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GPR61 belongs to the G-protein coupled receptor 1 family. Additionally we are shipping G Protein-Coupled Receptor 61 Proteins (4) and many more products for this protein.
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These data suggested that GPR61 colocalizes with GnRHR in the plasma membrane of gonadotrophs, and its expression changes stage-dependently in the bovine anterior pituitary gland.
Collectively, these data show that GPR61, GPR62 and GPR135 are unable to bind melatonin, but show a reciprocal regulatory interaction with MT2 receptors.
maps to chromosome 1, is widely expressed, with expression highest in the brain areas associated with cognition, learning, and memory.
Modeling rationalizes the effects of transmembrane proline mutants previously reported for another family of GPCR.
We conclude that the N-terminal domain of GPR61 is required for maintaining its constitutive activity and functions as a tethered intramolecular ligand.
These findings suggest that GPR61 is involved in the regulation of food intake and body weight
This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.
G protein-coupled receptor 61
, probable G-protein coupled receptor 61
, probable G-protein coupled receptor 61-like
, biogenic amine receptor-like G-protein coupled receptor
, biogenic amine receptor-like GPCR