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Receptor for gastrin releasing peptide (GRP). Additionally we are shipping GRPR Kits (6) and GRPR Proteins (6) and many more products for this protein.
Showing 10 out of 66 products:
Bat Polyclonal GRPR Primary Antibody for IHC (p), WB - ABIN271325
Grimsholm, Rantapää-Dahlqvist, Dalén, Forsgren et al.: Observations favouring the occurrence of local production and marked effects of bombesin/gastrin-releasing peptide in the synovial tissue of the human knee joint--comparisons with substance P and the ... in Neuropeptides 2008
Show all 2 Pubmed References
These data suggest that GRPR expression in fibroblast-like synoviocytes (FLS)and that exogenous GRP are able to activate FLS invasion. This effect occurs at least in part through the AKT activation. Therefore, understanding of the GRP/GRPR pathway could be relevant in the development of FLS-targeted therapy for Rheumatoid arthritis .
ablating GRP (show UCMA Antibodies) receptor-expressing neurons eliminated basal and hypoxia-induced sighing, but left breathing otherwise intact initially
Together, we define the respective function of NMBR (show NMBR Antibodies) and GRPR in itch transmission, and reveal an unexpected relationship not only between the two receptors but also between the two populations of interneurons in itch signaling.
BNP (show BNC2 Antibodies)-NPRA (show NPR1 Antibodies) signaling is involved in both itch and pain and does not function upstream of the GRP (show UCMA Antibodies)-GRPR dedicated neuronal pathway.
The present results suggest that BB2 receptor-expressing spinal neurons transmit herpes-associated itch by BB2 receptor-independent signaling.
spinal GRPr and NMBr (show NMBR Antibodies) independently drive itch neurotransmission in mice.
GRPR and stathmin (show STMN1 Antibodies) control in opposite directions both cued fear extinction and neural activities of the amygdala and prefrontal cortex
Gastrin-releasing peptide receptor mediates chemotaxis in neutrophils, and may be an alternative chemotactic receptor playing a role in the pathogenesis of inflammatory disorders.
The data suggest that opioid-induced itch is an active process concomitant with but independent of opioid analgesia, occurring via the unidirectional cross-activation of GRPR signaling by MOR1D heterodimerization
We propose that deletion of GRPR leads to the induction of depression-like behavior which is paralleled by dysregulation of amygdala gene expression, potentially resulting from deficient light-induced corticosterone release in GRPR-knockout mice
GRP/GRP (show LSM4 Antibodies)-R signaling activation contributes to castration-resistant prostate cancer progression
Expression of Gastrin-Releasing Peptide Receptor in Breast Cancer and Its Association with Pathologic, Biologic, and Clinical Parameters
Our results suggest that, similar to what happens in neutrophils, gastrin-releasing peptide (show GRP Antibodies) is a migratory, rather than a proliferative, stimulus, for non-small cell lung carcinoma cells, indicating a putative role for gastrin-releasing peptide (show GRP Antibodies) and gastrin-releasing peptide receptor in metastasis
GRP-R regulates glucose metabolism in neuroblastoma (show ARHGEF16 Antibodies) by modulating HIF-1alpha (show HIF1A Antibodies), PDK4 (show PDK4 Antibodies) and PDP2 (show PDP2 Antibodies).
BBS (show BBS2 Antibodies) caused a significant increase in Shh (show SHH Antibodies) gene transcription and protein secretion that was dependent on BBS (show BBS2 Antibodies)-induced GPCR (show NMUR1 Antibodies)/Galphaq (show GNAQ Antibodies)-//Rho mediated activation of nuclear factor kappaB (NFkappaB (show NFKB1 Antibodies)), which can stimulate a NF-kappaB (show NFKB1 Antibodies) response element in the Shh (show SHH Antibodies) gene promoter
No association of 16 GRP (show LSM4 Antibodies) and 7 GRPR variants were found with agoraphobia with/without panic disorder.
GRPR is highly expressed in epidermoid carcinoma of the anal canal, suggesting this receptor might have a role in anal carcinogenesis.
a key mechanism for GRPR-regulated colon cancer cell migration through the Galpha13 (show GNA13 Antibodies)-PRG (show PRB3 Antibodies)-RhoA (show RHOA Antibodies)-ROCK pathway.
GRPR expression was more pronounced in an advanced-stage lung cancer
integrin ss1 subunit critically regulates GRP-R-mediated neuroblastoma (show ARHGEF16 Antibodies) cell migration and invasion
Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
gastrin-releasing peptide receptor
, gastrin-releasing peptide receptor-like
, GRP-preferring bombesin receptor
, bombesin receptor