anti-Heat Shock 70kDa Protein 8 (HSPA8) Antibodies

HSPA8 encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members.

list all antibodies Gene Name GeneID UniProt
Anti-Human HSPA8 HSPA8 3312 P11142
Anti-Rat HSPA8 HSPA8 24468 P63018
Anti-Mouse HSPA8 HSPA8 15481 P63017
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-HSPA8 Antibodies at antibodies-online.com

Showing 10 out of 340 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HSPA8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate <b>Sample type:</b> rat brain lysate<br><b>Primary Dilution: </b>1:1000<br><b>Image Submitted By:</b> Jennifer Morgan, PhD &, David Busch<br>University of Texas in Austin 100 μL Log in to see 2 to 3 Days
$289.00
Details
Goat Rabbit Un-conjugated IHC, WB WB Suggested Anti-HSPA8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  COLO205 cell lysate <b>Sample Type:</b> 1. Lamprey CNS (20ug)<br>2. Rat Brain Lysate (20ug) <br><b>Primary Dilution: </b>1:1000<br><b>Secondary Antibody: </b>Goat anti-Rabbit HRP<br><b>Secondary Dilution:</b> 1:4000<br><b>Image Submitted by: </b>Jennifer Morgan, PhD &, David Busch<br>University of Texas in Austin 100 μL Log in to see 2 to 3 Days
$289.00
Details
Hamster Rabbit Un-conjugated BI, ICC, IF, IP, IHC, WB Hsc70 human Cell line mix 10ug 1 in 1000 Western Blotting. 100 μL Log in to see 2 to 3 Days
$350.90
Details
Human Mouse Un-conjugated AA, Bind, ELISA, ICC, IF, IHC, IP, PLA, WB Hsc70 (1F2 H5) human cell line mix copy. 50 μg Log in to see 2 to 3 Days
$220.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185659 (2µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:5000 IHC-P Image HSC70 antibody detects HSC70 protein at nucleolus on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. HSC70 antibody , dilution: 1:500. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Hamster Rabbit HRP BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Log in to see 2 to 3 Days
$389.40
Details
Hamster Rabbit FITC BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Log in to see 2 to 3 Days
$393.80
Details
Hamster Rabbit Alkaline Phosphatase (AP) BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Log in to see 2 to 3 Days
$396.00
Details
Hamster Rabbit Biotin BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Log in to see 2 to 3 Days
$398.20
Details

Top referenced anti-HSPA8 Antibodies

  1. Hamster Polyclonal HSPA8 Primary Antibody for BI, ICC - ABIN361819 : Boorstein, Ziegelhoffer, Craig: Molecular evolution of the HSP70 multigene family. in Journal of molecular evolution 1994 (PubMed)
    Show all 13 Pubmed References

  2. Human Monoclonal HSPA8 Primary Antibody for AA, Bind - ABIN361800 : Bork, Sander, Valencia: An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 10 Pubmed References

  3. Human Polyclonal HSPA8 Primary Antibody for FACS, IF - ABIN1944844 : Tsukahara, Yoshioka, Muraki: Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70. in Molecular pharmacology 2000 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal HSPA8 Primary Antibody for ELISA, WB - ABIN188549 : Zhang, Fan, Becker, Graff, Lee, Francomano: Comparison of gene expression profile between human chondrons and chondrocytes: a cDNA microarray study. in Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2006 (PubMed)

  5. Human Polyclonal HSPA8 Primary Antibody for IF (p), IHC (p) - ABIN709931 : Almiñana, Corbin, Tsikis, Alcântara-Neto, Labas, Reynaud, Galio, Uzbekov, Garanina, Druart, Mermillod: Oviduct extracellular vesicles protein content and their role during oviduct-embryo cross-talk. in Reproduction (Cambridge, England) 2017 (PubMed)

  6. Fish Polyclonal HSPA8 Primary Antibody for WB - ABIN361860 : Brown, Hong-Brown, Doxsey, Welch: Molecular chaperones and the centrosome. A role for HSP 73 in centrosomal repair following heat shock treatment. in The Journal of biological chemistry 1996 (PubMed)
    Show all 6 Pubmed References

More Antibodies against HSPA8 Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. hsp72 (show HSPA1A Antibodies) was more potent than hsc73 in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. These results demonstrate not only an important mechanism of Hsc70 in facilitating EV-A71 replication, but also a target for antiviral drug development.

  2. Post-transcriptional inhibition of HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of amyotrophic lateral sclerosis.

  3. Taken together, these data suggest hat (show MGEA5 Antibodies) the altered hydrogen bonding observed in the Hsc70 C17W mutant (where the connectivity between Mg2 (show MUC7 Antibodies)+.nucleotide and E175 is also disrupted) could bring about changes to Hsc70 domain communication, affecting peptide association while also limiting ATP hydrolysis.

  4. The roles of the E3 ubiquitin ligase (show MUL1 Antibodies), carboxy-terminus Hsc70 interacting protein (show ST13 Antibodies) (CHIP) in various types of cancers.

  5. Hsc70/Hsp90 (show HSP90 Antibodies) chaperones contribute to the conformational and functional maintenance of DeltaF508-CFTR (show CFTR Antibodies) at 37 degrees C.

  6. Engagement of the oligomer by LAP1 (show ANPEP Antibodies) triggers ATP hydrolysis and rapid complex disassembly. Thus the Torsin complex is a highly dynamic assembly whose oligomeric state is tightly controlled by distinctively localized cellular cofactors.

  7. Downregulation of Hsc70, Hsp70 (show HSP70 Antibodies), and IL-15 (show IL15 Antibodies) expression at gene and/or protein levels might support the retention of fertilization products in cases of missed abortion and blighted ovum.

  8. STRO-1 binds to immune-precipitated HSC70 and siRNA-mediated knock down of HSPA8 reduced STRO-1 binding.

  9. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  10. study demonstrates a critical role of Hsc70 in SV40 endoplasmic reticulum-to-cytosol penetration and reveal how SGTA (show SGTA Antibodies) controls Hsc70 to impact this process

Cow (Bovine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Single-particle fluorescence imaging tracks the dynamics of Hsc70 and its clathrin substrate in real time.

  2. The interaction of the molecular chaperone (show HSP90AA1 Antibodies) Hsc70 (HSPA8) with recombinant PrP (show PRNP Antibodies) was investigated.

  3. Structure of clathrin coat with bound Hsc70 and auxilin (show DNAJC6 Antibodies).

  4. specific association between HSP73 and gentamicin may reduce the chaperone activity of HSP73 in vitro and/or in vivo

  5. report role of HSC70 in the regulation of NMT

  6. studied the process of disassembly by using cryo-electron microscopy to identify the initial binding site of Hsc70 on clathrin-C58J baskets at pH 6, under which conditions disassembly does not proceed further. Hsc70 interactions involve two sites

  7. Coats assembled from recombinant clathrin are good substrates for ATP- and auxilin (show DNAJC6 Antibodies)-dependent, Hsc70-catalyzed uncoating.

  8. The structure of an Hsp110 (show HSPH1 Antibodies):Hsc70 nucleotide exchange complex, is reported.

  9. analysis of the formation of a stable complex between chaperonin-containing TCP-1 (show CCT6A Antibodies) (CCT (show TCP1 Antibodies)) and Hsc70

  10. Elevated expression of bovine heat shock cognate (hsc)70 protein increases diabetes and inflammation following islet beta cell damage in a transgenic mouse model.

Mouse (Murine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Post-transcriptional inhibition of HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of amyotrophic lateral sclerosis.

  2. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  3. Hsc70 interacts with FILIP (show FILIP1 Antibodies) to mediate its effects on non-muscle myosin IIb (show MYH10 Antibodies) and to regulate spine morphology

  4. HSPA1A (show HSPA1A Antibodies) and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  5. intracellular Salmonella recruit the host proteins LAMP-2A and Hsc73, key components of the host protein turnover pathway known as chaperone-mediated autophagy involved in transport of cytosolic proteins to the lysosome for degradation.

  6. these data demonstrate a novel interaction between Hsc70 and TH that regulates the activity and localization of the enzyme to synaptic vesicles, suggesting an important role for Hsc70 in dopamine homeostasis.

  7. C terminus of the hsc-70 LID domain as the structural interface interacting with endosomal Phosphatidylserine

  8. the association of MNSFbeta (show FAU Antibodies) with HSPA8 may promote RANKL (show TNFSF11 Antibodies)-induced osteoclastogenesis.

  9. Hspa8 plays a vital role in genetic differences in responses to stress and ethanol and their interactions

  10. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

HSPA8 Antigen Profile

Protein Summary

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HSPA8

  • heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L) antibody
  • heat shock protein family A (Hsp70) member 8 (HSPA8) antibody
  • heat shock protein family A (Hsp70) member 8 (Hspa8) antibody
  • heat shock 70kDa protein 8 (HSPA8) antibody
  • heat shock protein 8 (Hspa8) antibody
  • heat shock protein 8 (hspa8) antibody
  • 2410008N15Rik antibody
  • HSC54 antibody
  • Hsc70 antibody
  • Hsc71 antibody
  • Hsc73 antibody
  • HSP71 antibody
  • Hsp73 antibody
  • Hspa10 antibody
  • LAP1 antibody
  • NIP71 antibody
  • wu:fb01g06 antibody
  • wu:fi48b06 antibody

Protein level used designations for HSPA8

LPS-associated protein 1 , N-myristoyltransferase inhibitor protein 71 , constitutive heat shock protein 70 , heat shock 70kd protein 10 , heat shock cognate 71 kDa protein , heat shock cognate protein 54 , lipopolysaccharide-associated protein 1 , Hsc70 ATPase , heat shock 70 kDa protein 8 , heat shock 70kd protein 10 (HSC71) , heat shock cognate 71 kD protein , Heat shock cognate protein 70 , heat shock 70kD protein 8 , heat shock protein 8 , heat shock protein A8 , heat shock cognate 70 , heat shock cognate 71 kDa protein-like protein , heat shock protein 70 cognate , heat shock cognate hsc73 , heat shock protein cognate 70 , heat shock 70kDa protein 8 , heat shock cognate 71-kd protein

GENE ID SPECIES
379319 Xenopus laevis
3312 Homo sapiens
281831 Bos taurus
24468 Rattus norvegicus
395853 Gallus gallus
479406 Canis lupus familiaris
100009679 Equus caballus
100172711 Pongo abelii
15481 Mus musculus
573376 Danio rerio
Did you look for something else?