Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) ELISA Kits

Human Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) interaction partners

1. Collectively, these results indicate that the amino acid substitution Ala78Asp resulting in the HNA-1c allotype leads to higher affinity toward human IgG, enhancement of neutrophil activation, and possibly effective clearance of malaria by intracellular reactive oxygen species.

2. SHP-2 is activated by CD16b crosslinking in neutrophils.

3. FCGR3B deficiency due to copy number variations may predispose to eosinophilic granulomatosis with polyangiitis.

4. low copy numbers of FCGR2A and FCGR3B to be common risk factors for systemic lupus nephritis (SLE) and ANCA-associated systemic vasculitis (AASV).

5. The FCGR3B NA1/NA1 genotype is associated with hypersensitivity reactions to adalimumab in Japanese patients with Rheumatoid Arthritis.

6. Data suggest association of FCGR3B deletion with increased risk of rheumatoid arthritis (RA) in a large cohort.

7. Gene copy number variation (CNV) of the PKLR, FCGR2A, FCGR2C, and FCGR3 genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria.

8. Association between Fc gamma Receptor IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.

9. We conclude that FCGR3A CNVs are a major risk factor for female sarcoidosis and FCGR3B CNVs may also affect the development of sarcoidosis.

10. CD16 and CD35 are important for neutrophil internalization of M. tuberculosis, whereas HIV-1 infection adversely affects opsonophagocytosis.

11. There was no aberration in FCGR3B allele/genotype frequencies in sarcoidosis patients compared to controls.

12. Results showed that susceptibility to systemic lupus erythematosus was associated with the FCGR3B*01 allele, as well as with the FCGR3B*01/*01 and FCGR3B*01/*02 genotypes.

13. FcgammaRIIIB allelic distribution was similar among pediatric Guillain-Barre syndrome patients and controls.

14. Lower copy numbers (

15. This metaanalysis indicates that polymorphisms in the pathways of immune complex clearance, such as the FcgammaRIIIa, FcgammaRIIIb, and ITGAM genotypes, are potential susceptibility genes for neuropsychiatric systemic lupus erythematosus.

16. data show that cross-linking FcgammaRIIIb is responsible for NET formation by the human neutrophil

17. our method allows determining the CNV status of the FCGR locus, we identified association of CNV in FCGR3B to RA and showed a functional relationship between CNV in the FCGR3A gene and CD16A expression.

18. Fc-gamma receptor polymorphisms differentially influence susceptibility to systemic lupus erythematosus and lupus nephritis.

19. the results of this meta-analysis indicated that low FCGR3B CN increased susceptibility to autoimmune diseases--{REVIEW}

20. Data show that gains or losses in copy numbers of Fc gamma receptors FCGR3A were less frequent than for FCGR3B and FCGR2C.