anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) Antibodies

FABP5 encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Additionally we are shipping FABP5 Kits (68) and FABP5 Proteins (29) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FABP5 2171 Q01469
FABP5 16592 Q05816
FABP5 140868 P55053
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Top anti-FABP5 Antibodies at antibodies-online.com

Showing 10 out of 131 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Rabbit Un-conjugated IHC (p), WB Anti-Fatty Acid Binding Protein 5 antibody, IHC(P) IHC(P): Rat Intestine Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- Fatty Acid Binding Protein 5 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti- Fatty Acid Binding Protein 5 antibody, Western blotting All lanes: Anti Fatty Acid Binding Protein 5  at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: HEPG2 Whole Cell Lysate at 40ug Predicted bind size: 15KD Observed bind size: 15KD 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of FABP5 using anti-FABP5 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human Hela whole cell lysates, Lane 2: human A549 whole cell lysates, Lane 3: rat thymus tissue lysates, Lane 4: mouse thymus tissue lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-FABP5 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for FABP5 at approximately 15KD. The expected band size for FABP5 is at 15KD. IHC analysis of FABP5 using anti-FABP5 antibody . FABP5 was detected in paraffin-embedded section of human lung cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml rabbit anti-FABP5 Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rat Un-conjugated CyTOF, FACS, ICC, WB FABP5 in HUVEC Human Cells. FABP5 was detected in immersion fixed HUVEC human umbilical vein endothelial cells using Rat Anti-Human FABP5 Monoclonal Antibody. Detection of Human FABP5/E-FABP by Western Blot. Western blot shows lysates of human heart tissue, human brain (cerebellum) tissue, and human placenta tissue. PVDF membrane was probed with 1 ug/mL of Rat Anti-Human FABP5/E-FABP Monoclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 8 to 9 Days
$299.45
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of FABP5 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of FABP5 expression in mouse skin (A), mouse thymus (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry: FABP5/E-FABP Antibody [NBP2-38659] - Staining of human esophagus shows strong cytoplasmic and nuclear positivity in squamous epithelial cells. Western Blot: FABP5/E-FABP Antibody [NBP2-38659] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: RT-4 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$245.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded stomach tissue 100 μg Log in to see 15 to 18 Days
$332.00
Details
Human Sheep Un-conjugated ELISA, IHC, IHC (p), WB Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μg Log in to see 11 to 14 Days
$639.83
Details

Top referenced anti-FABP5 Antibodies

  1. Human Monoclonal FABP5 Primary Antibody for CyTOF, FACS - ABIN4899421 : Liebertz, Lechner, Masood, Sinha, Han, Puri, Correa, Epstein: Establishment and characterization of a novel head and neck squamous cell carcinoma cell line USC-HN1. in Head & neck oncology 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal FABP5 Primary Antibody for WB - ABIN515491 : Kovacevic, Chikhani, Lui, Sivagurunathan, Richardson: The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways. in Antioxidants & redox signaling 2013 (PubMed)

  3. Human Polyclonal FABP5 Primary Antibody for IF, WB - ABIN6680032 : Pan, Xiao, Liao, Chen, Peng, Zhang, Mu, Wu: Fatty acid binding protein 5 promotes tumor angiogenesis and activates the IL6/STAT3/VEGFA pathway in hepatocellular carcinoma. in Biomedicine & pharmacotherapy 2018 (PubMed)

More Antibodies against FABP5 Interaction Partners

Human Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) interaction partners

  1. FABP5 might promote the carcinogenesis and metastasis of cervical cancer via up-regulating MMP-2 and MMP-9.

  2. The E-FABP concentration in tears appears to be related to ocular surface epithelial damage and tear stability in patients with dry eye disease in Sjogren syndrome.

  3. FABP5 promotes tumor angiogenesis via activation of the IL6/STAT3/VEGFA signaling pathway in hepatocellular carcinoma.

  4. FABP5 promotes lipolysis of lipid droplets, de novo fatty acid synthesis and activation of NF-kappaB signaling in cancer cells.

  5. Although FABP5 facilitates brain endothelial cell uptake of fatty acids, it has limited effects on brain endothelial cell uptake.

  6. Results show that circulating FABP5 is associated with decreased cholesterol efflux capacity (CEC) and carotid atherosclerosis, suggesting that FABP5 level is a regulatory factor of CEC and a potential biomarker for residual risk of atherosclerosis.

  7. Compared to control group, breast cancer patients show higher FABP4 and FABP5 blood levels. Our data suggest that, particularly, circulating FABP4 levels could be considered a new independent breast cancer biomarker. Our work translates basic science data to clinic linking the relationship between adipose tissue and lipid metabolism to breast cancer.

  8. the critical role of FABP5 in activating the TGF-beta signaling pathway during radiation-induced human skin fibrosis

  9. Study identified FABP5 to be involved in the progressive intestinal injury associated with the development of Crohn's Disease complications via their effects on intestinal innate immunity.

  10. Findings show that FABP5 expression is up-regulated in hepatocellular carcinoma (HCC), and provide evidence that that it could play a crucial role of tumor progression, invasion and metastasis in HCC through EMT induction.

  11. Circulating levels of AFABP and EFABP are not decreased in Lipodystrophy despite adipose tissue loss in contrast to other adipokines including leptin and adiponectin.

  12. A high expression ratio between FABP5 and CRABPII may be related to CP tumor recurrence and ATRA could be a potential therapeutic agent for CP chemotherapy.

  13. Data suggest that antinociceptive agent SBFI-26 binds at a portal site as well as at the canonical site in the substrate pocket of FABP5 and FABP7; only the S form of SBFI-26 binds to both FABP5 and FABP7 in their co-crystal structures; SBFI-26 induces conformational changes in FABP5 and FABP7.

  14. secreted FABP4 and FABP5 from adipocytes as adipokines differentially affect transcriptional and metabolic regulation in ADSC near adipocytes

  15. FABP5 plays an important role in the carcinogenesis and metastasis of cervical cancer, and FABP5 may be a novel predictor for prognostic assessment of cervical cancer patients.

  16. FABP5 promoted VEGF expression and angiogenesis through PPARgamma which was activated by fatty acids transported by FABP5.

  17. FABP5 is associated with increased subclinical atherosclerosis

  18. the balance between FABP4 and FABP5 in endothelial cells may be important in regulation of angiogenic versus quiescent phenotypes in blood vessels.

  19. Long chain fatty acids suppress the oncogenic properties of FABP5-expressing carcinoma cells in cultured cells.

  20. silencing of Sp1, c-Myc or FABP5 expression led to a significant decrease in cell proliferation, indicating that up-regulation of FABP5 expression by Sp1 and c-Myc is critical for the proliferation of prostate cancer cells

Mouse (Murine) Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) interaction partners

  1. This study demonstrated the role of FABPs may play an important role in drug-seeking behavior under stressful conditions.

  2. Fabp4/5 confers protection against metabolic diseases but does not extend lifespan.

  3. Lack of PPARbeta/delta-expression, TUNEL reaction, RA receptor (RAR)beta, and cellular retinoic acid-binding protein (CRABP)-II were induced in E-FABP-positive septoclasts under RA excess, suggesting the growth arrest/cell-death of septoclasts, whereas cartilage-derived retinoic acid-sensitive protein (CD-RAP) inducing the cell growth arrest or morphological changes was induced in septoclasts under VA deficiency.

  4. A 42.1 +/- 12.6% decrease in the BBB transport of (14) C-DHA in 8-month-old AD transgenic mice relative to wild-type mice was associated with a 34.5 +/- 6.7% reduction in FABP5 expression in isolated brain capillaries. Short-term spatial and recognition memory deficits were seen in AD mice on a 6-month n-3 fatty acid-depleted diet, but not those on control diet.

  5. Using a yeast two-hybrid screen, immunoprecipitation, microscale thermophoresis analysis and cellular fractionation, we discovered that Fabp5 interacts with the calnexin cytoplasmic C-tail domain at the endoplasmic reticulum. These observations identify Fabp5 as a previously unrecognized calnexin binding partner.

  6. Following infection with Listeria monocytogenes, we observed similar clonal expansion, contraction and formation of memory CD8 T cells in WT and E-FABP-/- mice. Analysis of Listeria-specific CD4 T cells revealed no defect in the expansion, contraction, and formation of memory CD4 T cells in E-FABP-/- mice. Our data demonstrate that E-FABP is dispensable for antigen-specific T cell response following bacterial infection.

  7. Genetic deletion of fatty acid-binding protein 5 (FABP5) in mice reduces uptake of exogenous docosahexaenoic acid (DHA) into brain endothelial cells and brain capillaries and reduces brain parenchymal levels of endogenous DHA. Therefore, FABP5 in the brain endothelial cell is a crucial contributor to the brain levels of DHA. Critically, lowered brain DHA levels in FABP5(-/-) mice occurred in tandem with cognitive deficits

  8. the balance between FABP4 and FABP5 in endothelial cells may be important in regulation of angiogenic versus quiescent phenotypes in blood vessels.

  9. Mice lacking FABP5 and FABP7, which exhibit highest affinities for endocannabinoids, possessed elevated levels of the endocannabinoid anandamide and the related N-acylethanolamines palmitoylethanolamide and oleoylethanolamide.

  10. These studies show, for the first time, a correlation between FABP5 and EGFR in enhancing TNBC metastasis through a novel mechanism

  11. loss of FABP5 promotes a more anti-inflammatory response.

  12. Circulating levels of GIP were significantly decreased in FABP5-deficient mice.

  13. The frameshift and missense mutations in FABP3, FABP5, and FABP7 genes have been identified in schizophrenia and autism spectrum disorder in humans and in mouse behavioral studies.

  14. FABP5 contributes to the development of Diet-induced obesity in a gastric inhibitory polypeptide-dependent manner.

  15. Data indicate that epidermal fatty acid binding protein (E-FABP)-immunoreactivity was found in the entire cytoplasm and on the mitochondrial outer membrane.

  16. FABP4/5 play an indispensable role in thermogenesis in brown adipose tissue and skeletal muscle.

  17. FABP7 and FABP5 are differentially expressed in oligodendrocyte lineage cells and regulate their proliferation and/or differentiation.

  18. Data indicate that the fatty acid-binding protein 5 (FABP5)/nuclear receptor peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) pathway induces the expression of cognition-associated genes.

  19. Capillary endothelial FABP4/5 are required for (fatty acid)FA transport into FA-consuming tissues that include the heart.

  20. Our findings establish that FABP5 is critical for mammary tumor development

Pig (Porcine) Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) interaction partners

  1. FABP4 gene expression level in adipose tissue was higher than in muscle. In contrast, FABP5 was expressed at low levels in adipocytes and muscle tissues. Low and moderate correlations between FABP4 and FABP5 gene expression were observed in muscle and in backfat, respectively.

  2. QTL and haplotype analysis revealed that both FABP4 and FABP5 (clustered in mammals) are major candidate genes for the FAT1 QTL; the most likely position for the FAT1 QTL is between these two genes.

FABP5 Antigen Profile

Protein Summary

This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.

Gene names and symbols associated with FABP5

  • fatty acid binding protein 5 (FABP5) antibody
  • fatty acid binding protein 5, epidermal (Fabp5) antibody
  • fatty acid binding protein 5 (Fabp5) antibody
  • fatty acid binding protein 5 (psoriasis-associated) (Fabp5) antibody
  • cationic amino acid transporter 3 pseudogene (LOC609554) antibody
  • C-FABP antibody
  • DA11 antibody
  • E-FABP antibody
  • EFABP antibody
  • FABP5 antibody
  • Fabpe antibody
  • KFABP antibody
  • Klbp antibody
  • mal1 antibody
  • PA-FABP antibody
  • PAFABP antibody

Protein level used designations for FABP5

epidermal-type fatty acid-binding protein , fatty acid-binding protein, epidermal , psoriasis-associated fatty acid-binding protein homolog , fatty acid binding protein 5 , epithelial fatty acid-binding protein , keratinocyte lipid-binding protein , cutaneous fatty acid-binding protein , fatty acid-binding protein 5 , epidermal fatty acid-binding protein , E-FABP , differentiation-associated lipid-binding protein LP2

GENE ID SPECIES
2171 Homo sapiens
420197 Gallus gallus
100270712 Ovis aries
16592 Mus musculus
140868 Rattus norvegicus
574074 Sus scrofa
100337640 Cavia porcellus
281760 Bos taurus
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