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The protein encoded by ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. Additionally we are shipping ID1 Antibodies (78) and ID1 Proteins (7) and many more products for this protein.
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Human ID1 ELISA Kit for Sandwich ELISA - ABIN841619
Nguyen, Geens, Mertzanidou, Jacobs, Heirman, Breckpot, Spits: Gain of 20q11.21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL. in Molecular human reproduction 2014
Gain and loss of id1 function in vivo demonstrated that Id1 promotes stem cell quiescence. The increased id1 expression observed in neural stem cells in response to injury appeared independent of inflammatory signals.
a loss of CULLIN3 represents a common signaling node for controlling the activity of intracellular WNT (show WNT2 ELISA Kits) and SHH (show SHH ELISA Kits) signaling pathways mediated by ID1
These results reveal a E2F1 (show E2F1 ELISA Kits)/miR-17-92/ENH1 (show PDLIM5 ELISA Kits)/Id1 regulatory axis during myogenesis.
Id1 enables both Lewis lung carcinoma cells and the host microenvironment for an effective liver colonization.
adipose tissue-specific overexpression of Id1 causes age-associated and high-fat diet-induced obesity in mice. Id1 suppresses BAT (show BAAT ELISA Kits) thermogenesis by binding to and suppressing PGC1alpha transcriptional activity. Lack of Id1 increases beige (show LYST ELISA Kits) gene and Ucp1 (show UCP1 ELISA Kits) expression in the WAT in response to cold exposure. Furthermore, brown-like differentiation is increased in Id1-deficient mouse embryonic fibroblasts.
If Gfi1 (show ZNF163 ELISA Kits) levels fall below a threshold, Id1 expression increases and renders E2A (show TCF3 ELISA Kits) unable to function, which prevents hematopoietic progenitors from engaging along the B lymphoid lineage
Id1 may promote cell cycle progression of endothelial progenitor cells (EPCs), and that Wnt2 (show WNT2 ELISA Kits) may be important in Id1 regulation of the cell cycle of EPCs.
Differential role of Id1 in MLL (show MLL ELISA Kits)-AF9 (show MLLT3 ELISA Kits)-driven leukemia based on cell of origin
Collectively, our results suggest that ENH1 plays an important role in the activation of myogenesis through the repression of Id2 activity.
Data indicate that upregulation of E2-2 (show TCF4 ELISA Kits) protein markedly attenuated the inhibitor of DNA-binding 1 (ID1)-mediated increase in endothelial progenitor cells (EPCs) proliferation and migration.
our results strongly suggest that Usp1 (show USP1 ELISA Kits) is involved in the regulation of centrosome duplication, at least in part via ID1, and Usp1 (show USP1 ELISA Kits) may exert its oncogenic activity, partially through inducing centrosome abnormality.
Id1 enables lung cancer liver colonization by activating an epithelial mesenchymal transformation program in tumor cells and establishing the pre-metastatic niche.
High ID1 expression is associated with breast cancer.
ID1 expression impacts the sensitivity of colon cancer cells to 5-FU and may be considered as a potential predictive marker in colorectal carcinoma treatment.
Reducing ID1 gene expression reduces metastatic spread of salivary gland neoplasms.
High ID-1 expression is associated with colorectal carcinoma.
ID1 expression was positively related to drug resistance of EGFR (show EGFR ELISA Kits)-TKI in non-small cell lung cancer.
MVD was determined by immunohistochemistry, and the expressions of mRNA and protein of inhibitor of differentiation-1 (ID1) and vascular endothelial growth factor (VEGF) were detected in gastric cancer.
ID1 down-regulation induced parallel changes in the IGF and AKT (show AKT1 ELISA Kits) pathways. The crosstalk of these pathways may enhance malignant phenotypes in salivary gland cancer.
Results show that ID1, ID3 (show ID3 ELISA Kits) and IGJ (show IGJ ELISA Kits) genes are highly expressed in adult B-ALL and correlate with poor prognosis in Hispanic patients.
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
inhibitor of DNA binding 1
, DNA-binding protein inhibitor id-1
, inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
, DNA-binding protein inhibitor ID-1
, inhibitor of DNA binding 6
, Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation)
, Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation)
, class B basic helix-loop-helix protein 24
, dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein)
, inhibitor of differentiation 1
, helix-loop-helix protein