HSPBP1 antibody (AA 51-150)

Catalog No. ABIN6989222

The Rabbit Polyclonal anti-HSPBP1 antibody is suitable to detect HSPBP1 in samples from Human. It has been validated for IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for HSPBP1 antibody (AA 51-150) (ABIN6989222)

Target: HSPBP1 (HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPBP1 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-HSPBP1 Antibody

Binding Specificity: AA 51-150

Purpose: HspBP1 Polyclonal Antibody

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HspBP1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HSPBP1

Target: HSPBP1 (HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))

Alternative Name: HspBP1

Background:

Synonyms: 1500019G21Rik, FES1, Heat shock protein 70 binding protein, Heat shock protein 70 interacting protein, Heat shock protein binding protein 1, Heat shock protein-binding protein 1, Heat-shock 70-KD protein-binding protein 1, HPBP1_HUMAN, Hsp 70 binding protein, Hsp 70 interacting protein, Hsp70 binding protein 1, Hsp70 binding protein 2, Hsp70 interacting protein 1, Hsp70 interacting protein 2, Hsp70-binding protein 1, Hsp70-binding protein 2, Hsp70-interacting protein 1, Hsp70-interacting protein 2, HSPA (heat shock 70 kDa) binding protein, cytoplasmic cochaperone 1, HSPA-binding protein 1, HSPBP, HspBP1, HspBP2, PP1845.

Background: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.

Gene ID: 23640

UniProt: Q9NZL4