anti-Hairy and Enhancer of Split 7 (Drosophila) (HES7) Antibodies

HES7 encodes a member of the hairy and enhancer of split family of bHLH transcription factors. Additionally we are shipping HES7 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HES7 84667 Q9BYE0
HES7 84653 Q8BKT2
HES7 287423  
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Top anti-HES7 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Rabbit Anti-HES7 Antibody Catalog Number: ARP30035 Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X Rabbit Anti-HES7 Antibody Catalog Number: ARP30035 Paraffin Embedded Tissue: Human Pancreas Cellular Data: Epithelial cells of pancreatic acinus Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  Hes7  Sample Type:  Mouse Stomach lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Hes7 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: NIH/3T3 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA   100 μg 6 to 7 Days
$291.53
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HES7 Antibody (N-term) in mouse heart tissue lysates (35ug/lane). HES7 (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$581.17
Details
Monkey Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of HES7 Antibody in mouse heart tissue lysates (35ug/lane) 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg 2 to 3 Days
$446.88
Details

More Antibodies against HES7 Interaction Partners

Human Hairy and Enhancer of Split 7 (Drosophila) (HES7) interaction partners

  1. an Indian family links Coats plus syndrome and dextrocardia with a homozygous novel CTC1 and a rare HES7 variation

  2. mutation of HES7 is uniquely associated with defects in vertebral, heart and neural tube formation, and this observation will help provide a discriminatory diagnostic guide in patients with SCD, as well as inform molecular genetic testing.

  3. MESP2, HES7 and DUSP6 genes may not be involved in the etiopathogenesis of sporadic and non-syndromic CS in Chinese Han population.

  4. Two new missense mutations in HES7 in a family with spondylocostal dysostosis.

  5. R25W missense mutation of HES7 is causative of Spondylocostal dysostosis.

Mouse (Murine) Hairy and Enhancer of Split 7 (Drosophila) (HES7) interaction partners

  1. Hes7 expression in the presomitic mesoderm was up-regulated through the E-box, T-box, and RBPj-binding element in the Hes7 essential region, presumably through synergistic signaling involving mesogenin1, T-box6 (Tbx6), and Notch1.

  2. Hes7 oscillation is synchronized between neighboring cells, and the posterior-anterior axis is self-organized as the central-peripheral axis

  3. Lengthening the third Hes7 intron by 10 or 20 kb disrupts accurate RNA splicing and inactivates the gene.

  4. Fgf signaling was found to be a primary target for hypoxia, which causes phenotypic variations of heterozygous mutations in Hes7 or Mesp2, suggesting gene-environment interaction through this signaling.

  5. Hes7 is a key regulator of the pace of the segmentation clock.

  6. Tbx6 and the Wnt pathway cooperatively regulate proper Hes7 expression.

  7. introns lead to an approximately 19-min delay in the Hes7 gene expression, and mathematical modeling suggested that without such a delay, Hes7 oscillations would be abolished

  8. there are differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis

  9. periodic repression by Hes7 protein is critical for the cyclic transcription of Hes7 and Lfng, and this negative feedback represents a molecular basis for the segmentation clock

  10. instability of Hes7 is essential for sustained oscillation and for its function as a segmentation clock

  11. Lunatic fringe and Hes7 controls their oscillatory expression during somitogenesis by forming negative feedback loop

  12. Hes7 oscillation is initiated by Fgf signaling and propagated/maintained anteriorly by Notch signaling.

  13. repressor functionality and the half-life of the protein is crucial for oscillatory expression of Hes7 and regular somite formation

  14. These results indicate that common amino acid residues are involved in both the transcriptional repressor activity and the instability of Hes7 protein, suggesting of a critical link between the transcription and degradation control.

  15. Sprouty4 does not oscillate in Hes7-null mutant mouse embryos, and Hes7 can inhibit FGF-induced transcriptional activity of the Sprouty4 promoter.

HES7 Antigen Profile

Protein Summary

This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HES7

  • hes family bHLH transcription factor 7 (HES7) antibody
  • hairy and enhancer of split 7 (Drosophila) (Hes7) antibody
  • hes family bHLH transcription factor 7 (Hes7) antibody
  • bHLHb37 antibody
  • SCDO4 antibody

Protein level used designations for HES7

bHLH factor Hes7 , class B basic helix-loop-helix protein 37 , hHes7 , transcription factor HES-7 , mHes7

GENE ID SPECIES
84667 Homo sapiens
612802 Canis lupus familiaris
617638 Bos taurus
84653 Mus musculus
287423 Rattus norvegicus
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