anti-GABA Transporter 1 (GAT1) Antibodies

The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]).[supplied by OMIM, Jul 2009].. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GAT1 6529 P30531
GAT1 50676 P48056
GAT1    
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Top anti-GABA Transporter 1 Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-SLC6A1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SLC6A1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IHC (p), WB Anti-GABA Transporter 1/GAT 1 antibody, IHC(P) IHC(P): Rat Brain Tissue Anti-GABA Transporter 1/GAT 1 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate 100 μg Log in to see 4 to 6 Days
$280.00
Details
Cow Rabbit Un-conjugated IP, WB Western blot analysis of GAT1 expression in SHSY5Y (A), NIH3T3 (B), rat brain (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated IHC (fro), WB   0.1 mL Log in to see 12 to 15 Days
$484.50
Details
Dog Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 7 to 9 Days
$415.44
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

GAT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
,

Rat (Rattus) ,
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Mouse (Murine) ,
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Top referenced anti-GABA Transporter 1 Antibodies

  1. Dog (Canine) Polyclonal GAT1 Primary Antibody for ELISA, WB - ABIN4273530 : de Krom, Staal, Ophoff, Hendriks, Buitelaar, Franke, de Jonge, Bolton, Collier, Curran, van Engeland, van Ree: A common variant in DRD3 receptor is associated with autism spectrum disorder. in Biological psychiatry 2009 (PubMed)

  2. Rat (Rattus) Polyclonal GAT1 Primary Antibody for ICC, IHC - ABIN1742535 : Aracri, Meneghini, Coatti, Amadeo, Becchetti: α4β2(∗) nicotinic receptors stimulate GABA release onto fast-spiking cells in layer V of mouse prefrontal (Fr2) cortex. in Neuroscience 2016 (PubMed)

More Antibodies against GABA Transporter 1 Interaction Partners

Human GABA Transporter 1 (GAT1) interaction partners

  1. the "extra" residue in transmembrane domain 10 of the GABA transporter GAT-1 provides extra bulk, probably in the form of a pi-helix, which is required for stringent gating and tight coupling of ion and substrate fluxes in the GABA transporter family.

  2. Results show that SLC6A1 minor genotypes/alleles were protective against risk for alcoholism in 3 ethnically diverse cohorts.

  3. Genome-wide significant associations were highly biological plausible, including associations within GABA transporter 1, SLC6A1 (solute carrier (show SERTAD2 Antibodies) family 6, member 1), and exonic hits in LOC100129340 (mitofusin-1 (show MFN1 Antibodies)-like

  4. targeted resequencing of 644 individuals with epileptic encephalopathies led to the identification of six SLC6A1 mutations in seven individuals, all of whom have epilepsy with myoclonic-atonic seizures (MAE).

  5. 3p25.3 microdeletion of GABA transporters SLC6A1 and SLC6A11 results in intellectual disability, epilepsy and stereotypic behavior.

  6. Cysteine mutagenesis of GAT-1 pointed to conformationally sensitive proximity of extracellular loops 2 and 4 in this protein.

  7. The aromatic and charge pairs of the thin extracellular gate of the GABA transporter GAT-1 are differently impacted by mutation.

  8. a functional interaction of the external and internal gates of GAT-1 is essential for transport

  9. TM10 of GAT-1 lines an accessibility pathway from the extracellular space into the binding pocket and plays a role in the opening and closing of the extracellular transporter gate.

  10. GABA Transporter Mutagenesis Database (GATMD), a web-accessible, relational database of manually annotated biochemical, functional and pharmacological data reported on GAT1.

GABA Transporter 1 (GAT1) Antigen Profile

Protein Summary

The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009

Gene names and symbols associated with GAT1

  • solute carrier family 6 member 1 (SLC6A1) antibody
  • solute carrier family 6 member 12 (Slc6a12) antibody
  • BGT1 antibody
  • GABATHG antibody
  • GABATR antibody
  • Gat1 antibody
  • RNU28927 antibody
  • VGAT antibody

Protein level used designations for GAT1

GABA transporter 1 , GAT-1 , sodium- and chloride-dependent GABA transporter 1 , solute carrier family 6 (neurotransmitter transporter, GABA), member 1 , solute carrier family 6 member 1 , Betaine/GABA transporter 1 , Na(+)/Cl(-) betaine/GABA transporter , sodium- and chloride-dependent betaine transporter , solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 , solute carrier family 6 member 12 , vesicular GABA transporter

GENE ID SPECIES
6529 Homo sapiens
50676 Rattus norvegicus
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