anti-Growth Arrest-Specific 1 (GAS1) Antibodies

Growth arrest-specific 1 plays a role in growth suppression. Additionally we are shipping GAS1 Kits (8) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GAS1 2619 P54826
GAS1 14451 Q01721
GAS1 683470  
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Top anti-GAS1 Antibodies at

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of NCI-H460 cells using GAS1 Antibiody (N-term) Cat.-No AP51781PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of GAS1 Antibody (N-term) Cat.-No AP51781PU-N with NCI-H460 cell followed by Alexa Fluor®488-conjugated Goat anti-Rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL 6 to 8 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from MCF-7 cells, using GAS1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6275166 staining MCF7 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL 11 to 12 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-Gas1 Polyclonal Antibody, Unconjugated (ABIN872751) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL 3 to 7 Days
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis in NCI-H460 cell line lysates (35ug/lane). GAS1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
Human Rabbit Un-conjugated ELISA, WB   100 μL Available
Human Rabbit Un-conjugated WB Western blot (WB) analysis of Gas1 antibody in extracts from MCF-7 cells. 0.1 mg 6 to 8 Days
Human Rabbit Alexa Fluor 594 IF (p)   100 μL 14 to 21 Days
Human Rabbit Un-conjugated ELISA, WB   100 μg 2 to 3 Days
Human Rabbit Un-conjugated ELISA, WB 200 μL 12 to 14 Days

More Antibodies against GAS1 Interaction Partners

Human Growth Arrest-Specific 1 (GAS1) interaction partners

  1. t is relevant to investigate the potential additive effect of the overexpression of GAS1 and PTEN on tumor growth. In particular, we employed secreted forms of both GAS1 (tGAS1) and PTEN (PTEN-LONG, or PTEN-L) and tested their combined effect on glioma cells.

  2. Studies establish Gas1 as a negative regulator in colorectal cancer.

  3. These results demonstrated that miR-184 and the GAS1/Akt pathway may be a potential therapeutic target for intervertebral disc degeneration.

  4. WT1 modulates Akt/JNK signaling pathway mediated autophagy by controlling the expression of growth arrest-specific 1 (Gas1).

  5. Downregulation of GAS1 is associated with clear cell renal cell carcinoma.

  6. the synergistic effect of Gas1 inhibition and GDNF against glutamate-induced cell injury in human SH-SY5Y neuroblastoma cells, is reported.

  7. solutions structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1

  8. This review summarizes the structure of Gas1 and molecular mechanism of action during embryonic development and cellular functions.

  9. GAS1 is a novel endogenous inhibitor of glomerular mesangial cell proliferation.

  10. Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer.

  11. GAS1 induced the activity of caspase-3 and resulting in apoptosis of the cells.

  12. Interference of endoplasmic reticulum to Golgi transport increased immature amyloid beta protein precursor accumulation upon Gas1 expression in lipid raft fractions.

  13. we demonstrate that sequence variants in GAS1 can impair its physical interaction with SHH, suggesting a decrease in the SHH downstream signaling cascade as a pathogenic mechanism of disease.

  14. Gas1 is a novel APP-interacting protein involved in the control of APP maturation and processing.

  15. Growth arrest-specific gene 1 contributes to predicting metastasis or recurrence in stage II and III colorectal cancer.

  16. GAS1 could be considered a candidate locus for one of the types of human holoprosencephaly.

  17. Gas1 is related to the GDNF alpha receptors and regulates Ret signaling

  18. This review considers the possible involvement of GAS1 in genetic diseases, stem cell renewal, and cancer growth through its cooperative activity with Hedgehog (HH) growth factor and the HH receptor.

  19. Gas1 is a molecule involved in cell arrest that can induce apoptosis when over-expressed in different cell lines.

  20. Gas1 has all the expected properties of a melanoma tumor suppressor: suppression of metastasis in a spontaneous metastasis assay, promotion of apoptosis following dissemination of cells to secondary sites, and down-regulation in human melanoma metastasis.

Mouse (Murine) Growth Arrest-Specific 1 (GAS1) interaction partners

  1. we demonstrated that Anxa1, Anxa2, and Dyrk1b are upregulated at both the transcriptional and translational levels by the overexpression of GAS1

  2. that Gas1 is a direct target of NeuroD1 during the induction of the neurogenic program

  3. Gas1 is expressed and released by neurons and promotes differentiation

  4. Western blot and immunofluorescence analyses showed two GIP-anchored proteins were clearly involved in the fertilisation process, namely growth arrest specific 1 (Gas1) and glial cell line-derived neurotrophic factor receptor alpha1 (Gfralpha1). This was demonstrated by evaluating oocyte fertilisability after treatment of oocytes with antibodies against the selected proteins, with their respective short interference RN...

  5. Findings provide evidence for a dual requirement for Boc and Gas1 during early development of the palate, mediating cell cycle regulation during growth and subsequent fusion of the palatal shelves.

  6. The results suggest that in diabetes the decrease of Gas1 promotes the activation of parietal progenitor cells of Bowman's capsule that might differentiate into podocytes and compensate their loss observed in this pathology.

  7. Up-regulation of inducible Gas1 contributed to the apoptosis of reactive astrocytes in injured substantia nigra.

  8. The C/EBP target Gas1 is induced in granulosa cells and is associated with ovulation and luteinization.

  9. the overexpression of Gas1 (growth arrest specific 1) gene reduces the size, proliferating activity and malignancy of liver tumors.

  10. WT1 modulates receptor tyrosine kinase signaling in nephron progenitor cell by directing the expression of Gas1.

  11. When Shh is presented as a point source, enteric axons turn away from it in a Gas1-dependent manner.

  12. We demonstrated that tGas1 has an antineoplastic effect, and the results support the potential of tGas1 as an adjuvant for the treatment of gliomas

  13. widespread distribution and cellular localization of the GAS1 native protein in adult mammalian CNS

  14. finding that Gas1 is transcribed at the G(1)/S transition suggests that the gene may exert a novel function during cell proliferation.

  15. Gas1 promotes myogenic differentiation through regulation of cell cycle arrest and is critical to activate p38MAPK

  16. Genetic loss-of-function of GAS1, CDO, and BOC in SHH is associated with defective neural patterning.

  17. Gas1 acts to maintain high levels of FGF10 at the tip mesenchyme and support the proposal that Fgf10 expression in this region is crucial for maintaining Fgf8 expression in the AER

  18. Gas1 is related to the GDNF alpha receptors and regulates Ret signaling

  19. GAS1 acts cooperatively with Patched1 for Hedgehog binding and enhances signaling activity in a cell-autonomous manner.

  20. Gas1 and Cdo cooperate to promote Shh signaling during neural tube patterning, craniofacial, and vertebral development

GAS1 Antigen Profile

Protein Summary

Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.

Gene names and symbols associated with GAS1

  • growth arrest specific 1 (GAS1) antibody
  • growth arrest specific 1 (Gas1) antibody
  • growth arrest specific 1 (gas1) antibody
  • growth arrest-specific 1 (GAS1) antibody
  • growth arrest-specific 1 (Gas1) antibody
  • growth arrest-specific 1b (gas1b) antibody
  • AW554192 antibody
  • Gas-1 antibody
  • im:7428747 antibody
  • MGC147541 antibody
  • wu:fc54h12 antibody
  • zgc:153938 antibody

Protein level used designations for GAS1

GAS-1 , Growth arrest-specific gene-1 , growth arrest-specific protein 1 , growth arrest-specific 1 , growth arrest-specific protein 1-like , growth arrest-specific 1b

2619 Homo sapiens
14451 Mus musculus
540336 Bos taurus
607496 Canis lupus familiaris
736324 Pan troglodytes
780149 Xenopus (Silurana) tropicalis
770168 Gallus gallus
683470 Rattus norvegicus
777760 Danio rerio
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