Protein Summary

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Gene names and symbols associated with IKZF3

• IKAROS family zinc finger 3 (IKZF3) antibody
• IKAROS family zinc finger 3 L homeolog (ikzf3.L) antibody
• IKAROS family zinc finger 3 (Ikzf3) antibody

• 5830411O07Rik antibody
• aio antibody
• Aiolos antibody
• IKZF3 antibody
• Zfpn1a3 antibody
• Show all synonym aliases
• Znfn1a3 antibody

Protein level used designations for IKZF3

zinc finger protein Aiolos , zinc finger protein, subfamily 1A, 3 (Aiolos) , lymphoid transcription factor , IKAROS family zinc finger 3 (Aiolos) , ikaros family zinc finger protein 3 , zinc finger protein Aiolos-like