Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) ELISA Kits

FOXC2 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. Additionally we are shipping FOXC2 Antibodies (112) and FOXC2 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FOXC2 14234 Q61850
FOXC2 171356  
FOXC2 2303 Q99958
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Top FOXC2 ELISA Kits at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.056 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
$713.90
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Rat
  96 Tests Log in to see 2 to 3 Days
$867.90
Details
Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Cow 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Rabbit
  96 Tests Log in to see 15 to 18 Days
$707.14
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Guinea Pig
  96 Tests Log in to see 15 to 18 Days
$707.14
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Mouse
  96 Tests Log in to see 15 to 18 Days
$707.14
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Chicken
  96 Tests Log in to see 15 to 18 Days
$707.14
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Monkey
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$707.14
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Sheep
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$707.14
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More ELISA Kits for FOXC2 Interaction Partners

Mouse (Murine) Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) interaction partners

  1. Foxc2 influences alveolar epithelial cell differentiation during lung development

  2. Study shows that alpha melanocyte stimulating hormone and forkhead box C2 protein promote fatty acid oxidation through C/EBPbeta negative transcription in mice adipose tissue.

  3. FOXC1 and FOXC2 are essential regulators of lymphangiogenesis and may have roles in lymphatic-associated diseases

  4. Compound, NC-specific Foxc1; Foxc2 homozygous mutant mice have more severe defects in structures of the ocular surface, such as the cornea and eyelids, accompanied by significant declines in the expression of another key developmental factor, Pitx2, and its downstream effector Dkk2, which antagonizes canonical Wnt signaling.

  5. Foxc1 and Foxc2 maintain glomerular podocyte integrity by regulating the gene expression. Foxc2 plays a more critical role than Foxc1.

  6. Foxc1 and Foxc2 have a role in kidney and axial skeleton development.

  7. Our results are consistent with previous reports of Foxc2 expression during early embryogenesis and the Foxc2(CreERT2) mouse provides a tool to investigate spatiotemporal roles of Foxc2 and contributions of Foxc2(+) expressing cells during mouse embryogenesis.

  8. Conditional knockout of Foxc2 gene in kidney has been generated using conditional alleles of single-exon gene by double-selection system.

  9. Data show that segregation of Foxc2 and NFATc1 transcription factor is closely associated with the highly polarized expression of connexins Cx37, Cx43, and Cx47.

  10. deletion of Foxc1 and Foxc2 specifically in Pax3-positive cells affects cell fate choices in the dermomyotome of somites at forelimb level, promoting the myogenic cell fate at the expense of endothelial cells that migrate to the limb

  11. Foxc2 in pharyngeal arch mesenchyme is important for aortic arch artery remodelling and ventricular septum formation

  12. Foxc2 enhances proliferation of preadipocytes and inhibits apoptosis of preadipocytes by activating the Akt/mTORC1 and ERK/mTORC1 signaling pathways

  13. In murine models, inducible deletion of Foxc2 within the lymphatic vasculature led to cell-cell junction defects, regression of valves, and focal vascular lumen collapse, which triggered generalized lymphatic vascular dysfunction and lethality.

  14. Foxc2 and Cx37 are elements in a common molecular pathway directing lymphangiogenesis.

  15. Foxc2 induces Wnt4 and Bmp4 expression during muscle regeneration and osteogenesis.

  16. studies suggest an important role for Egr-1, which, by repressing FOXC2 expression, promotes energy storage in WAT and favored the development of obesity under high energy intake

  17. Results indicate that Foxc2 plays an important role in osteoblastogenesis by promoting osteoblast proliferation, survival and differentiation through up-regulation of integrin beta1 in response to stimuli which induce bone formation.

  18. Dysmorphogenesis of lymph nodes in Foxc2 haploinsufficient mice

  19. these findings demonstrate that haplodeficiency of Foxc2 results in impaired formation of tumor blood vessels as well as reduced tumor growth and thereby provide evidence that Foxc2 is critical for tumor development and angiogenesis.

  20. Foxc2 may have regulatory functions independent of its nuclear transcriptional activity.

Human Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) interaction partners

  1. that FOXC2 could promote the invasion ability of normal trophoblast cells by epithelial-mesenchymal transition -mediated Hedgehog pathway

  2. REVIEW: current understanding of FOXC2 and provide potential mechanistic explanations of the relationship between FOXC2 and cancer, as well as discuss the prospect for future research in the promising prognostic value of FOXC2 in cancer

  3. The finding of rare LAMA5 variants together with FOXC2 mutations in lymphedema-distichiasis syndrome suggests that these mutations may be co-responsible for these disorders and most likely interfere with the function of lymphatics.

  4. In FOXC2 knockdown cell lines, CXCR4, a downstream target of FOXC2, can restore osteosarcoma cell invasiveness and metastasis to the lung

  5. Knockdown of FOXC2 inhibited HCC cell growth, migration, and invasion in vitro, as well as tumor growth.

  6. Studied interactions between protein kinase C alpha (PKCalpha), FOXC2, and p120-catenin (CTNND1) in breast cancer, cell migration/ invasion; found PKCalpha acts as an upstream regulator of FOXC2, which in turn represses the expression of p120-catenin, in both in endocrine resistant ER+breast cancer and basal A triple negative breast cancer.

  7. FOXC2 and CLIP4 activity correlates to the presence of

  8. either a complete loss or a significant gain of FOXC2 function can cause a perturbation of lymphatic vessel formation leading to lymphedema.

  9. Association of polymorphisms near the FOXC2 gene with the risk of varicose veins in ethnic Russians.

  10. respectively. Foxc2 is expressed in the developing kidney and therefore congenital renal anomalies may well be associated, potentially as a low penetrance feature. We propose that all individuals diagnosed with Lymphedema distichiasis syndrome should have a baseline renal ultrasound scan at diagnosis

  11. Genomic analysis of blood and excised valve tissue showed down-regulation of FOXC1 but also FOXC2 expression in the diseased aortic valve. This allows us to speculate on the potential role of FOXC1 in aortic valve anomalies.

  12. This is the first report of a FOXC2 mutation in hereditary distichiasis in the Chinese population. The findings expand the FOXC2 mutation spectrum and contribute to the understanding of the genotype-phenotype correlation of this disease.

  13. FOXC2 promoted the glycolysis in progression of nasopharyngeal carcinoma by activating YAP signaling

  14. FOXC1 and FOXC2 are essential regulators of lymphangiogenesis and may have roles in lymphatic-associated diseases

  15. Authors concluded that the lncRNA FOXC2-AS1 may promote doxorubicin resistance in OS by increasing the expression of transcription factor FOXC2, further facilitating ABCB1 expression.

  16. we demonstrate that FOXC2 is an important determinant of PCa stem-cell attributes, dictating the biochemical shift to ADT- and chemo-resistance

  17. our data demonstrate that FOXC2 regulates EMT, stem cell traits, ZEB1 expression and metastasis in a p38-dependent manner, and attest to the potential utility of p38 inhibitors as antimetastatic agents.

  18. Moreover, PLK1 activity is important for FOXC2 protein stability, since PLK1 inhibition reduces FOXC2 protein levels.

  19. Data suggest that forkhead box protein C2 (FOXC2) could be a potential therapeutic target for overcoming cisplatin (CDDP) resistance in ovarian cancer.

  20. High expression of FOXC2 is associated with pancreatic ductal adenocarcinoma.

FOXC2 Antigen Profile

Antigen Summary

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in the development of mesenchymal tissues.

Gene names and symbols associated with FOXC2

  • forkhead box C2 (FOXC2) antibody
  • forkhead box C2 (Foxc2) antibody
  • forkhead box C2 (MFH-1, mesenchyme forkhead 1) (FOXC2) antibody
  • Fkh14 antibody
  • FKHL14 antibody
  • FOXC2 antibody
  • Hfhbf3 antibody
  • LD antibody
  • MFH-1 antibody
  • MFH1 antibody

Protein level used designations for FOXC2

forkhead box C2 (MFH-1, mesenchyme forkhead 1) , forkhead box C2 , forkhead box protein C2 , forkhead box protein C2-like , BF-3 , brain factor 3 , forkhead homolog 14 , forkhead-related protein FKHL14 , mesenchyme fork head protein 1 , transcription factor FKH-14 , HFH-BF-3 , forkhead box C2 (MFH-1 mesenchyme forkhead 1) , winged helix transcriptional factor MFH-1 , MFH-1,mesenchyme forkhead 1 , forkhead, Drosophila, homolog-like 14

GENE ID SPECIES
468058 Pan troglodytes
694852 Macaca mulatta
100036555 Equus caballus
100407050 Callithrix jacchus
14234 Mus musculus
171356 Rattus norvegicus
396039 Gallus gallus
2303 Homo sapiens
489671 Canis lupus familiaris
507300 Bos taurus
101103500 Ovis aries
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