HOXA5 antibody (C-Term)

Catalog No. ABIN2781081

The Rabbit Polyclonal anti-HOXA5 antibody is suitable to detect HOXA5 in samples from Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for HOXA5 antibody (C-Term) (ABIN2781081)

Target: HOXA5 (Homeobox A5 (HOXA5))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HOXA5 Antibody

Binding Specificity: C-Term

Purpose: HOXA5 Antibody - C-terminal region

Sequence: FNRYLTRRRR IEIAHALCLS ERQIKIWFQN RRMKWKKDNK LKSMSMAAAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HOXA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HOXA5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39383-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXA5

Target: HOXA5 (Homeobox A5 (HOXA5))

Alternative Name: HOXA5

Background:

Background Information: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of the gene encoding HOXA5 may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Homeobox A5

Alternative Symbols: HOX1, HOX1C, HOX1.3

Protein Name: Homeobox protein Hox-A5

Molecular Weight: 29 kDa

Gene ID: 3202

NCBI Accession: NP_061975

UniProt: A2D5Y4