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anti-Formin Binding Protein 1 (FNBP1) Antibodies

The protein encoded by FNBP1 is a member of the formin-binding-protein family. Additionally we are shipping Formin Binding Protein 1 Kits (10) and Formin Binding Protein 1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FNBP1 23048 Q96RU3
FNBP1 14269 Q80TY0
FNBP1 192348 Q8R511
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Top anti-Formin Binding Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, IHC, WB ABIN185286 staining (0.25µg/ml) of human testis lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Fnbp1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Pancreas 100 μL 2 to 3 Days
$289.00
Details
Bat Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Anti-FNBP1 / FBP17 antibody IHC staining of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN1101602 dilution 10 ug/ml. Anti-FNBP1 / FBP17 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Horse Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Goat Un-conjugated WB   0.1 mg 4 to 8 Days
$462.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded testis tissue 100 μg 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of various cells, using FNBP1 antibody. Western blot analysis of extracts of various cell lines, using FNBP1 antibody (ABIN4903690) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 20s. 100 μL 11 to 13 Days
$366.77
Details
Horse Rabbit Un-conjugated IHC, IHC (p) 100 μg 11 to 14 Days
$507.83
Details
Human Goat Un-conjugated EIA, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 6 to 8 Days
$495.00
Details

Top referenced anti-Formin Binding Protein 1 Antibodies

  1. Human Polyclonal FNBP1 Primary Antibody for ELISA, WB - ABIN250282 : Hu, Mukhopadhyay, Craig: Transducer of Cdc42-dependent actin assembly promotes epidermal growth factor-induced cell motility and invasiveness. in The Journal of biological chemistry 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal FNBP1 Primary Antibody for ELISA, WB - ABIN547343 : Kamioka, Fukuhara, Sawa, Nagashima, Masuda, Matsuda, Mochizuki: A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis. in The Journal of biological chemistry 2004 (PubMed)

  3. Human Polyclonal FNBP1 Primary Antibody for IP, WB - ABIN4312240 : Suman, Mishra, Chander: High expression of FBP17 in invasive breast cancer cells promotes invadopodia formation. in Medical oncology (Northwood, London, England) 2018 (PubMed)

More Antibodies against Formin Binding Protein 1 Interaction Partners

Human Formin Binding Protein 1 (FNBP1) interaction partners

  1. FBP17 and CIP4 prime the membrane of resting cells for fast endophilin-mediated endocytosis by recruiting the 5'-lipid phosphatase SHIP2 and lamellipodin to mediate the local production of phosphatidylinositol-3,4-bisphosphate and endophilin pre-enrichment.

  2. Results suggest that FBP17 is highly expressed in breast cancer cells and facilitates the invasion of breast cancer cells.

  3. FBP17 is the local activator of actin polymerization that is inhibited by PM tension in the feedback loop that regulates cell migration.

  4. Knockdown of PSTPIP2 inmacrophages enhances the assembly of FBP17, leading to'hyperactivation' of actin nucleation at podosomes and ECM degradation.

  5. F-BAR protein Rapostlin, whose activity is regulated by Rnd2, plays a key role in spine formation through the regulation of membrane dynamics.

  6. Results suggest a functional link between FBP17-dependent membrane tubulation and clathrin-dependent budding. Clathrin spatially directs membrane invaginations that lead to the generation of endocytic vesicles larger than those enclosed by the coat.

  7. co-immunoprecipitation of endogenous proteins in 293T cells confirms physiological relevance of TNKS as interaction partner of FBP17

  8. FBP17 interacts with dynamin and regulates endocytosis by forming vesicotubular structures

  9. Data indicate that PCH protein family members such as FBP17 couple membrane deformation to actin cytoskeleton reorganization in various cellular processes.

  10. FBP17 is recruited to clathrin-coated pits in the late stage of endocytosis, indicating its physiological role.

  11. N-WASP-WIP complex-mediated actin polymerization is activated by phosphatidylserine-containing membranes depending on membrane curvature in the presence of Toca-1 or FBP17 and in the absence of Cdc42 and phosphatidylinositol (4,5)-bisphosphate.

  12. formin-binding protein 17 (FBP17) recruits WASP, WASP-interacting protein (WIP), and dynamin-2 to the plasma membrane and that this recruitment is necessary for the formation of podosomes and phagocytic cups.

  13. Rat rapostlin protein has 93% aa identity to human FBP17.

  14. FNBP1 family proteins (FNBP1 and TRIP10) consist of FCH, FBH and SH3 domains.

Mouse (Murine) Formin Binding Protein 1 (FNBP1) interaction partners

  1. FBP17 interacts with dynamin and regulates endocytosis by forming vesicotubular structures.

Formin Binding Protein 1 (FNBP1) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin\; an interaction between this protein and formin has not been demonstrated yet in human.

Gene names and symbols associated with FNBP1

  • formin binding protein 1 (FNBP1) antibody
  • formin binding protein 1 (fnbp1) antibody
  • formin binding protein 1 (Fnbp1) antibody
  • formin binding protein 1 L homeolog (fnbp1.L) antibody
  • 1110057E06Rik antibody
  • 2210010H06Rik antibody
  • FBP1 antibody
  • Fbp17 antibody
  • MGC122623 antibody
  • MGC146466 antibody

Protein level used designations for FNBP1

formin binding protein 1 , formin-binding protein 1-like , formin-binding protein 1 , formin-binding protein 17 , formin binding protein 17 , rapostlin , formin-binding protein 1 homolog

GENE ID SPECIES
480695 Canis lupus familiaris
538717 Bos taurus
742858 Pan troglodytes
780119 Xenopus (Silurana) tropicalis
100015366 Monodelphis domestica
100154729 Sus scrofa
100386354 Callithrix jacchus
23048 Homo sapiens
14269 Mus musculus
192348 Rattus norvegicus
100069871 Equus caballus
444253 Xenopus laevis
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