anti-Hyaluronan Binding Protein 2 (HABP2) Antibodies

The protein encoded by HABP2 is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. Additionally we are shipping HABP2 Proteins (17) and HABP2 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HABP2 3026 Q14520
HABP2 292126 Q6L711
HABP2 226243 Q8K0D2
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Top anti-HABP2 Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HABP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: MCF7 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB   200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Available
$363.46
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of HABP2 using HeLa whole cell lysates ABIN6272316 staining HeLa by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A549 7.5% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Porcine Liver lysate; Primary Ab: 1µg/ml Rabbit Anti-Human HABP2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western Blot at 1:1000-1:2000 dilution Lane 1: A549 whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: human liver lysate Lysates/proteins at 20 ug per lane. Western Blot at 1:2000 dilution Lane 1: human liver lysate Lane 2: mouse liver lysate Lysates/proteins at 20 ug per lane. 400 μL 2 to 3 Days
$515.63
Details

Top referenced anti-HABP2 Antibodies

  1. Human Monoclonal HABP2 Primary Antibody for IP, ELISA - ABIN516334 : Altmäe, Kallak, Fridén, Stavreus-Evers: Variation in hyaluronan-binding protein 2 (HABP2) promoter region is associated with unexplained female infertility. in Reproductive sciences (Thousand Oaks, Calif.) 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal HABP2 Primary Antibody for IHC, IHC (p) - ABIN4316533 : Bachmann, Burté, Pramana, Conte, Brown, Orimadegun, Ajetunmobi, Afolabi, Akinkunmi, Omokhodion, Akinbami, Shokunbi, Kampf, Pawitan, Uhlén, Sodeinde, Schwenk, Wahlgren, Fernandez-Reyes, Nilsson: Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria. in PLoS pathogens 2014 (PubMed)

More Antibodies against HABP2 Interaction Partners

Human Hyaluronan Binding Protein 2 (HABP2) interaction partners

  1. The G534E variant might be considered a rare polymorphism of HABP2 not associated with increased risk of familial non-medullary thyroid cancer in Brazilian kindreds.

  2. Altering fibrin clot properties by fibrinogenolysis is a novel function of FSAP in the vasculature, which facilitates clot lysis and may in vivo contribute to reduced fibrin deposition during thrombosis.

  3. three novel MD loci were identified (at P < 5 x 10(- 8)): one for percent dense volume (HABP2) and two for the absolute dense volume (INHBB, LINC01483). INHBB is an established locus for ER-negative breast cancer, and HABP2 and LINC01483 represent putative new breast cancer susceptibility loci

  4. The presence of the noninheritable V600E BRAF mutation in this family supports Knudson's "double-hit" hypothesis for cancer development and suggests the involvement of more than 1 gene in the clinical expression of familial nonmedullary thyroid carcinoma.

  5. The MI-SNP and MII-SNP FSAP gene polymorphisms were not predictive or prognostic biomarkers for coronary artery diseaseor its main risk factors.

  6. NETs bind to FSAP, but do not activate pro-FSAP unless histones are released from NETs by DNAse. This activation of FSAP is likely to be important in diminishing the cytotoxic effect of histones, thus limiting the damaging effect of NETosis.

  7. Regulation of gene expression by FSAP in vascular smooth muscle/endothelial cells accounts for its vasculo-regulatory properties.

  8. The extent of CAC in women is positively associated with total FSAP, but negatively associated with the specific activity of FSAP suggesting that FSAP may play a role in the evolution of CVD in women.

  9. Report peptide substrates used in determining substrate specificity of Factor VII activating protease.

  10. Two of 20 probands from families with history of PTC and breast carcinoma (BC) were evaluated by whole exome sequencing (WES) revealing HABP2 p.G534E.

  11. No significant association was found between rs11196288 and early-onset ischemic stroke, large artery atherosclerotic stroke, or small vessel disease stroke. rs11196288 presented significant effect on late-onset SVD stroke susceptibility in the older population.

  12. study on a wide series of familial non-medullary thyroid cancers indicates that the HABP2(G534E) variant is frequent, but does not segregate with the disease

  13. Letter: G534E variant in HABP2 is not associated with non-medullary thyroid cancer in the Spanish population.

  14. mutations were not found in familial non-medullary thyroid cancer, and the G534E variant is not the underlying genetic defect in a large sample of sporadic non-medullary thyroid cancer from the Middle East.

  15. Study showed that lower FSAP antigen plasma levels were associated with a higher chance of arterial recanalization after tissue plasminogen activator treatment, suggesting an involvement of FSAP in tissue plasminogen activator-induced clot lysis. FSAP antigen determination might be useful in predicting tissue plasminogen activator response in stroke patients.

  16. HABP2 polymorphisms are not associated with thyroid cancer.

  17. the promoter activity, which could phenocopy changes in Habp2 mRNA in response to TGF-beta, was found to be located in the 177-bp region upstream of the transcription start site, and this region did not contain any SMAD binding sites.

  18. Results show that G534E germline variant in HABP2 does not account for the familial nature of nonmedullary thyroid cancer in Australian kindreds but and is common in the general population.

  19. omology modeling suggested that the Glu-221 side chain could sterically hinder insertion of the N terminus into the HABP2 protease domain, helping to explain the detrimental effects of Glu-221 substitution on HABP2 activity.

  20. The data do not support the pathogenicity of the HABP2 c.1601G > A variant but highlight the existence of a new one that should be more extensively searched for in familial papillary thyroid carcinoma patients and its pathogenicity more carefully evaluated.

Mouse (Murine) Hyaluronan Binding Protein 2 (HABP2) interaction partners

  1. FSAP deficiency causes an increase in CCL2 expression and CCL2-mediated infiltration of leukocytes into the injured vessel

  2. the promoter activity, which could phenocopy changes in Habp2 mRNA in response to TGF-beta, was found to be located in the 177-bp region upstream of the transcription start site, and this region did not contain any SMAD binding sites.

  3. Lack of endogenous FSAP impaired the formation of stable, occlusive thrombi in mice.

  4. Results show that the lack of FSAP in mice worsens the outcome of stroke; in the absence of FSAP there was a stronger inflammatory response and lower cell survival due to insufficient activation of the PI3K/AKT pathway

  5. Lower FSAP expression is associated with enhanced liver fibrosis and inflammation in patients with chronic hepatic disorders and murine experimental liver injury.

  6. Data indicate that FSAP mediates proteolytic cleavage and activation of bone morphogenetic protein-2 (BMP-2).

  7. Hyaluronic acid binding protein 2 (HABP2) negatively regulates vascular integrity via activation of protease-activated receptor/RhoA/Rho kinase signaling. It represents a potential therapeutic target for syndromes of increased vascular permeability.

HABP2 Antigen Profile

Protein Summary

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HABP2

  • hyaluronan binding protein 2 (HABP2) antibody
  • hyaluronan binding protein 2 (habp2) antibody
  • hyaluronan binding protein 2 (Habp2) antibody
  • hyaluronic acid binding protein 2 (Habp2) antibody
  • AI035669 antibody
  • Fsap antibody
  • Habp antibody
  • habp2 antibody
  • HGFAL antibody
  • Phbp antibody

Protein level used designations for HABP2

hyaluronan binding protein 2 , hyaluronan-binding protein 2-like , factor VII activating protein , factor VII-activating protease , factor seven-activating protease , hepatocyte growth factor activator-like protein , hyaluronan-binding protein 2 , hyaluronic acid binding protein 2 , plasma hyaluronan binding protein , plasma hyaluronan-binding protein , hyaduronic acid-binding protein 2

GENE ID SPECIES
423898 Gallus gallus
450744 Pan troglodytes
477822 Canis lupus familiaris
548376 Xenopus (Silurana) tropicalis
697495 Macaca mulatta
100068293 Equus caballus
100223786 Taeniopygia guttata
100407842 Callithrix jacchus
100461891 Pongo abelii
100472238 Ailuropoda melanoleuca
100591352 Nomascus leucogenys
3026 Homo sapiens
507993 Bos taurus
292126 Rattus norvegicus
226243 Mus musculus
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