anti-Fibroblast Growth Factor Receptor Antibodies

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.

Type
  • 2
    Primary antibodies
Antigen
  • 2
Reactivity
  • 2
Application
  • 2
Host
  • 1
  • 1
Clonality
  • 1
  • 1
Clone
  • 1
Isotype
  • 1
  • 1
Format
  • 2
2 Products
ReactivityHuman
Application WB
Order details Cat. No. ABIN2267319
$652.14
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2267321
$939.71
1 mg
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
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Fibroblast Growth Factor Receptor (FGFR) Antigen Profile

Protein Summary

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol- 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by ubiquitination, internalization and degradation (By similarity).

Gene names and symbols associated with FGFR

  • heartless (htl) antibody
  • fibroblast growth factor receptor 1 L homeolog (fgfr1.L) antibody
  • fibroblast growth factor receptor (FGFR) antibody
  • fibroblast growth factor receptor 1 S homeolog (fgfr1.S) antibody
  • fibroblast growth factor receptor (fgfr) antibody
  • fibroblast growth factor receptor 1 (FGFR1) antibody
  • fibroblast growth factor receptor 1 (fgfr1) antibody
  • fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L) antibody
  • basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849) antibody
  • ach antibody
  • bfgfr antibody
  • cd331 antibody
  • cd333 antibody
  • cek antibody
  • cek2 antibody
  • CG7223 antibody
  • CT22273 antibody
  • CT39172 antibody
  • DFGF-R1 antibody
  • DFGF-R2 antibody
  • Dfr-1 antibody
  • Dfr1 antibody
  • DFR1/DFGF-R2 antibody
  • Dmel\\CG7223 antibody
  • DmHD-38 antibody
  • DPR3 antibody
  • dtk1 antibody
  • DTRK(FR1) antibody
  • EMS2 antibody
  • FGF-R2 antibody
  • fgfbr antibody
  • fgfr antibody
  • fgfr-1 antibody
  • fgfr-3 antibody
  • fgfr1 antibody
  • FGFR2 antibody
  • flg antibody
  • FLG-1 antibody
  • flt-2 antibody
  • flt2 antibody
  • Fr1 antibody
  • hbgfr antibody
  • HD-38 antibody
  • hsfgfr3ex antibody
  • Htl antibody
  • HTL/FGFR1 antibody
  • i79 antibody
  • i100 antibody
  • i150 antibody
  • j372 antibody
  • jtk4 antibody
  • kal2 antibody
  • n-sam antibody
  • ogd antibody
  • Tk1 antibody
  • X1FGFR antibody
  • XFGFR-1 antibody
  • xfgfr1 antibody
  • XFGFRA2 antibody

Protein level used designations for FGFR

CG7223-PA , CG7223-PB , CG7223-PC , FGF receptor , fibroblast growth factor receptor , fibroblast growth factor receptor 1 , htl-PA , htl-PB , htl-PC , FGFR-1 , fibroblast growth factor receptor-1 , fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) , ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) , basic fibroblast growth factor receptor 1 , basic fibroblast growth factor receptor 1-like

GENE ID SPECIES
42160 Drosophila melanogaster
399444 Xenopus laevis
373310 Strongylocentrotus purpuratus
394418 Xenopus laevis
445706 Ciona intestinalis
475582 Canis lupus familiaris
548648 Xenopus (Silurana) tropicalis
779370 Xenopus laevis
6037802 Culex quinquefasciatus
100390192 Callithrix jacchus
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