (show TRAF3 ELISA Kits)), TIR domain-containing adapter inducing IFN-beta (show IFNB1 ELISA Kits) (TRIF (show RNF138 ELISA Kits)), and Tank-binding kinase 1 (TBK1 (show TBK1 ELISA Kits)) via impairing K63-linked polyubiquitination of TRAF3 (show TRAF3 ELISA Kits) and TRIF (show RNF138 ELISA Kits).
Adipose-derived stromal cells overexpressing Fra-1 effectively protect against osteoarthritis.
Overexpression of Fosl1, which encodes a component of the AP-1 (show JUN ELISA Kits) transcription factor complex, in osteoblasts significantly blocked malleal capillary narrowing.
Fra-1 gene expression is activated in response lipopolysaccharide induced lung-injury in mice.
Data suggest that expression of Fra1 (fos-related antigen 1) in preadipocytes is up-regulated by arachidonic acid (AA) during late stages of adipogenesis; however, in early stage of adipogenesis, AA inhibits adipogenesis via Fra1-dependent mechanism.
Fra-1 plays a key role in promoting chronic CS-induced lung macrophagic inflammation in vivo
we demonstrate that Fra1 negatively controls plasma cell differentiation by repressing Blimp1 (show PRDM1 ELISA Kits) expression.
observations suggest that MyoD (show MYOD1 ELISA Kits) and pRb (show PGR ELISA Kits) work together cooperatively at the level of the intronic enhancer of Fra-1 during terminal cell cycle arrest
findings, based on a definitive genetic mouse model provide fundamental insights into mammary duct maturation and homeostasis and reveal that Scrib (show SCRIB ELISA Kits) loss activates a MAPK (show MAPK1 ELISA Kits)/Fra1 pathway that alters mammary progenitor activity
The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
, fos-related antigen 1
, FOS-like antigen 1