anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) Antibodies

The protein encoded by GEM belongs to the RAD/GEM family of GTP-binding proteins.

list all antibodies Gene Name GeneID UniProt
Anti-Human GEM GEM 2669 P55040
Anti-Rat GEM GEM 297902  
Anti-Mouse GEM GEM 14579 P55041
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Top anti-GEM Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GEM Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-GEM Antibody Titration:  2.5ug/ml  Positive Control:  HepG2 cell lysate Rabbit Anti-GEM Antibody  Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), WB Western Blot: GEM Antibody [NBP1-58906] - Sample Tissue: Human Stomach Tumor Antibody Dilution: 1.0 ug/ml Western Blot: GEM Antibody [NBP1-58906] - Titration: 2.5ug/ml Positive Control: HepG2 cell lysate. 100 μL Log in to see 8 to 11 Days
$444.19
Details
Human Goat Un-conjugated ELISA, WB Western Blot: GEM Antibody [NBP2-26121] - (1ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: GEM Antibody [NBP2-26121] - HEK293 lysate overexpressing full-length Human GEM (HA tagged), mock-transfected HEK293 (EV) and HEK293 transiently expressing GEM-related genes (Rem, Rem2L and Rad) probed with NBP2-26121 (1ug/ml). The same lysates probed with anti-HA tag antibody in the lower panel. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE antibody diluted at 1:500 IHC-P Image GEM antibody [N1], N-term detects GEM protein at membrane on human lung by immunohistochemical analysis. Sample: Paraffin-embedded lung. GEM antibody [N1], N-term , dilution: 1:500. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: GEM Antibody [NBP1-30962] - Paraffin-embedded lung; antibody dilution 1:500. Western Blot: GEM Antibody [NBP1-30962] - Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE, antibody diluted at 1:500. 100 μL Log in to see 8 to 11 Days
$514.63
Details

Top referenced anti-GEM Antibodies

  1. Human Polyclonal GEM Primary Antibody for ICC, IF - ABIN4313837 : Laurberg, Jensen, Schepeler, Borre, Ørntoft, Dyrskjøt: High expression of GEM and EDNRA is associated with metastasis and poor outcome in patients with advanced bladder cancer. in BMC cancer 2014 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal GEM Primary Antibody for ELISA, WB - ABIN4313839 : Wang, Johnston, Chou, Dean: A systemic network for Chlamydia pneumoniae entry into human cells. in Journal of bacteriology 2010 (PubMed)

More Antibodies against GEM Interaction Partners

Human GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) interaction partners

  1. High Geminin (show GMNN Antibodies) expression is associated with triple negative breast cancers.

  2. these data identify DUB3 (show USP17L2 Antibodies) and USP7 (show USP7 Antibodies) as factors that regulate DNA replication by controlling Geminin protein (show GMNN Antibodies) stability, and suggest that USP7 (show USP7 Antibodies) may be involved in Geminin (show GMNN Antibodies) dysregulation during breast cancer progression.

  3. geminin (show GMNN Antibodies) selectively couples the transcription factor forkhead box O3 (FoxO3 (show FOXO3 Antibodies)) to HDAC3 (show HDAC3 Antibodies), thereby specifically facilitating FoxO3 (show FOXO3 Antibodies) deacetylation.

  4. summarize current information on the molecular functions of Geminin (show GMNN Antibodies) and the regulatory system for Geminin protein (show GMNN Antibodies) expression, and argue for the molecular role of Geminin (show GMNN Antibodies) in cell fate determination of hematopoietic stem cells [review]

  5. Down regulation of Gem expression was involved in the pathogenesis of hepatocellular carcinoma (HCC (show FAM126A Antibodies)), and it might be a favorable independent prognostic parameter for HCC (show FAM126A Antibodies).

  6. Studies indicate that geminin (show GMNN Antibodies) expression is associated with different types of cancer.

  7. High geminin (show GMNN Antibodies) expression is associated with breast cancer.

  8. De novo GMNN (show GMNN Antibodies) mutations cause autosomal-dominant primordial dwarfism associated with Meier-Gorlin syndrome.

  9. Elevated Ki67 (show MKI67 Antibodies) and geminin (show GMNN Antibodies) expression distinguish a fraction of metastatic breast carcinoma with worse prognosis.

  10. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages.

Mouse (Murine) GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) interaction partners

  1. Rad (show RRAD Antibodies), Gem and Rem (show REM1 Antibodies) all reduce depolarization-dependent Ca2 (show CA2 Antibodies)+ entry in developing myotubes.

  2. These results suggest that Gem plays an important role in normal beta-cell function by regulation of calcium signalling.

  3. Mechanism of the inhibition of calcium channel activity by Gem.

  4. docking of the RGK protein to the nucleotide-kinase domain of the Cavbeta subunit is reminiscent of the binding of GMP (show NT5C2 Antibodies) to guanylate kinase (show GUK1 Antibodies)

  5. Results identify specific nuclear localization signals (NLS (show ALDH1A2 Antibodies)) in Kir/Gem that are both required and sufficient for nuclear transport.

GEM Antigen Profile

Protein Summary

This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.

Gene names and symbols associated with GEM

  • GTP binding protein overexpressed in skeletal muscle (GEM) antibody
  • GTP binding protein overexpressed in skeletal muscle (gem) antibody
  • GTP binding protein overexpressed in skeletal muscle (Gem) antibody
  • geminin, DNA replication inhibitor (GMNN) antibody
  • GTP binding protein (gene overexpressed in skeletal muscle) (Gem) antibody
  • AV020497 antibody
  • DKFZp470D0612 antibody
  • Gem antibody
  • kir antibody
  • LOC100221129 antibody
  • xgem antibody
  • zgc:153003 antibody

Protein level used designations for GEM

GTP-binding mitogen-induced T-cell protein , GTP-binding protein GEM , GTP-binding protein overexpressed in skeletal muscle , RAS-like protein KIR , kinase-inducible Ras-like protein , GTP binding protein overexpressed in skeletal muscle , Gem GTPase , GTP binding protein gene overexpressed in skeletal muscle , GTP binding protein (gene overexpressed in skeletal muscle) , geminin

GENE ID SPECIES
2669 Homo sapiens
100173856 Pongo abelii
404771 Gallus gallus
699130 Macaca mulatta
738628 Pan troglodytes
538437 Bos taurus
404772 Sus scrofa
100221129 Taeniopygia guttata
100038040 Xenopus (Silurana) tropicalis
560566 Danio rerio
297902 Rattus norvegicus
51053 Homo sapiens
14579 Mus musculus
611634 Canis lupus familiaris
100716695 Cavia porcellus
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