anti-HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1) Antibodies

Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Additionally we are shipping HSPA Binding Protein, Cytoplasmic Cochaperone 1 Proteins (8) and HSPA Binding Protein, Cytoplasmic Cochaperone 1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSPBP1 23640 Q9NZL4
HSPBP1 246146 Q6IMX7
HSPBP1 66245 Q99P31
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Top anti-HSPA Binding Protein, Cytoplasmic Cochaperone 1 Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: Hspbp1 Sample Type: Rat Spleen lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
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Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
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Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC201814 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-HSPBP1 antibody (ABIN2454980), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSPBP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HSPBP1. 0.1 mL 2 to 3 Days
$482.90
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Human Rabbit Un-conjugated EIA, IHC (p), WB   0.4 mL 4 to 8 Days
$522.50
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Human Mouse Un-conjugated FACS, IF, WB 100 μL 11 to 14 Days
$522.50
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Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
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Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-HSPBP1 mouse monoclonal antibody (ABIN2454941) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HSPBP1 (RC201814). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSPBP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HSPBP1. 0.1 mL 2 to 3 Days
$462.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis in Jurkat cell line lysates (35ug/lane). HSPBP1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
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Human Rabbit Un-conjugated IP, WB Immunoprecipitation of HSPBP1 transfected lysate using anti-HSPBP1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with HSPBP1 MaxPab mouse polyclonal antibody (B01) . Western Blot analysis of HSPBP1 expression in transfected 293T cell line by HSPBP1 MaxPab polyclonal antibody.Lane 1: HSPBP1 transfected lysate(39.3 KDa).Lane 2: Non-transfected lysate. 100 μL 11 to 12 Days
$425.71
Details

Top referenced anti-HSPA Binding Protein, Cytoplasmic Cochaperone 1 Antibodies

  1. Human Polyclonal HSPBP1 Primary Antibody for WB - ABIN538025 : Alberti, Böhse, Arndt, Schmitz, Höhfeld: The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator. in Molecular biology of the cell 2004 (PubMed)
    Show all 2 Pubmed References

  2. Chicken Monoclonal HSPBP1 Primary Antibody for ICC, IF - ABIN266945 : Barker, Benovic: G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. in Biochemistry 2011 (PubMed)

  3. Human Monoclonal HSPBP1 Primary Antibody for FACS, IHC - ABIN2723123 : Tuo, Shu, She, Yang, Zou, Huang, Hu, Hu, Ren, Peng, Yang: Sorcin induces gastric cancer cell migration and invasion contributing to STAT3 activation. in Oncotarget 2017 (PubMed)

More Antibodies against HSPA Binding Protein, Cytoplasmic Cochaperone 1 Interaction Partners

Human HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1) interaction partners

  1. Circulating HspBp1 is associated with progression of HIV infection and can be used as a new marker to predict the prognosis and management of HIV infection

  2. Findings indicate a critical role of HspBP1 in differential CHIP/Hsp70 activities in neuronal and glial cells and the greater neuronal vulnerability to misfolded proteins in neurodegenerative diseases.

  3. downregulation of Hsp70 and HspBP1 represents a unique feature of patients with preterm prelabor rupture of membranes

  4. our results clearly show that HspBP1 acts as an endogenous negative regulator of HIV-1 gene-expression and replication by suppressing NF-kappaB-mediated activation of viral transcription.

  5. Oxidative stress, inducing formation of disulfide bond, can affect stability and conformational mobility of human HspB1.

  6. BAG-1M and HspBP1 had differential impacts on the dynamic composition of steroid receptor folding complexes

  7. shown that HspBP1 binds Tag7 in the conditioned medium of tumor CSML0 cells, thereby preventing formation of the cytotoxic Tag7-Hsp70 complex

  8. High gene expression of HspBP1 is associated with leukemia.

  9. Results report cooperative interactions involving Hsp70, Hsp40, and TPR1 that enhance Hsp70-dependent folding of chemically denatured substrates.

  10. Detection of hsp70 may be used as the screening marker for diagnosis of polycyclic aromatic hydrocarbons (PAHs)-related lung cancer related lung cancer, and may supplement the diagnostic value of conventional cytology.

  11. HspBP1 interferes with the CHIP-induced degradation of immature forms of the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates CFTR maturation.

  12. BAG2 binds to the carboxyl terminus of Hsp70-interacting protein (CHIP) and provides a cochaperone-dependent regulatory mechanism for preventing unregulated ubiquitylation of misfolded proteins by CHIP

  13. The results demonstrate that Hsp70 and HspBP1 are not coordinately regulated but provide evidence that an increase in the ratio of HspBP1 to Hsp70 correlates with apoptosis, in a similar way to reducing the amount of Hsp70.

  14. Stress-induced heat shock protein 70 (Hsp70) effectively protects cells against ultraviol ray-induced apoptosis in melanocytes bu penetrating mitchondrial and lysosomal membranes.

  15. Here, we report that upon the formation of huntingtin aggregates; endogenous cytosolic huntingtin, Hsc70/Hsp70 (heat shock protein and cognate protein of 70kDa) and syntaxin 1A become aggregate-centered.

  16. that HspBP1, by antagonizing the prosurvival activity of Hsp70, sensitizes tumor cells to cathepsin-mediated cell death.

  17. Association between endogenous LAP2alpha and Hsp70 in non-transfected cells was confirmed by co-immunoprecipitation.

  18. The two chaperones, HSP72 and HSPBP1, interact both physically and functionally, leading to the activation of th EGFR-ERK1/2 signalling pathway.

  19. Results indicate that low HspBP1 expression could be a marker of tumor aggressiveness.

  20. Our data suggest that HIP may prevent inclusion formation by facilitating the constitutive HSC70 refolding cycle and possibly by preventing aggregation.

Mouse (Murine) HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1) interaction partners

  1. Male HSPBP1knockout mice are sterile because of impaired meiosis and massive apoptosis of spermatocytes.

  2. Provides a critical cardioprotective effect in the setting of ischemia-reperfusion injury due in part to increased apoptosis in cardiac cells.

HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1) Antigen Profile

Protein Summary

Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.

Gene names and symbols associated with HSPBP1

  • HSPA (Hsp70) binding protein 1 (HSPBP1) antibody
  • HSPA (Hsp70) binding protein 1 (Hspbp1) antibody
  • HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 (Hspbp1) antibody
  • 1500019G21Rik antibody
  • FES1 antibody

Protein level used designations for HSPBP1

Hsp70 binding protein 1 , heat shock protein-binding protein 1 , hsp70 interacting protein , hsp70-binding protein 1 , hsp70-binding protein 2 , hsp70-interacting protein 1 , hsp70-interacting protein 2 , hspBP2 , HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 , SPA ) binding protein, cytoplasmic cochaperone 1

GENE ID SPECIES
23640 Homo sapiens
246146 Rattus norvegicus
66245 Mus musculus
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