anti-HERV-FRD Provirus Ancestral Env Polyprotein Antibodies

Many different endogenous retrovirus families are expressed in normal placental tissue at high levels, suggesting that endogenous retroviruses are functionally important in reproduction.

Data Quality
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  • 6
Type
  • 45
    Primary
Target
  • 45
    HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
  • 1412
  • 1234
  • 1168
  • 928
Application
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  • 19
  • 13
  • 6
  • 3
Reactivity
  • 42
  • 5
  • 5
  • 1
Host
  • 45
Clonality
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Binding Specificity
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  • 10
  • 6
  • 3
  • 2
Conjugate
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  • 5
  • 5
  • 3
  • 2
Isotype
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  • 2
Format
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Pubmed
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100 μL
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100 μg
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Application ELISA, IP, WB
Order details Cat. No. ABIN5558497
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100 μg
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100 μL
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100 μL
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100 μL
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100 μL
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HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) Antigen Profile

Protein Summary

Many different endogenous retrovirus families are expressed in normal placental tissue at high levels, suggesting that endogenous retroviruses are functionally important in reproduction. This gene is part of a endogenous retrovirus provirus on rat chromosome 12 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Gene names and symbols associated with Herv-frd

  • endogenous retrovirus group FRD member 1, envelope (ERVFRD-1) antibody
  • endogenous retrovirus group FRD member 1, envelope (Ervfrd-1) antibody
  • envFRD antibody
  • ERVFRDE1 antibody
  • GLLL6191 antibody
  • Gm52 antibody
  • HERV-FRD antibody
  • HERV-W/FRD antibody
  • Syna antibody
  • UNQ6191 antibody

Protein level used designations for Herv-frd

HERV-FRD provirus ancestral Env polyprotein , HERV-FRD_6p24.1 provirus ancestral Env polyprotein , endogenous retrovirus group FRD member 1 , envelope polyprotein , syncytin 2 , envelope glycoprotein syncytin-A , syncytin a

GENE ID SPECIES
405754 Homo sapiens
288602 Rattus norvegicus