anti-G Protein-Coupled Receptor 81 (GPR81) Antibodies

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.. Additionally we are shipping G Protein-Coupled Receptor 81 Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR81 243270  
GPR81 689936  
GPR81 27198 Q9BXC0
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Top anti-G Protein-Coupled Receptor 81 Antibodies at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of GPR81 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Bat Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: GPR81 Antibody [NLS2091] - Analysis of anti-FKSG80 / GPR81 antibody with pituitary, anterior at 3 ug/ ml. Immunohistochemistry-Paraffin: GPR81 Antibody [NLS2091] - Analysis of anti-FKSG80 / GPR81 antibody with human brain, glioblastoma. 0.05 mL Log in to see 10 to 13 Days
$514.63
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry: GPR81 Antibody [NLS2095] - Analysis of anti-FKSG80 / GPR81 antibody with pituitary. Immunohistochemistry-Paraffin: GPR81 Antibody [NLS2095] - Human Skin, Melanoma formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 0.05 mL Log in to see 10 to 13 Days
$514.63
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GPR81 Antibody (C-term) in 293 cell line lysates (35ug/lane). This demonstrates the GPR81 antibody detected the GPR81 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Goat Un-conjugated ELISA, WB Western Blot: GPR81 Antibody [NBP1-51956] - Analysis of GPR81 in Human Liver lysate (35ug protein in RIPA buffer) using NBP1-51956 at 0.5g/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human Colon, Epithelium (formalin-fixed, paraffin-embedded) stained with GPR81 antibody ABIN213369 at 11 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Bat Rabbit Un-conjugated IHC, IHC (p) Anti-GPR81 antibody  ABIN1048875 IHC staining of human pituitary, anterior. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-FKSG80 / GPR81 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-GPR81 antibody  ABIN1048876 IHC staining of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-FKSG80 / GPR81 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details

Top referenced anti-G Protein-Coupled Receptor 81 Antibodies

  1. Human Polyclonal GPR81 Primary Antibody for IHC (p) - ABIN4315865 : Jeninga, Bugge, Nielsen, Kersten, Hamers, Dani, Wabitsch, Berger, Stunnenberg, Mandrup, Kalkhoven: Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81). in The Journal of biological chemistry 2009 (PubMed)

  2. Human Polyclonal GPR81 Primary Antibody for ELISA, WB - ABIN4274870 : Cai, Ren, Jin, Cheng, Kash, Chen, Wright, Taggart, Waters: Role of GPR81 in lactate-mediated reduction of adipose lipolysis. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against G Protein-Coupled Receptor 81 Interaction Partners

Mouse (Murine) G Protein-Coupled Receptor 81 (GPR81) interaction partners

  1. lactate can induce GPR81-independent metabolic changes that modulate macrophage pro-inflammatory activation.

  2. GPR81 expression increased during gestation, and peaked near labor. GPR81 is expressed in the uterus with high expression in myometrium. GPR81 mediates inflammation in the laboring uterus.

  3. Results indicate that lactate may aggravated ischemic brain injury by activating GPR81 and inhibition of GPR81 protects against ischemia-induced cell death via an antiapoptosis pathway

  4. Description of a GPR81 selective agonist with in vivo efficacy, inhibiting lipolysis without flushing.

  5. Lactate negatively regulates TLR induction of the NLRP3 (show NLRP3 Antibodies) inflammasome and production of IL1beta (show IL1B Antibodies), via ARRB2 (show ARRB2 Antibodies) and GPR81 in liver and pancreatic injury.

  6. chronic obesity reduces GPR109A (show HCAR2 Antibodies) and GPR81 expression in the adipose tissue, while acute in vitro LPS (show TLR4 Antibodies) treatment increases expression of GPR109A (show HCAR2 Antibodies) in adipocytes and macrophages.

  7. Inflammation decreases the expression of GPR81 in adipose tissue

  8. An autocrine lactate loop mediates insulin (show INS Antibodies)-dependent inhibition of lipolysis through GPR81.

  9. GPR81 couples to the Gi signaling pathway

  10. Data show that siRNA-mediated knockdown (show PPARG Antibodies)of PPARgamma in differentiated 3T3-L1 adip (show HCAR2 Antibodies)ocytes showe (show HCAR3 Antibodies)d a significant decrease in Gpr81 protein expression.

Human G Protein-Coupled Receptor 81 (GPR81) interaction partners

  1. The novel role of HCAR1 in development of chemoresistance in cervical carcinoma HeLa cells via ABCB1 (show ABCB1 Antibodies) transporter up-regulation.

  2. Findings identify GPR81 as a tumor-promoting receptor in breast cancer progression and suggest a novel mechanism that regulates GPR81-dependent activation of the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling axis in tumor microenvironment.

  3. Activation of GPR81 decreases intracellular cAMP levels and inhibits PKA activity, leading to activation of TAZ (show TAZ Antibodies) and upregulation of PD-L1 (show CD274 Antibodies). This study reveals a critical role for lactate in the immune checkpoint pathway and an unexpected function of TAZ (show TAZ Antibodies) in tumor evasion of the T-cell-mediated immune response.

  4. Lactate receptor/HCAR1 expression in cervical carcinoma cells may contribute to the modulation of cellular DNA repair mechanisms.

  5. HCA1/3 are necessary for breast cancer cells to balance lipid/fatty acid metabolism.

  6. HCAR1 and monocarboxylate transporters activity is required for the L- and D-lactate-mediated enhancement of DNA repair and of HeLa cell survival.

  7. Description of a GPR81 selective agonist with in vivo efficacy, inhibiting lipolysis without flushing.

  8. Data support that GPR81 is important for cancer cell regulation of lactate transport mechanisms.

  9. Lactate negatively regulates TLR induction of the NLRP3 (show NLRP3 Antibodies) inflammasome and production of IL1beta (show IL1B Antibodies), via ARRB2 (show ARRB2 Antibodies) and GPR81 in liver and pancreatic injury.

  10. demonstrated that the C165-E166-S167-F168 motif at the second extracellular loop is critical for GPR81 function, and the conserved six Cys (show DNAJC5 Antibodies) residues at the extracellular regions are necessary for GPR81 function

G Protein-Coupled Receptor 81 (GPR81) Antigen Profile

Protein Summary

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.

Gene names and symbols associated with GPR81

  • hydroxycarboxylic acid receptor 1 (HCAR1) antibody
  • hydroxycarboxylic acid receptor 1-1 (hcar1-1) antibody
  • hydrocarboxylic acid receptor 1 (Hcar1) antibody
  • G protein-coupled receptor 81 (Gpr81) antibody
  • GPR81 antibody
  • gpr81-1 antibody
  • GPR104 antibody
  • HCA1 antibody
  • Hcar1 antibody
  • LACR1 antibody
  • TA-GPCR antibody

Protein level used designations for GPR81

G protein-coupled receptor 81 , G-protein coupled receptor 81 , hydroxycarboxylic acid receptor 1 , G protein-coupled receptor 104 , G-protein coupled receptor 104 , T-cell activation G protein-coupled receptor , hydroxy-carboxylic acid receptor 1 , lactate receptor 1

GENE ID SPECIES
452331 Pan troglodytes
538759 Bos taurus
570755 Danio rerio
702825 Macaca mulatta
100345808 Oryctolagus cuniculus
243270 Mus musculus
689936 Rattus norvegicus
486252 Canis lupus familiaris
27198 Homo sapiens
100153287 Sus scrofa
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