anti-Insulinoma-Associated 1 (INSM1) Antibodies

Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. Additionally we are shipping Insulinoma-Associated 1 Kits (5) and Insulinoma-Associated 1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
INSM1 3642 Q01101
INSM1 53626 Q63ZV0
INSM1 100912563  
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Top anti-Insulinoma-Associated 1 Antibodies at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-INSM1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Human Lung 100 μL Log in to see 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-INSM1 Antibody Titration:  1.25ug/ml  Positive Control:  Human Cerebellum Human Heart 100 μL Log in to see 2 to 3 Days
$249.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 2 to 3 Days
$446.88
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 100 μL Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 1 to 2 Days
$394.90
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant INSM1, Mouse. Used in DAB staining on fromalin fixed paraffin- embedded kidney tissue 100 μg Log in to see 15 to 18 Days
$360.00
Details
Mouse Rabbit Un-conjugated IF/ICC, IHC, IP, WB Western blot analysis of recombinant Mouse INSM1. IHC-P analysis of kidney tissue, with DAB staining. 100 μg Log in to see 11 to 18 Days
$440.62
Details

More Antibodies against Insulinoma-Associated 1 Interaction Partners

Human Insulinoma-Associated 1 (INSM1) interaction partners

  1. INSM1 is a novel sensitive and specific marker for detection of small cell carcinoma of the prostate.

  2. specificity of INSM1 for neuroendocrine neoplasms as a group was 100%. INSM1 staining was concordant with surgical pathology specimens in all 20 paired cases

  3. Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors.

  4. INSM1 may be used as a standalone first-line marker of neuroendocrine differentiation for tumors of the head and neck.

  5. INSM1 is highly expressed in small-cell lung carcinomas.

  6. Our results suggest that INSM1 is a useful immunohistochemical marker for diagnosing pancreatic neuroendocrine tumor.

  7. INSM1 is a sensitive marker for Merkel cell carcinoma

  8. Our data suggest that children with the INSM1 binding site within the CLDN14 risk haplotype have a higher likelihood of hypercalciuria and kidney stones. Enhanced CLDN14 expression may play a role in the pathophysiology of their hypercalciuria.

  9. High INSM1 expression is associated with small-cell lung cancer.

  10. Suggest that INSM1 is valuable for identification of the high-grade thoracic neuroendocrine carcinomas that are sometimes negative for synaptophysin, chromogranin, and CD56.

  11. Solution NMR structure of zinc finger 4 and 5 from human INSM1 has been presented.

  12. INSM1 is closely related to the development of high-grade neuroendocrine carcinoma of uterine cervix, and a useful new neuroendocrine marker in conducting its correct and rapid diagnosis

  13. Data supports our hypothesis that a positive-feedback loop of sonic hedgehog signaling induced INSM1 through N-myc and INSM1 enhanced N-myc stability contributing to the transformation of human neuroblastoma.

  14. Small cell lung cancer tissues were strongly positive for INSM1. INSM1 signal was not detected on normal adjacent tissues from lung cancer patients or normal lung tissues

  15. the INSM1-promoter specific conditional replicating adenovirus represents a sensitive diagnostic tool to aid clinicians in the detection of NE tumors.

  16. Insulinoma-Associated Protein 1 is a crucial regulator of neuroendocrine differentiation in lung cancer.

  17. INSM1 autoantibodies were associated with risk of developing type 1 diabetes.

  18. INSM1 expression was significantly increased in Neuroendocrine neoplastic vs nonneoplastic tissue.

  19. Both the AR42J cell line and the primary cultured mouse acinar cells support role for INSM1 in pancreatic acinar cell trans-differentiation model.

  20. The results suggest that INSM1 up-regulation plays a positive role in HSV-1 replication, probably by binding to the ICP0 promoter.

Mouse (Murine) Insulinoma-Associated 1 (INSM1) interaction partners

  1. We conclude that decreases in Insm1 interfere with beta-cell specification during the early postnatal period and impair glucose homeostasis during metabolic stress in adults. Insm1 levels are therefore a factor that can influence the development of diabetes.

  2. An INSM1/RCOR1/2 complex controls the balance of proliferation and differentiation during brain development.

  3. INSM1 ectopic expression impairs normal lung development especially in postnatal alveologenesis.

  4. Insm1 is the earliest known gene expressed in outer versus inner hair cells, demonstrating that nascent outer hair cells initiate a unique differentiation program in the embryo, much earlier than previously believed.

  5. Insm1-dependent Hes1 repression is required for neuroendocrine development.

  6. INSM1 interacts with RACK1 protein and facilitates insulin receptor -mediated signaling.

  7. Insm1 works to promote endocrine cell differentiation in a pathway that involves Neurog3 and Ripply3

  8. Data suggest that IA-2 and IA-2beta play important roles in regulation of circadian rhythm, likely through neurochemical communication among neurons of suprachiasmatic nucleus. [Insm2-beta; IA-2beta; insulinoma-associated protein 2-beta]

  9. Insm1 acts in the epigenetic and transcriptional network that controls differentiation of endocrine cells in the anterior pituitary gland, and that it requires the SNAG domain to exert this function in vivo.

  10. This study suggested that Insm1 in promoting the transition of progenitors from apical and proliferative to basal, terminal and neuronogenic.

  11. isolation, characterization, and identification of an interacting protein, Cbl-associated protein (CAP)

  12. IA-1 gene is developmentally expressed in the nervous system and the NeuroD1/E47 transcription factors up-regulate IA-1 gene expression through the proximal E-box element of the IA-1 promoter

  13. Pancreatic and intestinal endocrine cells express Insm1 and require Insm1 for their development.

  14. The fetal lethality of Insm1 mutant mice is caused by catecholamine deficiency, which highlights the importance of Insm1 in the development of the sympatho-adrenal lineage.

  15. in mice and humans, INSM1 is likewise expressed transiently during terminal neurogenic divisions, from late progenitors to nascent neurons, and particularly during symmetric neuronogenic divisions.

  16. Insm1 and Nhlh1/NSCL1 are novel HH targets induced by Shh treatment in cultured cerebellar granule cell progenitors.

  17. INSM1 is a new zinc-finger transcription factor that modulates insulin gene transcription during early pancreas development.

  18. Insulinoma-associated 1 is expressed specifically in progenitors undergoing neurogenic divisions, has a panneurogenic role throughout the brain, and promotes basal progenitor formation in the neocortex.

  19. a conserved cis-regulatory sequence associated with Insm1 is bound by Ascl1 in the hindbrain, and Ascl1 is essential for the expression of Insm1 in the ventral hindbrain

Zebrafish Insulinoma-Associated 1 (INSM1) interaction partners

  1. Insm1a-deficient embryos were microphthalmic and displayed defects in rod and cone photoreceptor differentiation

  2. Analaysis of the data identified Insm1a as a key regulator of retina regeneration and provide a mechanistic understanding of how Insm1a contributes to multiple phases of this process.

  3. characterization of two zebrafish Insm1-like genes, insm1a and insm1b, and analysis of their expression patterns during embryonic development

Xenopus laevis Insulinoma-Associated 1 (INSM1) interaction partners

  1. insm1 is expressed in regions of the tadpole brain and retina harboring populations of progenitor cells.

  2. results reveal that IA1 constitutes a novel player downstream of Xash1 in the formation of a previously unidentified population of Xenopus noradrenergic primary neurons

Insulinoma-Associated 1 (INSM1) Antigen Profile

Protein Summary

Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors.

Gene names and symbols associated with INSM1

  • INSM transcriptional repressor 1 (INSM1) antibody
  • insulinoma-associated 1 (Insm1) antibody
  • insulinoma-associated 1b (insm1b) antibody
  • insulinoma associated 1 (insm1) antibody
  • insulinoma associated 1 L homeolog (insm1.L) antibody
  • INSM transcriptional repressor 1 (Insm1) antibody
  • insulinoma-associated 1a (insm1a) antibody
  • fc13a09 antibody
  • ia-1 antibody
  • IA1 antibody
  • INSM-1 antibody
  • INSM1 antibody
  • wu:fc13a09 antibody
  • zgc:63866 antibody
  • zgc:77257 antibody
  • zINSM-1 antibody

Protein level used designations for INSM1

insulinoma-associated protein 1 , zinc finger protein IA-1 , insulinoma-associated protein (IA-1) , insulinoma-associated 1 , insulinoma-associated 1-like protein b , insuloma-associated 1 , insulinoma-associated protein 1-like , LOW QUALITY PROTEIN: insulinoma-associated protein 1 , Insulinoma-associated 1-like protein a , Zinc finger protein IA-1a , insulinoma-associated 1-like protein a , insulinoma-associated protein 1a , zinc finger protein IA-1a

GENE ID SPECIES
3642 Homo sapiens
53626 Mus musculus
323882 Danio rerio
738566 Pan troglodytes
779614 Xenopus (Silurana) tropicalis
100126605 Xenopus laevis
100137721 Bos taurus
607566 Canis lupus familiaris
100912563 Rattus norvegicus
108176704 Oryctolagus cuniculus
100511966 Sus scrofa
106782417 Equus caballus
402941 Danio rerio
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