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ID1 Products

(Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1))

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The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured ID1 Categories

ID1 Antibodies

High quality antibodies with extensive validation data.

ID1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ID1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ID1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, FACS, IHC (p)
Validations
  • (6)
Cat. No. ABIN655663
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, RNAi
Validations
  • (7)
Cat. No. ABIN561408
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN561410
Quantity 100 μg
Datasheet Datasheet

Recommended ID1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975532
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967596
Quantity 96 tests
Datasheet Datasheet

Recommended ID1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1307349
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123426
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3133238
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ID1 products

Edhayan, Ohara, Stinson, Amin, Isozaki, Ha, Haines, Morgan, Campbell, Arbab, Friday, Fox, Ruth: "Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis." in: Arthritis research & therapy, Vol. 18, pp. 87, (2016) (PubMed).

Nguyen, Geens, Mertzanidou, Jacobs, Heirman, Breckpot, Spits: "Gain of 20q11.21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL." in: Molecular human reproduction, Vol. 20, Issue 2, pp. 168-77, (2014) (PubMed).

Chen, Forootan, Gosney, Forootan, Ke: "Increased expression of Id1 and Id3 promotes tumorigenicity by enhancing angiogenesis and suppressing apoptosis in small cell lung cancer." in: Genes & cancer, Vol. 5, Issue 5-6, pp. 212-25, (2014) (PubMed).

Phi, Choi, Lim, Lee, Wang, Park, Kim: "ID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma." in: BMC cancer, Vol. 13, pp. 291, (2013) (PubMed).

Fini, Monks, Farabaugh, Wright: "Contribution of xanthine oxidoreductase to mammary epithelial and breast cancer cell differentiation in part modulates inhibitor of differentiation-1." in: Molecular cancer research : MCR, Vol. 9, Issue 9, pp. 1242-54, (2011) (PubMed).

Norton, Atherton: "Coupling of cell growth control and apoptosis functions of Id proteins." in: Molecular and cellular biology, Vol. 18, Issue 4, pp. 2371-81, (1998) (PubMed).

Norton, Deed, Craggs, Sablitzky: "Id helix-loop-helix proteins in cell growth and differentiation." in: Trends in cell biology, Vol. 8, Issue 2, pp. 58-65, (1998) (PubMed).

Cooper, Brady, Bilia, Iscove, Quesenberry: "Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system." in: Blood, Vol. 89, Issue 9, pp. 3155-65, (1997) (PubMed).

Hara, Hall, Peters: "Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors." in: The EMBO journal, Vol. 16, Issue 2, pp. 332-42, (1997) (PubMed).

Langlands, Yin, Anand, Prochownik: "Differential interactions of Id proteins with basic-helix-loop-helix transcription factors." in: The Journal of biological chemistry, Vol. 272, Issue 32, pp. 19785-93, (1997) (PubMed).

Synonyms and alternative names related to ID1

inhibitor of DNA binding 1 (id1), inhibitor of DNA binding 1, HLH protein (ID1), inhibitor of DNA binding 1 (Id1), inhibitor of DNA binding 1, HLH protein (Id1), AI323524, bHLHb24, cb108, D2Wsu140e, ID, ID1, id6, ID125A, Idb1, wu:fb57e11

Protein level used designations for ID1

  • inhibitor of DNA binding 1
  • DNA-binding protein inhibitor id-1
  • inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
  • DNA-binding protein inhibitor ID-1
  • inhibitor of DNA binding 6
  • Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation)
  • Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation)
  • class B basic helix-loop-helix protein 24
  • dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein)
  • inhibitor of differentiation 1
  • helix-loop-helix protein
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