anti-Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) Antibodies

guanylyl cyclase\; functions as receptor for heat-stable enterotoxin responsible for acute diarrhea [RGD, Feb 2006].. Additionally we are shipping GUCY2C Kits (12) and GUCY2C Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GUCY2C 2984 P25092
GUCY2C 14917 Q3UWA6
GUCY2C 25711 P23897
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Top anti-GUCY2C Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) . Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: GUCY2C Antibody [NBP1-81788] - Staining of human lateral ventricle shows strong cytoplasmic positivity in neuronal cells. Immunohistochemistry-Paraffin: GUCY2C Antibody - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Mouse Un-conjugated WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) . Dilution: 1:500~1000 50 μg Log in to see 8 to 11 Days
$461.00
Details
Human Mouse Un-conjugated ELISA, WB GUCY2C monoclonal antibody (M04A), clone 2H8 Western Blot analysis of GUCY2C expression in U-2 OS . Western Blot detection against Immunogen (37.73 KDa) . 200 μL Log in to see 11 to 12 Days
$354.20
Details
Chicken Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.1 KDa) . 50 μL Log in to see 11 to 12 Days
$231.53
Details
Mouse Rabbit Un-conjugated WB   100 μL Log in to see 16 Days
$334.77
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using GUCY2C antibody (ABIN5997862) at 1/1000 dilution. 100 μL Log in to see 11 to 18 Days
$412.19
Details
Human Rabbit Un-conjugated WB   0.1 mL Log in to see 6 to 8 Days
$588.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 11 to 16 Days
$881.57
Details

Top referenced anti-GUCY2C Antibodies

  1. Human Polyclonal GUCY2C Primary Antibody for IHC, IHC (p) - ABIN4316480 : Brenna, Bruland, Furnes, Granlund, Drozdov, Emgård, Brønstad, Kidd, Sandvik, Gustafsson: The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease. in Scandinavian journal of gastroenterology 2015 (PubMed)

More Antibodies against GUCY2C Interaction Partners

Human Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) interaction partners

  1. High Expressions of guanylyl cyclase C is associated with rectal cancer.

  2. The findings support that the activating mutation in GUCY2C creates an intestinal environment with a major influence on the microbiota, which could contribute to the increased susceptibility to inflammatory bowel disease in patients with Familial GUCY2C diarrhea syndrome.

  3. Results demonstrate that GC-C and its ligands, guanylin (show GUCA2A Antibodies) and uroguanylin (show GUCA2B Antibodies) are downregulated in ulcerative colitis (UC), and this downregulation is more significant with aggravation of the clinical condition. Therefore, the GC-C signaling pathway may be implicated in the progression of UC.

  4. the expression of GCC is maintained throughout the process of tumor progression and formation of metastatic disease.

  5. To investigate gut (show GUSB Antibodies) motility and hormones before and after a meal in Familial GUCY2C diarrhea syndrome patients and compare with healthy controls

  6. Mutations in GUCY2C indicate a role for this receptor in the pathogenesis of sporadic Congenital secretory diarrhea.

  7. these data support Ad5 (show PSEN2 Antibodies)-GUCY2C-PADRE as a safe and effective vaccination strategy in preclinical models and position Ad5 (show PSEN2 Antibodies)-GUCY2C-PADRE for Phase I clinical testing in colorectal cancer patients.

  8. Familial GUCY2C diarrhoea syndrome is caused by an activating mutation in the GUCY2C gene, which causes impaired contractility and fluid stagnation in the small bowel

  9. Findings show how caloric suppression of the guanylin (show GUCA2A Antibodies)-GUCY2C signaling axis links obesity to negation of a universal tumor suppressor pathway in colorectal cancer.

  10. Data show that individuals affected with meconium ileus (MI) had either homozygous or compound heterozygous variants in enterotoxin receptor GUCY2C.

Mouse (Murine) Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) interaction partners

  1. Loss of Gucy2c expression is associated with Acute Radiation-Induced GI Syndrome.

  2. Findings show how caloric suppression of the guanylin (show GUCA2A Antibodies)-GUCY2C signaling axis links obesity to negation of a universal tumor suppressor pathway in colorectal cancer.

  3. The GC-C signaling pathway blunts colonic mucosal inflammation that is initiated by systemic cytokine burst or loss of mucosal immune cell immunosuppression.

  4. GC-C signaling is an essential component of host defense during murine enteric infection by reducing bacterial load and preventing systemic dissemination of attaching/effacing-lesion forming bacterial pathogens such as C. rodentium.

  5. Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21 (show D4S234E Antibodies).

  6. guanylate cyclase-C

  7. GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT (show AKT1 Antibodies)-dependent intestinal barrier integrity

  8. The role for GUCY2C-directed CD8 (show CD8A Antibodies)(+) T cells targeting specific epitopes in antitumor efficacy.

  9. Data show that silencing of GUCY2C in mice disrupts satiation, resulting in hyperphagia and subsequent obesity and metabolic syndrome.

  10. a novel role for GC-C signaling in facilitating mucosal wounding and inflammation, and further suggest that this may be mediated, in part, through control of RELMbeta (show RETNLB Antibodies) production

GUCY2C Antigen Profile

Protein Summary

guanylyl cyclase\; functions as receptor for heat-stable enterotoxin responsible for acute diarrhea

Gene names and symbols associated with GUCY2C

  • guanylate cyclase 2C (GUCY2C) antibody
  • guanylate cyclase 2c (Gucy2c) antibody
  • guanylate cyclase 2C (Gucy2c) antibody
  • guanylate cyclase 2C L homeolog (gucy2c.L) antibody
  • guanylate cyclase 2C (gucy2c) antibody
  • AI893437 antibody
  • DIAR6 antibody
  • GC-C antibody
  • GCC antibody
  • GUC2C antibody
  • Gucy2c antibody
  • gucy2c-A antibody
  • MECIL antibody
  • MUCIL antibody
  • STAR antibody

Protein level used designations for GUCY2C

GC-C , STA receptor , guanylyl cyclase C , hSTAR , heat-stable enterotoxin receptor , intestinal guanylate cyclase , heat stable enterotoxin receptor , Guanylate cyclase 2C (heat stable enterotoxin receptor) , guanylate cyclase 2C , guanylate cyclase 2C (heat stable enterotoxin receptor) , heat-stable enterotoxin receptor-like

GENE ID SPECIES
2984 Homo sapiens
282244 Bos taurus
397193 Sus scrofa
14917 Mus musculus
25711 Rattus norvegicus
100135536 Cavia porcellus
378662 Xenopus laevis
417968 Gallus gallus
473375 Pan troglodytes
486671 Canis lupus familiaris
699191 Macaca mulatta
100406002 Callithrix jacchus
100460918 Pongo abelii
100563369 Anolis carolinensis
100594944 Nomascus leucogenys
100008740 Oryctolagus cuniculus
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