anti-Insulin-Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) Antibodies

IGF2BP1 encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. Additionally we are shipping IGF2BP1 Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IGF2BP1 10642 Q9NZI8
IGF2BP1 140486 O88477
IGF2BP1 303477 Q8CGX0
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Top anti-IGF2BP1 Antibodies at

Showing 10 out of 76 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-IGF2BP1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  HepG2 cell lysate Host:  Rabbit  Target Name:  IGF2BP1  Sample Tissue:  Rat Skeletal Muscle  Antibody Dilution:  1ug/ml 100 μL 2 to 3 Days
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-IGF2BP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL 2 to 3 Days
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
Human Goat Un-conjugated ELISA, IHC, WB ABIN571172 (0.3µg/ml) staining of K562 lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. 100 μg 6 to 7 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB IGF2BP1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. IGF2BP1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGF2BP1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL 6 to 8 Days
Human Goat Un-conjugated ELISA, WB 0.1 mg 2 to 3 Days
Cow Goat Un-conjugated ELISA, IHC, IHC (p), WB 50 μg 11 to 14 Days
Dog Rabbit Un-conjugated IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with IGF2BP1 antibody ABIN214118 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-IGF2BP1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other f ... 100 μL 11 to 14 Days
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of IGF2BP1 staining in human stomach formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with t Western blot analysis of IGF2BP1 expression in HL60 (A), K562 (B), NIH3T3 (C), mouse liver (D) whole cell lysates. 200 μL 13 to 14 Days
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days

Top referenced anti-IGF2BP1 Antibodies

  1. Human Polyclonal IGF2BP1 Primary Antibody for ELISA, WB - ABIN4321629 : Noubissi, Goswami, Sanek, Kawakami, Minamoto, Moser, Grinblat, Spiegelman: Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA. in Cancer research 2009 (PubMed)

More Antibodies against IGF2BP1 Interaction Partners

Human Insulin-Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) interaction partners

  1. Results show that p62 binds to IGF2BP1 to control the mRNA stability of FERMT2 and multiple pro-metastatic factors. This p62-RBP interaction distinguishes melanoma from other tumors where p62 controls autophagy or oxidative stress.

  2. The role of RNA-binding protein IGF2BP1 in EV-mediated promotion of melanoma metastasis.

  3. MiR-423-5p inhibited migration, invasion, and proliferation as well as induced apoptosis, by targeting IGF2BP1 trophoblasts, presenting a novel molecular basis implicated in pre-eclampsia pathogenesis.

  4. 35 SRF/IGF2BP1-dependent genes showing conserved association with SRF and IGF2BP1 expression indicate a poor overall survival probability in ovarian, liver and lung cancer. In conclusion, these findings identify the SRF/IGF2BP1-, miRNome- and m6A-dependent control of gene expression as a conserved oncogenic driver network in cancer.

  5. our data suggest that miR-150 and its downstream target IGF2BP1 may be a crucial axis for the development, progression and patients' prognosis of ostesarcoma

  6. Results found that IGF2BP1 was significantly activated in lung adenocarcinoma (LUAD) patients. Also, the expression of IGF2BP1 was significantly higher in LUAD patients with LIN28B-AS1 activation than other patients. LIN28B-AS1 alters the LIN28B mRNA stability by directly interacting with IGF2BP1.

  7. IGF2BP1 is essential for human skin squamous cell carcinoma cell survival and proliferation.

  8. Our study provides initial evidence that interaction between IMP1 and UCA1 enhances UCA1 decay and competes for miR-122-5p binding, leading to the liberation of miR-122-5p activity and the reduction of cell invasiveness.

  9. The direct binding of IGF2BPs to RNA N(6)-methyladenosine through their KH domains enhances mRNA stability and translation.

  10. The present study shows that the regulation of KRAS expression by IMP1 is complex and may involve both the IMP1 protein and its mRNA transcript.

  11. IMP1 shows alternating binding in nanocores and anomalous diffusion in the liquid phase of stress granules.

  12. Results demonstrate that IGF2BP1 plays an important role in the sensitivity of melanoma to targeted therapy. Inhibition of IGF2BP1 enhances the effects of BRAF-inhibitor and BRAF-MEK inhibitors in BRAF(V600E) melanoma. Also, knockdown of IGF2BP1 alone is sufficient to reduce tumorigenic characteristics in vemurafenib-resistant melanoma.

  13. lncRNA THOR is up-regulated in retinoblastoma, and its over-expression significantly enhances the malignant phenotype transformation of retinoblastoma cells by up-regulating c-myc and TGF2BP1 expression.

  14. SOX12 can increase the expression of CDK4 and IGF2BP1, which confer malignant phenotypes to Hepatocellular Carcinoma.

  15. report insulin-like growth factor-II binding protein 1 (IGF2BP1) as a novel interacting partner of p38 MAPK.

  16. IGF2BP1 mediates posttranscriptional loss of BCL11A in cultured human adult erythroblasts

  17. HCG11 exerted its effect on Hepatocellular carcinoma (HCC)via interaction with IGF2BP1, leading to activation of MAPK signaling, which eventually promoted the progression of HCC

  18. miR-98-5p, downregulated in HCC, inhibits proliferation while inducing apoptosis in HCC LM3 cells, partly at least, through directly targeting IGF2BP1

  19. Findings suggest a MicroRNA-140-5p (miR-140-5p)-Insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1) regulatory circuit for CC pathogenesis, and miR-140-5p may be a potential target for CC therapy.

  20. Our studies provide insights into a molecular mechanism that the positive function of IMP1 to inhibit breast tumor growth and metastasis

Mouse (Murine) Insulin-Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) interaction partners

  1. This study showed that Zipcode binding protein 1 (ZBP1) is an mRNA-binding protein that regulates the local translation of proteins, including actin, in the growth cone and is required for Shh-mediated axon guidance.

  2. The tumor-suppressive role of stromal IMP1 and its ability to modulate protumorigenic factors suggest that IMP1 status is important for the initiation and growth of epithelial tumors

  3. High CRD-BP expression is associated with Breast Tumor.

  4. Results identify IGF2BP1 as a critical translational regulator of cIAP1-mediated apoptotic resistance in rhabdomyosarcoma.

  5. This study demonstrate that ZBP1 and the phosphorylation of ZBP1 are required for attractive guidance of cortical neurons, and appropriate filopodial dynamics.

  6. IMP1 plays a role in regulating the packaging of MLV genomic RNA and can be used for improving production of retroviral vectors

  7. WAP-CRD-BP mice are a novel model for mammary neoplasia and might provide insights into human breast cancer biology.

  8. IMP-1 associates with HuD and G3BP-1 proteins in an RNA-dependent manner and binds directly to tau mRNA. We also show an RNA-dependent association between G3BP-1 and HuD proteins

Zebrafish Insulin-Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) interaction partners

  1. required during retinal ganglion cell axon outgrowth in vivo

  2. Two KH domains of CRD-BP are required for efficient binding to oncogenic mRNAs and for granule formation in zebrafish embryos.

IGF2BP1 Antigen Profile

Protein Summary

This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with IGF2BP1

  • insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1) antibody
  • insulin-like growth factor 2 mRNA binding protein 1 (Igf2bp1) antibody
  • insulin-like growth factor 2 mRNA binding protein 1 (igf2bp1) antibody
  • AL024068 antibody
  • AW549074 antibody
  • CRD-BP antibody
  • Crdbp antibody
  • D030026A21Rik antibody
  • D11Moh40e antibody
  • D11Moh45 antibody
  • IGF2BP1 antibody
  • IMP-1 antibody
  • Imp1 antibody
  • Neilsen antibody
  • VICKZ1 antibody
  • wu:fi72a06 antibody
  • Zbp1 antibody
  • zgc:152963 antibody

Protein level used designations for IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1 , IGF-II mRNA-binding protein 1 , IGF2 mRNA-binding protein 1 , IMP-1 , VICKZ family member 1 , ZBP-1 , insulin-like growth factor 2 mRNA-binding protein 1 , zip code-binding protein 1 , zipcode-binding protein 1 , coding region determinant-binding protein , coding region determinant binding protein , insulin-like growth factor 2, binding protein 1 , zipcode binding protein 1 , B-actin zipcode-binding protein 1 , insulin-like growth factor 2 binding protein 1 , rZBP-1 , zipcode-binding protein-1

455198 Pan troglodytes
100018704 Monodelphis domestica
100055918 Equus caballus
395953 Gallus gallus
10642 Homo sapiens
491064 Canis lupus familiaris
516853 Bos taurus
140486 Mus musculus
303477 Rattus norvegicus
558182 Danio rerio
100620940 Sus scrofa
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