anti-Glial Fibrillary Acidic Protein (GFAP) Antibodies

GFAP encodes one of the major intermediate filament proteins of mature astrocytes. Additionally we are shipping GFAP Kits (83) and GFAP Proteins (38) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GFAP 2670 P14136
Anti-Rat GFAP GFAP 24387 P47819
Anti-Mouse GFAP GFAP 14580 P03995
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Top anti-GFAP Antibodies at antibodies-online.com

Showing 10 out of 984 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Anti-GFAP Picoband antibody,  IHC(P): Human meningioma Tissue Anti-GFAP Picoband antibody,  IHC(P): Rat Brain Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Cat Rabbit Un-conjugated IEM, ICC, IF, IHC IHC image of astrocytes in rat cortex. 6 mL Log in to see 2 to 3 Days
$206.25
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-GFAP antibody, IHC(P) IHC(P): Rat Brain Tissue Anti-GFAP antibody, Western blotting All lanes: Anti GFAP at 0.5ug/ml Lane 1: Rat Brain Tissue Lysate at 50ug Lane 2: Mouse Brain Tissue Lysate at 50ug Lane 3: U87 Whole Cell Lysate at 40ug Predicted bind size: 49KD Observed bind size: 49KD 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Mouse Un-conjugated IHC (fro), IHC (p), WB Anti- GFAP antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Cat Rabbit Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), SimWes, WB Staining of typical astrocytic cells using ABIN152487 in neurons and glia of rat forebrain. Immunocytochemistry/Immunofluorescence: GFAP Antibody [ABIN152487] - Xenografted mouse brain section : astocyte and human nuclei. Image from a confirmed customer review. 0.05 mL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated FACS, IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded: rat brain tissue Anti-GFAP Polyclonal Antibody, Unconjugated (ABIN726200) at 1:400, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded: human placenta tissue labeled with Anti-GFAP Polyclonal Antibody, Unconjugated (ABIN726200) at 1:800, followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Goat Un-conjugated ELISA, WB ABIN185730 (0.03µg/ml) staining of Mouse Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185730 (5 µg/mL) as the reporter with EB002015 as the capture rabbit antibody (5 µg/mL). Please note this data was obtained using a previous batch. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: GFAP Antibody [NBP2-33774] - Staining of human hippocampus shows strong immunoreactivity in astrocytes. Immunocytochemistry/Immunofluorescence: GFAP Antibody [NBP2-33774] - Staining of mouse rostral migratory stream shows selective positivity in a subset of processes. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Mouse Un-conjugated IF, WB 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Cow Rabbit Un-conjugated IHC, WB Sample Type: human optic nerve head (frozen)Blue: DAPIRed: GfapPrimary Dilution: 1:250Image Submitted By: Geraint ParfittGavin Herbert Eye Institute . 100 μL Log in to see 2 to 3 Days
$319.00
Details

Top referenced anti-GFAP Antibodies

  1. Cat (Feline) Polyclonal GFAP Primary Antibody for IEM, ICC - ABIN789007 : Segal, Takahashi, McKay: Changes in neurotrophin responsiveness during the development of cerebellar granule neurons. in Neuron 1993 (PubMed)
    Show all 199 Pubmed References

  2. Human Polyclonal GFAP Primary Antibody for IHC (p), WB - ABIN3043832 : Lu, Yuan, Ou, Cai, Wang, Sun, Zhang: Autophagy and apoptosis during adult adipose-derived stromal cells differentiation into neuron-like cells in vitro. in Neural regeneration research 2015 (PubMed)
    Show all 82 Pubmed References

  3. Human Polyclonal GFAP Primary Antibody for IHC (p), WB - ABIN3044350 : Zhou, Wang, Li, Wang, Wu, Zhang: Paeoniflorin attenuates the neuroinflammatory response in a rat model of chronic constriction injury. in Molecular medicine reports 2017 (PubMed)
    Show all 80 Pubmed References

  4. Human Monoclonal GFAP Primary Antibody for IHC (fro), IHC (p) - ABIN3043647 : Zhao, Guo, Li, Zang, Qu, Zhou, Li, Sun: Amelioration of dementia induced by A? 22-35 through rectal delivery of undecapeptide-hEGF to mouse brain. in International journal of pharmaceutics 2011 (PubMed)
    Show all 79 Pubmed References

  5. Cat (Feline) Polyclonal GFAP Primary Antibody for ICC, IF - ABIN152487 : Henion, Qu, Smith: Expression of dystroglycan, fukutin and POMGnT1 during mouse cerebellar development. in Brain research. Molecular brain research 2003 (PubMed)
    Show all 35 Pubmed References

  6. Mammalian Monoclonal GFAP Primary Antibody for ISt, IHC - ABIN1304664 : Savic, Stojiljkovic, Lavrnja, Parabucki, Bjelobaba, Nedeljkovic, Herdegen, Pekovic: Ribavirin shows immunomodulatory effects on activated microglia. in Immunopharmacology and immunotoxicology 2014 (PubMed)
    Show all 19 Pubmed References

  7. Human Polyclonal GFAP Primary Antibody for FACS, IF (cc) - ABIN726200 : Zhao, Zhao, Wang, Xu, Miao, Feng, Chen, Kovács, Fan, Zhang: Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration. in The Journal of cell biology 2013 (PubMed)
    Show all 16 Pubmed References

  8. Chicken Polyclonal GFAP Primary Antibody for ICC, IP - ABIN1742363 : Christensen, Schneider-Axmann, Lucassen, Bayer, Wirths: Accumulation of intraneuronal Abeta correlates with ApoE4 genotype. in Acta neuropathologica 2010 (PubMed)
    Show all 13 Pubmed References

  9. Bird (Avian) Monoclonal GFAP Primary Antibody for ICC, IF - ABIN446355 : Brai, Marathe, Zentilin, Giacca, Nimpf, Kretz, Scotti, Alberi: Notch1 activity in the olfactory bulb is odour-dependent and contributes to olfactory behaviour. in The European journal of neuroscience 2014 (PubMed)
    Show all 7 Pubmed References

  10. Human Monoclonal GFAP Primary Antibody for ICC, IHC (p) - ABIN457420 : Bignami, Eng, Dahl, Uyeda: Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence. in Brain research 1972 (PubMed)
    Show all 6 Pubmed References

More Antibodies against GFAP Interaction Partners

Rhesus Monkey Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. There was significantly more GFAP immunoreactivity in the prefrontal cortex and hippocampus of aged animals compared to adult or middle-aged animals.

Human Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. serum level not significantly elevated in newborns at risk for hypoxic ischemic encephalopathy but with normal EEGs

  2. crystal structure of human GFAP spanning the central coiled-coil 1B domain at 2.5A resolution

  3. GFAP levels are a novel and complementary biomarker to predict functional outcome 1 year after acute ischemic stroke.

  4. The features of the neuropathology and immunopathology of GFAP astrocytopathies were perivascular inflammation and loss of astrocytes and neurons

  5. amniotic fluid -GFAP levels differentiate between myelomeningocele and myeloschisis, and raise interesting questions regarding the clinical significance between the 2 types of defects.

  6. Desmin, Glial Fibrillary Acidic Protein, Vimentin, and Peripherin are type III intermediate filaments that have roles in health and disease [review]

  7. Plasma concentration of GFAP demonstrated associations with stroke occurrence in a West African cohort but was not associated with stroke severity or mortality.

  8. This study demonstrated that Concentrations of microparticles expressing GFAP and AQP4 were significantly higher in the traumatic brain injury group compared with healthy controls.

  9. The authors observed higher serum levels of GFAP and UCH-L1 in brain-injured children compared with controls and also demonstrated a step-wise increase of biomarker concentrations over the continuum of severity from mild to severe traumatic brain injury. Serum UCH-L1 and GFAP concentrations also strongly predicted poor outcome.

  10. Study examined if QKI6B expression can predict the outcome of GFAP, and several oligodendrocyte-related genes, in the prefrontal cortex of brain samples of schizophrenic individuals. QKI6B significantly predicts the expression of GFAP, but does not predict oligodendrocyte-related gene outcome, as previously seen with other QKI isoforms.

  11. GFAP, along with tau and AmyloidBeta42, were increased in plasma up to 90 days after traumatic brain injury compared with controls.

  12. Results show that the positive rates and expression levels of nestin, tyrosine hydroxylase (TH), GFAP and IL-17 were significantly decreased while Foxp3 and the ratio of Foxp3/IL-17 were statistically elevated in BM of AML patients.

  13. GFAP levels >0.29 ng/ml were seen only in intracerebral hemorrhage, thus confirming the diagnosis of ICH during prehospital care.

  14. These results indicate that autoantibodies against GFAP could serve as a predictive marker for the development of overt autoimmune diabetes.

  15. Higher median plasma GFAP values were documented in intracerebral hemorrhage compared with acute ischemic stroke, stroke mimics, and controls.

  16. GFAP is specifically expressed in the auricular chondrocytes, and assumes a pivotal role in resistance against mechanical stress.

  17. Bevacizumab treatment was also associated with structural protein abnormalities, with decreased GFAP and vimentin content and upregulated GFAP and vimentin mRNA expression.

  18. the exchange of GFP-GFAPdelta was significantly slower than the exchange of GFP-GFAPalpha with the intermediate filament-network.

  19. Tat expression or GFAP expression led to formation of GFAP aggregates and induction of unfolded protein response (UPR) and endoplasmic reticulum (ER) stress in astrocytes.

  20. This study demonstrated that GFAP exhibited distinct temporal profiles over the course of 7 days in patient with traumatic brain injury.

Pig (Porcine) Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. Isolation of an evolutionary conserved novel GFAP isoform, GFAPkappa, produced by alternative splicing and polyadenylation of the 3'-region of the human GFAP pre-mRNA is described.

Mouse (Murine) Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. Study demonstrated that protein citrullination, along with upregulation and an increase in peptidylarginine deiminase, occur in a widely used bile duct ligation (BDL) mouse model of hepatic fibrosis. Expression level of GFAP and the amount of cit-GFAP were higher in BDL livers than in control livers. In correlation with PAD2 localization, cit-GFAP was observed in alpha-SMA-positive and CK19-positive cells in the livers.

  2. The results indicate that finely tuned levels of Lmnb1 are required for neural stem cells differentiation into neurons, proper expression of the astrocytic marker GFAP and corticogenesis.

  3. The results suggest that BRG1 and STAT3 coordinately regulate gene clustering and up-regulate Gfap and Osmr transcription in astrocytes.

  4. This report the successful prediction and validation of Gfap as an miR-3099 target gene using a combination of bioinformatics resources with enrichment of annotations based on functional ontologies and a spatio-temporal expression dataset.

  5. These results indicate that autoantibodies against GFAP could serve as a predictive marker for the development of overt autoimmune diabetes.

  6. GFAP is specifically expressed in the auricular chondrocytes, and assumes a pivotal role in resistance against mechanical stress.

  7. compared open-skull and thinned-skull imaging methods for two-photon laser microscopy of live astrocytes in neocortex of GFAP-GFP transgenic mice

  8. work reveals that an Alexander disease-causing mutation alters GFAP turnover kinetics in vivo and provides an essential foundation for future studies aimed at preventing or reducing the accumulation of GFAP.

  9. Tat expression or GFAP expression led to formation of GFAP aggregates and induction of unfolded protein response (UPR) and endoplasmic reticulum (ER) stress in astrocytes.

  10. Study provides evidence that transcription of one of the astrocyte-specific genes, Gfap, is cooperatively regulated by co-expressed genes and their regulatory factors.

  11. This study demonstrated the GFAP-ApoE4 mice exhibited motor impairments when compared to GFAP-ApoE3 and wild-type mice.

  12. PINK1 deficiency causes defects in GFAP-positive astrogliogenesis during brain development.

  13. Gnasxl deficiency does not directly affect glial development in the hypothalamus, since it is expressed in neurons, and Gfap-positive astrocytes and tanycytes appear normal during early postnatal stages.

  14. Induction of glial cytokine expression was sequential, aligned with active sickness behavior, and preceded increased Iba-1 or GFAP immunoreactivity after lipopolysaccharide challenge

  15. Study provides a mechanistic link between the GFAP mutations/overexpression and the symptoms in those affected with Type II Alexander disease

  16. Study described GFAP-expressing non-myelinating Schwann cells in the lung, validated a transgenic mouse line that drives expression of cre under a GFAP promoter

  17. findings thus show that the inability to produce GFAP and Vim affects normal retinal physiology and that the effect of IF deficiency on retinal cell survival differs, depending on the underlying pathologic condition

  18. CUL4B as a negative regulator of GFAP expression during neural development.

  19. Astrocytes deficient of GFAP and vimentin showed decreased Notch signal sending competence and altered expression of Notch signaling pathway-related genes

  20. Absence of GFAP, or both GFAP and vimentin, alters Alzheimer's disease-induced changes in gene expression profile of astrocytes, showing a compensation of the decrease of neuronal support genes and a trend for a higher inflammatory expression profile

Zebrafish Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. Aggregation-prone GFAP mutation in Alexander disease was validated using a zebrafish model; The p.Asp128Asn GFAP mutation is likely to be a disease-causing mutation

  2. The distribution of GFAP immunoreactivity implies that enteric glia are widespread in the fish gastrointestinal tract.

  3. Generation of transgenic zebrafish that express green fluorescent protein (GFP) in glial cells driven by the zebrafish glial fibrillary acidic protein (GFAP) regulatory elements.

  4. Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2, undergo proliferation, and are capable of self-renewal within the matrix of distinct thickness in the telencephalon.

GFAP Antigen Profile

Protein Summary

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with GFAP

  • glial fibrillary acidic protein (GFAP) antibody
  • glial fibrillary acidic protein (LOC100136168) antibody
  • glial fibrillary acidic protein (gfap) antibody
  • glial fibrillary acidic protein (Gfap) antibody
  • AI836096 antibody
  • cb345 antibody
  • etID36982.3 antibody
  • GFAP antibody
  • gfapl antibody
  • wu:fb34h11 antibody
  • wu:fk42c12 antibody
  • xx:af506734 antibody
  • zgc:110485 antibody

Protein level used designations for GFAP

glial fibrillary acidic protein , glial fibrillary acidic protein alpha , intermediate filament , intermediate filament protein , zrf-1 antigen

GENE ID SPECIES
712941 Macaca mulatta
454741 Pan troglodytes
100136168 Oncorhynchus mykiss
100534495 Oreochromis niloticus
2670 Homo sapiens
24387 Rattus norvegicus
100720409 Cavia porcellus
101081938 Felis catus
396562 Sus scrofa
281189 Bos taurus
14580 Mus musculus
100352532 Oryctolagus cuniculus
419969 Gallus gallus
480495 Canis lupus familiaris
443220 Ovis aries
30646 Danio rerio
100172719 Pongo abelii
100033970 Equus caballus
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