Growth Differentiation Factor 15 (GDF15) ELISA Kits

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Additionally we are shipping GDF15 Antibodies (281) and GDF15 Proteins (38) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GDF15 9518 Q99988
GDF15 23886 Q9Z0J7
GDF15 29455 Q9Z0J6
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Top GDF15 ELISA Kits at

Showing 10 out of 51 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human < 2 pg/mL 2-800 pg/mL 96 Tests 2 to 3 Days
Mouse 10pg/mL 15.6-1000 pg/mL Mouse GDF-15 PicoKine ELISA Kit standard curve 96 Tests 4 to 6 Days
Rat 5.9 pg/mL 15.62 pg/mL - 1000 pg/mL 96 Tests 13 to 16 Days
Human 2.73 pg/mL 6.86 pg/mL - 5000 pg/mL Typical standard curve 96 Tests 13 to 16 Days
Mouse 1.27 pg/mL 2.74 pg/mL - 2000 pg/mL   96 Tests 13 to 16 Days
Rat 1.21 pg/mL 2.74 pg/mL - 2000 pg/mL   96 Tests 13 to 16 Days
Rabbit 9.375 pg/mL 15.625-1000 pg/mL Typical standard curve 96 Tests 12 to 14 Days
Pig 18.75 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests 12 to 14 Days
Guinea Pig 1.0 pg/mL 250-5000 pg/mL   96 Tests 15 to 18 Days
Chicken 18.75 pg/mL 31.25-2000 pg/mL   96 Tests 12 to 14 Days

Top referenced GDF15 ELISA Kits

  1. Human GDF15 ELISA Kit for Sandwich ELISA - ABIN624984 : Barderas, Mendes, Torres, Bartolomé, López-Lucendo, Villar-Vázquez, Peláez-García, Fuente, Bonilla, Casal: In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion. in Molecular & cellular proteomics : MCP 2013 (PubMed)
    Show all 11 Pubmed References

  2. Human GDF15 ELISA Kit for Sandwich ELISA - ABIN365728 : Jiang, Yu, Wang, Tang, Guo, Jiao: Regulation of hepcidin through GDF-15 in cancer-related anemia. in Clinica chimica acta; international journal of clinical chemistry 2014 (PubMed)

  3. Human GDF15 ELISA Kit for Sandwich ELISA - ABIN415137 : Sun, Huang, Phillips, Luo, Zhu, Shi, Li: Growth differentiation factor 15 and coronary collateral formation. in Clinical cardiology 2010 (PubMed)

More ELISA Kits for GDF15 Interaction Partners

Human Growth Differentiation Factor 15 (GDF15) interaction partners

  1. Data suggest that growth differentiation factor 15 (GDF-15) may precisely reflect the fibrotic degree in patients with immunoglobulin G4-related disease (IgG4-RD).

  2. GDF15 expression was increased in the livers of human subjects with nonalcoholic steatohepatitis.

  3. The relatively high GDF-15 bioavailability might partly explain the protective cardiovascular effects of metformin. GDF-15 is a biomarker in type 2 diabetes.

  4. Restoring the balance of testosterone and estradiol may inhibit the effects of GDF-15.

  5. There was null association between GDF15 levels and anthropometric outcomes. A consistent significant causal association was observed between GDF15 and estimated bone mineral density.

  6. GDF15 may serve as a negative feedback mechanism to control energy balance in nonalcoholic fatty liver disease.

  7. Study results revealed that GDF15 could inhibit the proliferation, migration and invasion, while promoting apoptosis of A549 cells. In addition, GDF15 significantly decreased the number and sites of lung metastases and bone metastases in mouse xenograft model compared to the control group. SMAD2 and phosphoSMAD2 protein expression was lower in the GDF15overexpressing A549 cells.

  8. this paper shows that increased GDF-15 expression levels are associated with unfavorable overall survival in patients with digestive system tumors

  9. GDF-15 may be useful for identification of people with a risk of incident diabetes, especially if those people are

  10. GDF15 could promote cell viability, invasion and migration of LoVo cells through EMT induction

  11. in prostate cancer, CtBP1-regulated miR-34a modulates STMN1 expression and is involved in cancer progression through the CtBP1\miR-34a\STMN1\GDF15 axis. The CtBP1\miR-34a\STMN1\GDF15 axis is a potential therapeutic target for treatment of aggressive prostate cancer

  12. The role of the GDF-15 protein in amyloid-beta clearance through the enhancement of amyloid-beta-degrading enzyme secretion from microglia.

  13. GDF-15 has prognostic implications for different outcomes in patients with AL and adds prognostic information independent of that provided by cardiac and renal risk biomarkers.

  14. Our data demonstrated that GDF15 promoted the proliferation of cervical cancer cells via the up-regulation of CyclinD1 and CyclinE1 and the down-regulation of p21 through both the PI3K/AKT and MAPK/ERK signaling pathways in a complex with ErbB2.

  15. Circulating GDF-15 is a biomarker of muscle loss in pulmonary arterial hypertension that is responsive to treatment

  16. GDF15 secreted by leukemic cells was involved in the morphological remodeling of marrow adipocytes, which can in turn promote leukemic cell growth, indicating that GDF15 may be a promising treatment target for AML patients.

  17. For urothelial carcinoma of the upper urinary tract and renal cell carcinoma, serum hepcidin levels as well as serum GDF-15 levels were increased compared to sera of controls. High serum hepcidin and GDF-15 levels were associated with metastases and cancer relapse. Also, in both entities, the overall survival was decreased in patients with increased serum hepcidin and GDF-15 levels.

  18. results support that upregulation of GDF-15 in the presence of low testosterone levels during coronary artery disease progression is a potential mechanism by which GDF-15 affects CAD.

  19. Studied iron metabolism in polycythemia vera and essential thrombocytosis using serum levels of hepcidin, GDF15, and mitoferrin-1.

  20. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

Mouse (Murine) Growth Differentiation Factor 15 (GDF15) interaction partners

  1. GDF15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice.

  2. GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury

  3. Circulating GDF-15 is a biomarker of muscle loss in pulmonary arterial hypertension that is responsive to treatment.

  4. Studied effect of recombinant mouse growth differentiation factor 15 (GDF15) on adiposity and metabolism of mice with high fat diet induced obesity.

  5. GDF15 plays a role in hematopoiesis

  6. ur results demonstrate a novel and critical role of hepatic GDF15 activated by IRE1alpha-XBP1s branch in regulating adaptive responses of liver upon starvation stress.

  7. GDF15 is a myokine secreted by aging-related stress and may control aging phenotype

  8. Membrane-protein extraction and use of an intracellular protein-transport inhibitor showed that GDF-15 promoted CaV3.1 and CaV3.3 alpha-subunit expression by trafficking to the membrane.

  9. CHOP activates Gdf15 transcription via binding to its promoter upon endoplasmic reticulum stress.

  10. The ANT1-deficient muscle mitochondria produce excess reactive oxygen species (ROS) and are partially uncoupled. Hence, the muscle respiration under nonphosphorylating conditions is increased. Muscle transcriptome analysis revealed the induction of mitochondrial biogenesis, down-regulation of diabetes-related genes, and increased expression of the genes encoding the myokines FGF21 and GDF15.

  11. isolating GFRAL as the receptor for GDF15-induced anorexia and weight loss, the identification of a mechanistic basis for the non-homeostatic regulation of neural circuitry by a peripheral signal associated with tissue damage and stress; findings provide opportunities to develop therapeutic agents for the treatment of disorders with altered energy demand

  12. These data suggest that GDF15 is required for IL-13-induced improvement of glucose intolerance in mice fed an HFD.

  13. HIF-1alpha and GDF15 expression are inversely related under normoxia and hyperoxia.

  14. This is the first study defining the role of Mic-1/Gdf15 in a number of behavioural domains.

  15. epithelial restitution was promoted by enhanced NAG-1 expression and subsequent enterocyte locomotion during the early wound-healing process

  16. both GDF-15 and TGF-beta1 counteract chemokine-induced integrin activation on neutrophils via the ALK-5/TGF-betaRII heterodimer.

  17. GDF15 is a potent mitohormetic signal that safeguards against the onset of obesity and insulin resistance.

  18. The aim of this study was to identify the role of endogenous Gdf-15 in the MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease (PD) by comparing Gdf-15 (+/+) and Gdf-15 (-/-) mice.

  19. The results of this study indicated the importance of Gdf-15 in promoting survival of DAergic neurons and regulating the inflammatory response post 6-OHDA lesion.

  20. endogenous Growth/differentiation factor-15 is beneficial for axon regeneration following sciatic nerve crush

GDF15 Antigen Profile

Antigen Summary

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Gene names and symbols associated with GDF15

  • growth differentiation factor 15 (GDF15) antibody
  • growth differentiation factor 15 (Gdf15) antibody
  • GDF-15 antibody
  • GDF15 antibody
  • MIC-1 antibody
  • MIC1 antibody
  • NAG-1 antibody
  • PDF antibody
  • PLAB antibody
  • PTGFB antibody
  • SBF antibody

Protein level used designations for GDF15

growth differentiation factor 15 , NRG-1 , NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 , NSAID-activated gene 1 protein , NSAID-regulated gene 1 protein , PTGF-beta , growth/differentiation factor 15 , macrophage inhibitory cytokine 1 , placental TGF-beta , placental bone morphogenetic protein , prostate differentiation factor , GDF-15 , macrophage inhibiting cytokine-1

719466 Macaca mulatta
9518 Homo sapiens
23886 Mus musculus
29455 Rattus norvegicus
468770 Pan troglodytes
100718010 Cavia porcellus
100379630 Sus scrofa
484822 Canis lupus familiaris
618677 Bos taurus
100913168 Ovis aries
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