anti-Granulysin (GNLY) Antibodies

The product of GNLY is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. Additionally we are shipping Granulysin Kits (28) and Granulysin Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNLY 10578 P22749
GNLY 404173  
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Top anti-Granulysin Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GNLY Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human Muscle 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB GNLY Antibody (N-term) (ABIN656999) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the GNLY antibody detected the GNLY protein (arrow). 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in MDA-MB435 cell line lysates (35 ug/lane) using GNLY Antibody (C-term) Cat.-No. AP51884PU-N. This demonstrates the GNLY antibody detected the GNLY protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse PE FACS 100 Tests 11 to 14 Days
$537.17
Details
Human Mouse Un-conjugated FACS 2 mL 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human larynx labeled with Rabbit Anti-GNLY/NKG5 Polyclonal Antibody, Unconjugated (ABIN742320) at 1:200 followed by conjugation to the secondary antibody and DAB staining paraformaldehyde-fixed, paraffin embedded human laryngocarcinoma tissue; Antigen retrieval with 0.01M citrate buffer(pH6) boiling for 15 minutes; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with Rabbit Anti-GNLY/NKG5 Polyclonal Antibody, Unconjugated  at 1:200 overnight at 4°C, followed by a conjugated secondary and DAB staining 100 μL 3 to 7 Days
$317.90
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged GNLY is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of GNLY expression in transfected 293T cell line by GNLY MaxPab polyclonal antibody.Lane 1: GNLY transfected lysate(15.95 KDa).Lane 2: Non-transfected lysate. 50 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL 11 to 13 Days
$335.04
Details

More Antibodies against Granulysin Interaction Partners

Human Granulysin (GNLY) interaction partners

  1. These studies provide a deeper insight into the subcellular localization and release mechanisms of the individual GNLY species.

  2. Increased seminal granulysin has a negative impact on spermatogenesis in infertile men in general and in infertility associated with varicocele in particular.

  3. The results suggest granulysin as a novel marker for a subset of cytotoxic natural killer cell derived malignancies

  4. These results suggest that the 15 kDa granulysin exhibits a novel mechanism in bacteria killing in a way that's different from most antimicrobial peptides.

  5. Decreased blood granulysin at the protein level, is linked to the immunological condition of latent tuberculosis infection.

  6. Carbamate pesticides significantly reduced the intracellular levels of perforin, GrA, GrB, Gr3/K, and GRN in NK-92CI cells.

  7. serum GNLY is closely associated with the clinical characteristics of nasopharyngeal carcinoma and may be a potential biomarker for nasopharyngeal carcinoma

  8. GNLY delivers Gzms into three protozoan parasites (Trypanosoma cruzi, Toxoplasma gondii and Leishmania major), in which the Gzms generate superoxide and inactivate oxidative defense enzymes to kill the parasite.

  9. Studies indicate that cytotoxic mechanisms mediated by granulysin and TRAIL (TNF-related apoptosis inducing ligand) seem to be less secondary effects on normal tissues.

  10. High Granulysin expression is associated with Cutaneous T Cell Lymphoma and Sezary Syndrome.

  11. A three-way interaction between SNPs in HLA-DQ and GNLY was identified in terms of HBV clearance.

  12. GNLY-expressing lymphocytes, probably attracted by IL-15, not only participate partially in myocardial cell apoptosis, but also hasten resolution of cardiac leukocyte infiltration in patients with myocardial infarction.

  13. Peptides encoded by this gene display antimicrobial activity against S. typhimurium, L. monocytogenes, E. coli, S. aureus, C. neoformans, C. albicans, L. major, and M. tuberculosis.

  14. Serum granulysin levels were significantly elevated in both acute and chronic alopecia areata patients.

  15. Human, but not rodent, cytotoxic granules also contain granulysin, an antimicrobial peptide in addition to granzymes; study shows that granulysin delivers granzymes into bacteria to kill diverse bacterial strains.

  16. It was concluded taht granulysin induces apoptosis on hematological tumor cells and on cells from B-cell lymphocytic leukemia patients, opening the door to research on its use as a new anti-tumoral treatment.

  17. suggested that the alteration of circulating granulysin has potential function in host immune response against TB and HIV/TB coinfection

  18. study to determine: expression of GNLY at the gene and protein levels at the maternal-fetal interface, relationship(s) between GNLY and perforin, and GNLY secretion by stimulated NK cells

  19. Granulysin is closely associated with the characteristics of NK-cell neoplasms and serum granulysin may serve as a novel biomarker for these disorders.

  20. GNLY polymorphism genotypes and diplotypes were associated with the chronicity of HBV

Cow (Bovine) Granulysin (GNLY) interaction partners

  1. Intercaruncular epithelium granulysin may play important roles in the establishment and maintenance of gestation during normal pregnancy.

Granulysin (GNLY) Antigen Profile

Protein Summary

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with anti-Granulysin (GNLY) Antibodies

  • granulysin (GNLY) antibody
  • 519 antibody
  • D2S69E antibody
  • LAG-2 antibody
  • LAG2 antibody
  • NKG5 antibody
  • TLA519 antibody

Protein level used designations for anti-Granulysin (GNLY) Antibodies

granulysin , T-cell activation protein 519 , T-lymphocyte activation gene 519 , lymphocyte-activation gene 2 , lymphokine LAG-2

GENE ID SPECIES
459370 Pan troglodytes
100125622 Ovis aries
10578 Homo sapiens
404173 Bos taurus
Selected quality suppliers for anti-Granulysin (GNLY) Antibodies
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