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FSTL1 encodes a protein with similarity to follistatin, an activin-binding protein. Additionally we are shipping FSTL1 Antibodies (121) and FSTL1 Proteins (31) and many more products for this protein.
Showing 10 out of 65 products:
Human FSTL1 ELISA Kit for Sandwich ELISA - ABIN423684
Kim, An, Nam, Jeon, Suh: Serum S100A8/A9, but not follistatin-like protein 1 and interleukin 18, may be a useful biomarker of disease activity in adult-onset Still's disease. in The Journal of rheumatology 2012
Show all 5 Pubmed References
Human FSTL1 ELISA Kit for Sandwich ELISA - ABIN1672869
Sundaram, Common, Gopal, Srikanta, Lakshman, Lunny, Lim, Tanavde, Lane, Sampath: 'See-saw' expression of microRNA-198 and FSTL1 from a single transcript in wound healing. in Nature 2013
Show all 3 Pubmed References
Mouse (Murine) FSTL1 ELISA Kit for Sandwich ELISA - ABIN430956
Galimov, Hartung, Trepp, Mader, Flück, Linke, Blüher, Christ, Krützfeldt: Growth hormone replacement therapy regulates microRNA-29a and targets involved in insulin resistance. in Journal of molecular medicine (Berlin, Germany) 2015
Study suggests that follistatin like 1 plays an important role in lung fibrosis, and may serve as a novel therapeutic target for treatment of silicosis.
Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma.
Study found that FSTL1 was downregulated in non-small cell lung cancer (NSCLC) cells. FSTL1 overexpression suppressed tumor cell proliferation, altered cell cycle and induced apoptosis in addition to inhibiting cell survival, migration and invasion. Altogether, results revealed the critical tumor-suppression function of FSTL1 in NSCLC progression, suggesting it as an important factor in NSCLC progression.
Smad3 (show SMAD3 ELISA Kits) knockdown could restore the inhibition of cell proliferation induced by FSTL1 overexpression in MDAMB231FSTL1 cells, indicating that the antiproliferative effect of FSTL1 overexpression may be associated with Smad3 (show SMAD3 ELISA Kits) involved TGFbeta (show TGFB1 ELISA Kits) signaling pathway regulation. This study identified FSTL1 as an inhibitor of cell proliferation in MDAMB231 and 231BR cell lines
Dendritic cell-mediated immunity was activated by FSTL1.
Fstl1serves an important role in liver fibrosis and target deletion of Fstl1 attenuated HSCs activation through suppressing TGFbeta1 (show TGFB1 ELISA Kits)/Smad3 (show SMAD3 ELISA Kits) signaling pathway.
Results showed that: 1- FSTL-1 expression is localized to the stromal compartment of the pancreas; 2- FSTL-1 expression is reduced in pancreatic cancer, and 3- FSTL-1 inhibited pancreatic cancer cell proliferation.
Data show that follistatin-like 1 (FSTL1) contributed to unfavorable post-surgical outcome of hepatocellular carcinoma (HCC) patients via inhibiting cell apoptosis.
results indicate that rs1259293 is associated with an increased risk and unfavorable postoperative prognosis of renal cell carcinoma, possibly by down-regulating FSTL1 expression in renal tissues.
Data provide evidence that FSTL1 modestly affects the proliferation of breast cancer cells and vascular endothelial cells. These findings improve the understanding of the functions of FSTL1 in breast cancer development and angiogenesis.
this study shows that FSTL-1 modulates IL-17 (show IL17A ELISA Kits) signaling via IL-17RC (show IL17RC ELISA Kits) regulation in stromal cells
FSTL1 may exert its actions through the modulation of Akt (show AKT1 ELISA Kits) signaling.
FSTL1 is a secreted osteoclastogenic factor that plays a critical role in osteoclast formation via the NF-kappaB (show NFKB1 ELISA Kits) and MAPKs signaling pathways.
study indicates a pivotal role for Fstl1 in early stage of lung airway smooth muscle development
This study reveals that Fstl1 is essential for the acute repair of the infarcted myocardium and that stimulation of early fibroblast activation is a novel function of Fstl1.
Deletion of Fstl1 from the endocardial/endothelial lineage results in deformed mitral valves, which cause regurgitation, heart failure, and early cardiac death.
A critical role for the Smad3 (show SMAD3 ELISA Kits)-c-Jun (show JUN ELISA Kits) pathway in the regulation of Fstl1.
FSTL1 may induce epithelial mesenchymal transition and airway remodeling by activating autophagy.
tightly spatial interaction of FSTL1 and BMP4 (show BMP4 ELISA Kits) signaling plays an essential role in lung development
a new role for FSTL1 in the development of radial glial scaffolds and the neuronal migration of upper-layer projection neurons, is reported.
This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis.
follistatin-like protein 1
, follistatin-related protein 1
, TGF-beta-inducible protein TSC-36
, follistatin-like 1
, Follistatin-related protein 1
, follistatin like 1 L homeolog