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The protein encoded by ILKAP is a protein serine/threonine phosphatase of the PP2C family.
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Human Polyclonal ILKAP Primary Antibody for WB - ABIN1881459
Nakrieko, Vespa, Mason, Irvine, DSouza, Dagnino: Modulation of integrin-linked kinase nucleo-cytoplasmic shuttling by ILKAP and CRM1. in Cell cycle (Georgetown, Tex.) 2008
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Human Polyclonal ILKAP Primary Antibody for WB - ABIN529323
Zhou, Cao, Yang, Cong, Wang, Chen, Yin, Wu, Cai, Liu, Xiao: Characterization of nuclear localization signal in the N terminus of integrin-linked kinase-associated phosphatase (ILKAP) and its essential role in the down-regulation of RSK2 protein signaling. in The Journal of biological chemistry 2013
our data suggest an essential role of PINCH1 (show LIMS1 Antibodies), ILK (show ILK Antibodies) and ILKAP for the radioresistance of p53 (show TP53 Antibodies)-wildtype glioblastoma multiforme cells
The expression of ILKAP was considerably lower in eutopic and ectopic endometrial samples from women with endometriosis than in control endometrium. Expression varied depending on the phase of the menstrual cycle.
Data show involvement of ANXA5 (show ANXA5 Antibodies) and ILKAP in susceptibility to malignant melanoma
ILKAP is a nuclear protein (show RDBP Antibodies) that regulates cell survival and apoptosis through the regulation of RSK2 (show RPS6KA3 Antibodies) signaling.
these results suggested that palladin (show PALLD Antibodies) played a specific role in modulating the subcellular localization of the cytoplasmic ILKAP and promoting the ILKAP-induced apoptosis.
These studies demonstrate the importance for keratinocyte proliferation of ILK (show ILK Antibodies) regulation through changes in its subcellular localization, and establish ILKAP and CRM1 (show XPO1 Antibodies) as pivotal modulators of ILK (show ILK Antibodies) subcellular distribution and activity in these cells.
The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.
integrin-linked kinase-associated serine/threonine phosphatase 2C
, integrin-linked kinase-associated protein phosphatase 2C
, integrin-linked kinase-associated serine/threonine phosphatase 2C-like
, integrin-linked kinase-associated serine/threonine phosphatase
, integrin-linked kinase associated phosphatase
, protein phosphatase 2c, delta isozyme
, protein phosphatase 2C