anti-Homeobox A5 (HOXA5) Antibodies

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Additionally we are shipping HOXA5 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HOXA5 3202 P20719
HOXA5 15402 P09021
HOXA5 79241  
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Top anti-HOXA5 Antibodies at antibodies-online.com

Showing 10 out of 129 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HOXA5 Antibody Titration:  0.2-1 ug/ml  Positive Control:  721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB Anti-HOXA5 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Anti-HOXA5 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Goat Un-conjugated ELISA, WB ABIN1590003 (1 µg/mL) staining of Mouse Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
$291.53
Details
Pig Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Human Breast (formalin-fixed, paraffin-embedded) stained with HOXA5 antibody ABIN462218 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Kidney (formalin-fixed, paraffin-embedded) stained with HOXA5 antibody ABIN462218 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 100 μL Log in to see 11 to 14 Days
$727.83
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-HOXA5 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other for ... 100 μL Log in to see 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of HOXA5 antibody (C-term E211) (ABIN390648) in mouse kidney tissue lysates (35 µg/lane). HOXA5 (arrow) was detected using the purified polyclonal antibody. Flow cytometric analysis of 293 cells using HOXA5 Antibody (C-term E211)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see Available
$363.46
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of extracts from Jurkat cells, using HXA5 antibody.,The lane on the left is treated with the antigen-specific peptide. ABIN6275191 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details

Top referenced anti-HOXA5 Antibodies

  1. Cow (Bovine) Polyclonal HOXA5 Primary Antibody for IHC, WB - ABIN2777305 : Boucherat, Montaron, Bérubé-Simard, Aubin, Philippidou, Wellik, Dasen, Jeannotte: Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis. in American journal of physiology. Lung cellular and molecular physiology 2013 (PubMed)

  2. Human Monoclonal HOXA5 Primary Antibody for IF, ELISA - ABIN516607 : Schummer, Thorpe, Giraldez, Bergan, Tewari, Urban: Evaluating Serum Markers for Hormone Receptor-Negative Breast Cancer. in PLoS ONE 2015 (PubMed)

  3. Human Polyclonal HOXA5 Primary Antibody for ELISA - ABIN548018 : Okada, Jiang, Lemieux, Jeannotte, Su, Zhang: Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L. in Nature cell biology 2006 (PubMed)

  4. Pig (Porcine) Polyclonal HOXA5 Primary Antibody for ELISA, WB - ABIN4319692 : Yoo, Park, Kim, Jung, Chang: Epigenetic inactivation of HOXA5 and MSH2 gene in clear cell renal cell carcinoma. in Pathology international 2010 (PubMed)

More Antibodies against HOXA5 Interaction Partners

Human Homeobox A5 (HOXA5) interaction partners

  1. homeobox A5 and signal transducer and activator of transcription 3 were physically associated and appeared interdependent in activating PD-L1 transcription. Functional studies showed that HDAC8-mediated regulation of PD-L1 expression participated in modulating anti-melanoma T-cell responses.

  2. Study revealed that HOXA5 inhibits cervical cancer progression by regulating AKT/p27, proposing the potential role of HOXA5 in the prevention and treatment of cervical cancer.

  3. HOXA5 overexpression in U2OS and MG63 cells markedly reduced cell survival and proliferation and elevated cell apoptosis and caspase-3 activity.

  4. HOXA5 functions as a tumor suppressor in regulating tumor growth of gastric cancer (GC) under regulation of miR-196a, supporting its potential utility as a therapeutic target for GC.

  5. LncRNA GAS5 depressed OA development by targeting miR-196a-5p and thereby down-regulating HOXA5 expression, providing substance for developing lncRNA-based strategies to treat OA.

  6. Low HOXA5 expression is associated with Gastric cancer.

  7. Research demonstrated that depletion of HOXA5 inhibited osteogenic differentiation and repressed cell proliferation by arresting cell cycle progression at the S phase via p16(INK4A) , p18(INK4C) , and Cyclin A in SCAPs, indicating that HOXA5 has a significant role in maintaining the proliferation and differentiation potential of dental-tissue-derived MSCs.

  8. The study demonstrated that MPP8 was associated with non-small cell lung cancer cell proliferation through regulation of HOXA5.

  9. The present study demonstrates that HOXA5 can be silenced in the psoriatic stratum corneum due to DNA methylation of the CGI located in the 5' region of HOXA5.

  10. study implicates HOXA5 as a chromosome 7-associated gene-level locus that promotes selection for gain of whole chromosome 7 and an aggressive phenotype in glioblastoma.

  11. HOXA5 could bind in the promoter of linc00312 and up-regulated the expression of it.

  12. HOXA5 was identified as a tumor suppressor gene, which inhibited non-small-cell lung cancer metastasis by regulating cytoskeletal remodeling. Its expression is repressed by linc00673 through binding with EZH2.

  13. lung cancer stem-like cells have plasticity under a condition of oxidative stress, and HOAX5 has a critical role in dedifferentiation

  14. loss of HOXA5 in mammary cells leads to loss of epithelial traits, an increase in stemness and cell plasticity, and the acquisition of more aggressive phenotypes.

  15. ATRA may inhibit the proliferation of K562 cells and promote apoptosis by upregulating the HOXA5 mRNA and protein expression.

  16. Knockdown of HOXA5 suppressed the proliferation and metastasis of esophageal squamous cell cancer cells.

  17. high expression levels of HOXA5 mRNA and protein in children with ALL indicate that HOXA5 is closely associated with childhood ALL.

  18. Downregulation of HOXA5 by shRNA may trigger apoptosis and overcome drug resistance in leukemia cells.

  19. HOXA5-induced apoptosis was p53-independent.

  20. Among the mechanosensitive genes, the two transcription factors, HoxA5 and Klf3, contain cAMP-response-elements methylation of which could serve as a mechanosensitive master switch in gene expression in atherosclerosis. (Review)

Mouse (Murine) Homeobox A5 (HOXA5) interaction partners

  1. this study shows that homeobox a5 promotes white adipose tissue browning through inhibition of the tenascin C/Toll-Like Receptor 4/Nuclear Factor Kappa B inflammatory signaling in mice

  2. these findings suggest cell autonomous roles for HOXA5 in skeletal development, as well as non-cell autonomous functions in muscle through expression in surrounding connective tissues.

  3. miR-23a cluster knockdown in calvarial osteoblasts of these mice increased the recruitment of HOXA5 and HOXA11, with a substantial enrichment of promoter histone H3 acetylation. Taken together, these findings demonstrate that the miR-23a cluster is required for maintaining stage-specific HoxA factor expression during osteogenesis.

  4. study implicates HOXA5 as a chromosome 7-associated gene-level locus that promotes selection for gain of whole chromosome 7 and an aggressive phenotype in glioblastoma.

  5. Hoxa5 expression in the mesenchyme and phrenic motor neurons controls distinct aspects of respiratory development.

  6. Hoxa5 increased adipocytes differentiation and mitochondrial biogenesis in adipocytes in vitro. CEBPbeta was determined a transcription factor of Hoxa5 and inhibited methylation level of Hoxa5 by combining on the promoter of Hoxa5.

  7. Hoxa5 possesses tissue-specific functions that differentially contribute to the morphogenesis of the respiratory tract.

  8. mapping analysis allowed us to build hypotheses regarding HOXA5 functions in the nervous system after birth, such as a potential role in the establishment and refinement/plasticity of precerebellar circuits during postnatal and adult life

  9. In presence of these inducing agents, lipid accumulation as well as expression of HoxA1, HoxA5, HoxC4 &HoxC8 markedly enhanced. Irrespective of presence or absence of T3, insulin down regulates HoxA10. T3 results in over expression of HoxA5, HoxC4 and HoxC8 genes, whereas insulin up regulates expression of only HoxC8

  10. Methylation profiling of HoxA5 gene promoter shows higher methylation in adult as compared to fetus in various somatic tissues of mouse being highest in adult spleen. However q-PCR results show higher expression during fetal stages being highest in fetal intestine followed by brain, liver and spleen. These results clearly indicate a strict correlation between DNA methylation and tissue-specific gene expression.

  11. In colon cancer, HOXA5 is downregulated, and its re-expression induces loss of the cancer stem cell phenotype, preventing tumor progression and metastasis.

  12. HoxA5 represents a novel molecule for restricting pathological and tumorigenic angiogenesis.

  13. Enforced expression of Hoxa5 in haematopoietic stem cells leads to aberrant erythropoiesis in vivo.

  14. YY1 acts as a transcriptional activator of Hoxa5 gene expression in mouse organogenesis.

  15. Hoxa5 and Hoxb5 paralog genes share some functions during lung morphogenesis; Hoxa5 plays a predominant role.

  16. Two Hox genes, Hoxa5 and Hoxc5, control diverse aspects of phrenic motor column development.

  17. Hoxa5, a stroma-specific gene, plays a significant role in ovarian biology and may be involved in ovarian cancer predisposition

  18. Hoxa5 larger transcripts may participate in the control of Hox gene expression.

  19. Hoxa5 and p53 cooperate in mammary tumorigenesis in vivo.

  20. involved in formation of pectoral girdle

HOXA5 Antigen Profile

Protein Summary

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

Gene names and symbols associated with anti-Homeobox A5 (HOXA5) Antibodies

  • homeobox A5 (HOXA5) antibody
  • homeobox A5 (Hoxa5) antibody
  • homeobox protein Hox-A5 (LOC463310) antibody
  • homeobox A5 (hoxa5) antibody
  • homeo box A5 (Hoxa5) antibody
  • hoxa5a protein (hoxa5a) antibody
  • Hox-1.3 antibody
  • hox1 antibody
  • hox1.3 antibody
  • hox1c antibody
  • Hoxa-5 antibody
  • HOXA5 antibody

Protein level used designations for anti-Homeobox A5 (HOXA5) Antibodies

homeo box 1C , homeo box A5 , homeobox protein HOXA5 , homeobox protein Hox-1C , homeobox protein Hox-A5 , homeobox protein Hox-1.3 , homeobox protein M2 , homeobox A5 , hox-1.3 , similar to Homeobox protein Hox-A5 (Hox-1.3) (M2) , hoxa5a protein , Homeobox protein Hox-A5 , LOW QUALITY PROTEIN: homeobox protein Hox-A5

GENE ID SPECIES
3202 Homo sapiens
15402 Mus musculus
463310 Pan troglodytes
482370 Canis lupus familiaris
496880 Xenopus (Silurana) tropicalis
768039 Bos taurus
100137361 Papio anubis
100499568 Sus scrofa
79241 Rattus norvegicus
700221 Macaca mulatta
100049201 Oryzias latipes
100858404 Gallus gallus
100722624 Cavia porcellus
101114518 Ovis aries
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