anti-Growth Differentiation Factor 15 (GDF15) Antibodies

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Additionally we are shipping GDF15 Kits (90) and GDF15 Proteins (37) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GDF15 9518 Q99988
GDF15 23886 Q9Z0J7
GDF15 29455 Q9Z0J6
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Top anti-GDF15 Antibodies at antibodies-online.com

Showing 10 out of 334 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: GDF-15 Antibody [NBP1-81050] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. Western Blot: GDF-15 Antibody [NBP1-81050] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GDF15 Antibody Titration:  0.2-1 ug/ml  Positive Control:  PANC1 cell lysate GDF15 is strongly supported by BioGPS gene expression data to be expressed in Human PANC1 cells WB Suggested Anti-GDF15 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: PANC1 cell lysate <br /> GDF15 is strongly supported by BioGPS gene expression data to be expressed in Human PANC1 cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit HRP ELISA, WB Western blot using affinity purified anti-NAG-1/GDF15 (C-terminal) antibody shows detection NAG-1 purified from CHO cells as a 14 kDa band corresponding to monomer and a 28 kDa band corresponding to dimerized NAG-1. Samples were electro-phoresed on a 4-20% gradient gel under reducing conditions. Lane 1 shows NAG-1 detection. Lane 2 shows reactivity is blocked when this antibody is pre-incubated with the immunizing peptide prior to Western blotting. 100 μg Log in to see 7 to 9 Days
$389.00
Details
Human Rabbit Biotin ELISA, WB Western blot using affinity purified anti-NAG-1/GDF15 (C-terminal) antibody shows detection NAG-1 purified from CHO cells as a 14 kDa band corresponding to monomer and a 28 kDa band corresponding to dimerized NAG-1. Samples were electro-phoresed on a 4-20% gradient gel under reducing conditions. Lane 1 shows NAG-1 detection. Lane 2 shows reactivity is blocked when this antibody is pre-incubated with the immunizing peptide prior to Western blotting. 100 μg Log in to see 7 to 9 Days
$389.00
Details
Mouse Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-NAG-1/GDF15 (C-terminal) antibody shows detection NAG-1 purified from CHO cells as a 14 kDa band corresponding to monomer and a 28 kDa band corresponding to dimerized NAG-1. Samples were electro-phoresed on a 4-20% gradient gel under reducing conditions. Lane 1 shows NAG-1 detection. Lane 2 shows reactivity is blocked when this antibody is pre-incubated with the immunizing peptide prior to Western blotting. 100 μg Log in to see 7 to 9 Days
$389.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185465 (0.1µg/ml) staining of Human Prostate lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated WB Western blot analysis of GDF15 expression in HepG2 (A), NIH3T3 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit HRP ELISA, WB In this sandwich ELISA, NAG-1 was captured from human serum using the following antibodies (see Related Products below): anti-NAG-1/GDF15 (C terminal specific), anti-NAG-1/GDF15 (N terminal specific (PAN)), anti-NAG-1/GDF15 (H-variant) and anti-NAG-1/GDF15 (D-variant) polyclonal antibodies. Micro titer plates were coated with capture antibody at 1 µg/mL. Control plates received PBS only (data not shown). After overnight incubation and blocking, independent experiments using 20 random normal human sera were performed. Neat normal sera were applied and incubated for 1 h at 37 °C. After washing, HRP conjugated anti-NAG-1/GDF15 (C terminal specific) antibody was added for detection at 100 µL per well at 1 µg/mL. Following further incubation for 1 hr at 37°C, the plates were washed and TMBE was added as an HRP substrate for 30 min. The reaction was stopped by 1 M H2SO4 and values were measured at 450nm. 100 μg Log in to see 7 to 9 Days
$389.00
Details
Human Rabbit Biotin ELISA, WB In this sandwich ELISA, NAG-1 was captured from human serum using the following antibodies (see Related Products below): anti-NAG-1/GDF15 (C terminal specific), anti-NAG-1/GDF15 (N terminal specific (PAN)), anti-NAG-1/GDF15 (H-variant) and anti-NAG-1/GDF15 (D-variant) polyclonal antibodies. Micro titer plates were coated with capture antibody at 1 µg/mL. Control plates received PBS only (data not shown). After overnight incubation and blocking, independent experiments using 20 random normal human sera were performed. Neat normal sera were applied and incubated for 1 h at 37 °C. After washing, HRP conjugated anti-NAG-1/GDF15 (C terminal specific) antibody was added for detection at 100 µL per well at 1 µg/mL. Following further incubation for 1 hr at 37°C, the plates were washed and TMBE was added as an HRP substrate for 30 min. The reaction was stopped by 1 M H2SO4 and values were measured at 450nm. 100 μg Log in to see 7 to 9 Days
$389.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of GDF15 using anti- GDF15 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: 22RV whole Cell lysates,   Lane 2: human placenta tissue lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- GDF15 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for GDF15 at approximately 34KD. The expected band size for GDF15 is at 34KD. 100 μg Log in to see 4 to 6 Days
$240.00
Details

GDF15 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GDF15 Antibodies

  1. Human Polyclonal GDF15 Primary Antibody for IHC, IHC (p) - ABIN4313803 : Tabrizi, Kalloger, Köbel, Cipollone, Roskelley, Mehl, Gilks: Primary ovarian mucinous carcinoma of intestinal type: significance of pattern of invasion and immunohistochemical expression profile in a series of 31 cases. in International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010 (PubMed)
    Show all 8 Pubmed References

  2. Mouse (Murine) Polyclonal GDF15 Primary Antibody for IHC - ABIN966198 : Iguchi, Chrysovergis, Lee, Baek, Langenbach, Eling: A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2. in Cancer letters 2009 (PubMed)
    Show all 7 Pubmed References

  3. Mouse (Murine) Polyclonal GDF15 Primary Antibody for IHC - ABIN966197 : Cekanova, Lee, Donnell, Sukhthankar, Eling, Fischer, Baek: Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice. in Cancer prevention research (Philadelphia, Pa.) 2009 (PubMed)
    Show all 7 Pubmed References

  4. Mouse (Murine) Polyclonal GDF15 Primary Antibody for IHC - ABIN966196 : Ding, Mracek, Gonzalez-Muniesa, Kos, Wilding, Trayhurn, Bing: Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. in Endocrinology 2009 (PubMed)
    Show all 7 Pubmed References

  5. Human Polyclonal GDF15 Primary Antibody for IF (p), IHC (p) - ABIN704561 : Ruan, Li, Nie, Zhou, Zou: Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer. in International journal of clinical and experimental medicine 2015 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal GDF15 Primary Antibody for ELISA, WB - ABIN269826 : Comitato, Nesaretnam, Leoni, Ambra, Canali, Bolli, Marino, Virgili: A novel mechanism of natural vitamin E tocotrienol activity: involvement of ERbeta signal transduction. in American journal of physiology. Endocrinology and metabolism 2009 (PubMed)
    Show all 2 Pubmed References

  7. Mouse (Murine) Polyclonal GDF15 Primary Antibody for ELISA, WB - ABIN1043801 : Baek, Eling: Changes in gene expression contribute to cancer prevention by COX inhibitors. in Progress in lipid research 2006 (PubMed)

More Antibodies against GDF15 Interaction Partners

Human Growth Differentiation Factor 15 (GDF15) interaction partners

  1. GDF-15 in blood is more accurate in differentiating pancreatic mass due to chronic pancreatitis from pancreatic adenocarcinoma than Ca19-9. the combination of GDF-15 with Ca125 (show MUC16 Antibodies) is remarkably useful in differentiating pancreatic mass.

  2. Our results show GDF-15 as an effective biomarker in patients with metastatic colorectal cancer

  3. GDF-15 and TRAIL-R2 (show TNFRSF10B Antibodies) were the most powerful Proximity Extension Assay chip biomarkers in predicting long-term all-cause mortality in patients with acute myocardial infarction.

  4. This study found that the mean serum GDF15 levels in the Parkinson Disease patients were significantly higher than those of the healthy control group. Secondly, in the Parkinson Disease patients, the GDF15 levels were significantly higher in the men than in the women.

  5. Elevated GDF-15 correlates with lack of reverse remodeling and increased mortality after TAVR and improves risk prediction of mortality.

  6. Initial serum GDF15 level showed an inverse correlation with serum glomerular filtration rate and was associated with worse renal outcome in immunoglobulin A nephropathy.

  7. data reveal that YAP (show YAP1 Antibodies) promotes metastasis of breast cancer cells by repressing GDF15 transcription and present a novel molecular mechanism underlying the pro-metastasis function of YAP (show YAP1 Antibodies) oncoprotein, with the implication of a therapeutic avenue for breast cancer treatment.

  8. GDF15 was significantly correlated with mitochondrial disease severity and the proportion of ragged (show SOX18 Antibodies)-red fibers identified in skeletal muscle.

  9. GDF-15 serum levels were elevated in patients with Systemic sclerosis and correlated with the extent of skin fibrosis, and it was found to be higher in Systemic sclerosis patients with interstitial pulmonary fibrosis

  10. Enhanced radiosensitivity and decreased migration in cells caused by CDP138 knockdown are partially dependent on GDF15 inhibition.

Mouse (Murine) Growth Differentiation Factor 15 (GDF15) interaction partners

  1. GDF15 is a myokine secreted by aging-related stress and may control aging phenotype

  2. Membrane-protein extraction and use of an intracellular protein (show CKAP2 Antibodies)-transport inhibitor showed that GDF-15 promoted CaV3.1 (show CACNA1G Antibodies) and CaV3.3 (show CACNA1I Antibodies) alpha-subunit (show POLG Antibodies) expression by trafficking to the membrane.

  3. CHOP (show DDIT3 Antibodies) activates Gdf15 transcription via binding to its promoter upon endoplasmic reticulum stress.

  4. The ANT1 (show SLC25A4 Antibodies)-deficient muscle mitochondria produce excess reactive oxygen species (ROS (show ROS1 Antibodies)) and are partially uncoupled. Hence, the muscle respiration under nonphosphorylating conditions is increased. Muscle transcriptome analysis revealed the induction of mitochondrial biogenesis, down-regulation of diabetes-related genes, and increased expression of the genes encoding the myokines FGF21 (show FGF21 Antibodies) and GDF15.

  5. isolating GFRAL as the receptor for GDF15-induced anorexia and weight loss, the identification of a mechanistic basis for the non-homeostatic regulation of neural circuitry by a peripheral signal associated with tissue damage and stress; findings provide opportunities to develop therapeutic agents for the treatment of disorders with altered energy demand

  6. These data suggest that GDF15 is required for IL-13 (show IL13 Antibodies)-induced improvement of glucose intolerance in mice fed an HFD.

  7. HIF-1alpha (show HIF1A Antibodies) and GDF15 expression are inversely related under normoxia and hyperoxia.

  8. This is the first study defining the role of Mic-1/Gdf15 in a number of behavioural domains.

  9. epithelial restitution was promoted by enhanced NAG-1 expression and subsequent enterocyte locomotion during the early wound-healing process

  10. both GDF-15 and TGF-beta1 (show TGFB1 Antibodies) counteract chemokine (show CCL1 Antibodies)-induced integrin activation on neutrophils via the ALK-5 (show TGFBR1 Antibodies)/TGF-betaRII heterodimer.

GDF15 Antigen Profile

Protein Summary

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Gene names and symbols associated with GDF15

  • growth differentiation factor 15 (GDF15) antibody
  • growth differentiation factor 15 (Gdf15) antibody
  • GDF-15 antibody
  • GDF15 antibody
  • MIC-1 antibody
  • MIC1 antibody
  • NAG-1 antibody
  • PDF antibody
  • PLAB antibody
  • PTGFB antibody
  • SBF antibody

Protein level used designations for GDF15

growth differentiation factor 15 , NRG-1 , NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 , NSAID-activated gene 1 protein , NSAID-regulated gene 1 protein , PTGF-beta , growth/differentiation factor 15 , macrophage inhibitory cytokine 1 , placental TGF-beta , placental bone morphogenetic protein , prostate differentiation factor , GDF-15 , macrophage inhibiting cytokine-1

GENE ID SPECIES
719466 Macaca mulatta
9518 Homo sapiens
23886 Mus musculus
29455 Rattus norvegicus
468770 Pan troglodytes
100718010 Cavia porcellus
100379630 Sus scrofa
484822 Canis lupus familiaris
618677 Bos taurus
100913168 Ovis aries
Selected quality suppliers for anti-GDF15 (GDF15) Antibodies
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