Fc Fragment of IgA, Receptor For (FCAR) ELISA Kits

FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. Additionally we are shipping Fc Fragment of IgA, Receptor For Antibodies (160) and Fc Fragment of IgA, Receptor For Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FCAR 2204 P24071
FCAR    
FCAR    
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Top Fc Fragment of IgA, Receptor For ELISA Kits at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.37 ng/mL 0.78 ng/mL - 50 ng/mL 96 Tests 13 to 16 Days
$700.00
Details
Mouse 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Rat 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Rabbit 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Pig 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Chicken 0.469 ng/mL 0.781-50 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Monkey 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Human
  96 Tests 26 to 36 Days
$899.80
Details

Top referenced Fc Fragment of IgA, Receptor For ELISA Kits

  1. Human FCAR ELISA Kit for Sandwich ELISA - ABIN417632 : Moresco, Speeckaert, Zmonarski, Krajewska, Komuda-Leszek, Perkowska-Ptasinska, Gesualdo, Rocchetti, Delanghe, Vanholder, Van Biesen, Delanghe: Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis. in BBA clinical 2016 (PubMed)

More ELISA Kits for Fc Fragment of IgA, Receptor For Interaction Partners

Cow (Bovine) Fc Fragment of IgA, Receptor For (FCAR) interaction partners

  1. have mapped the IgA binding site of bovine IgA Fc receptor and show that, in common with CD89, Tyr-35 in the B-C loop is essential for IgA binding

Pig (Porcine) Fc Fragment of IgA, Receptor For (FCAR) interaction partners

  1. FcalphaRI contain a 792-base-pair open reading frame, encoding a 264-amino-acid transmembrane glycoprotein with a predicted molecular mass of 29.4 kDa.

Human Fc Fragment of IgA, Receptor For (FCAR) interaction partners

  1. FcalphaRI-induced cytokine production is orchestrated via upregulation of cytokine translation and caspase-1 activation, which is dependent on glycolytic reprogramming.

  2. In transgenic mice, IgAN pathogenesis involves impaired clearance of abnormal IgA via CD89, primarily by the Kupffer cells. Conditional IgAN progression in CD89 transgenic mice thus reveals important aspects of IgAN pathogenesis.

  3. a novel Fcar splice variant termed variant APD isolated from a healthy volunteer that lacks only the IgA-binding EC1 domain, is reported.

  4. Findings suggest a basis for the use of Fc receptor I for IgA (FcalphaRI) as a molecular target for the treatment of lupus.

  5. induces different forms of neutrophil death, depending on the inflammatory microenvironment

  6. this study examined the expression of IL-4 mRNA, IFN-c mRNA and FcaRI mRNA in tonsillar mononuclear cells of IgA nephropathy9(IgAN) patients and non-IgAN patients.

  7. FCAR polymorphism is not associated with high susceptibility to IGA nephropathy in caucasians.

  8. Abnormally glycosylated IgA1 and soluble CD89-IgA and IgA-IgG complexes, features of primary IgA nephropathy, are also present in alcoholic cirrhosis.

  9. Genetic variation at the promoter region of IgA receptor is associated with IgA nephropathy.

  10. These results suggest a role of anti-FcaRI Fab as a negative regulator in controlling the magnitude of the innate immune response

  11. Glycosylation of the CH2/CH3 interface inhibits interaction with the pathogen IgA binding protein SSL7, while maintaining binding of pIgR, essential to the biosynthesis and transport of SIgA.

  12. In this study, human mammary carcinoma cells are efficiently killed when incubated with human neutrophils and tumor-specific FcalphaRI bispecific or immunoglobulin A antibodies.

  13. Data show that the Fc(alpha)RI 844 A>G polymorphism is not associated with systemic sclerosis or rheumatoid arthritis sceptibility.

  14. FcalphaRI defines a function for pentraxins in inflammatory responses involving neutrophils and macrophages. It also highlights the innate aspect of otherwise humoral immunity-associated antibody receptors.

  15. There is an association between the levels of sCD89-IgA complexes in serum and the severity of IgA nephropathy, and a possible genetic component in regulating the production or expression of sCD89.

  16. Endocytosis of FcalphaR is clathrin- and dynamin-dependent, but is not regulated by Rab5, and the endocytic motif is not located in the cytoplasmic domain of FcalphaR.

  17. CD89 circulates in a high molecular mass form in complex covalently linked to IgA and contributes to the formation of polymeric serum IgA.

  18. study suggests that expression of the FcR splice isoform DeltaEC2 but not Delta66EC2 is differentially regulated in a cell type-specific manner and in response to inflammatory and/or infectious processes

  19. The Fc alpha receptor 5'-flanking region from -102 to -64 relative to the ATG translation initiation codon is essential for promoter activity and contains two functional binding motifs for C/EBP and Ets family members at -74 and -92, respectively.

  20. there is a bivalent, pH-dependent interaction between FcalphaRI and IgA with important implications for cytokine-dependent phagocytosis of IgA and the FcalphaRI-mediated degradation or recycling of IgA

Fc Fragment of IgA, Receptor For (FCAR) Antigen Profile

Antigen Summary

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with FCAR

  • Fc fragment of IgA receptor (FCAR) antibody
  • Fc fragment of IgA, receptor for (FCAR) antibody
  • CD89 antibody

Protein level used designations for FCAR

IgA Fc receptor , immunoglobulin A Fc receptor , immunoglobulin alpha Fc receptor , Fc fragment of IgA, receptor for, isoform 7 , Fc alpha receptor

GENE ID SPECIES
503555 Bos taurus
664734 Macaca mulatta
100050205 Equus caballus
100137567 Papio anubis
100144539 Sus scrofa
2204 Homo sapiens
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