anti-Interferon Regulatory Factor 2 (IRF2) Antibodies

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. Additionally we are shipping Interferon Regulatory Factor 2 Proteins (16) and Interferon Regulatory Factor 2 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IRF2 3660 P14316
IRF2 16363 P23906
IRF2 290749  
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Top anti-Interferon Regulatory Factor 2 Antibodies at antibodies-online.com

Showing 10 out of 150 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184810 staining (2µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-IRF2 Antibody Titration:  5.0ug/ml  Positive Control:  Jurkat cell lysate 100 μL 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μg 4 to 6 Days
$240.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-IRF2 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate Rabbit Anti-IRF2 Antibody   Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB ABIN6274172 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6274172 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. 100 μL 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB 100 μg 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from Jurkat/COLO205 cells, using IRF2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using IRF2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of IRF2 Antibody (Center) in Jurkat cell line lysates (35ug/lane). This demonstrates the IRF2 antibody detected the IRF2 protein (arrow). Western blot analysis of IRF2 Antibody (Center) in mouse bladder tissue lysates (35ug/lane). This demonstrates the IRF2 antibody detected the IRF2 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Mouse Lung Tissue; Lane2: Mouse Large Intestine Tissue; Lane3: Human Hela Cells; Lane4: Human Jurkat Cells. Figure. Western Blot; Sample: Recombinant IRF2, Mouse. 100 μg 15 to 18 Days
$360.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$493.17
Details

Top referenced anti-Interferon Regulatory Factor 2 Antibodies

  1. Human Polyclonal IRF2 Primary Antibody for ELISA, WB - ABIN546908 : Liljeroos, Vuolteenaho, Rounioja, Henriques-Normark, Hallman, Ojaniemi: Bacterial ligand of TLR2 signals Stat activation via induction of IRF1/2 and interferon-alpha production. in Cellular signalling 2008 (PubMed)

  2. Human Polyclonal IRF2 Primary Antibody for ELISA, WB - ABIN249629 : Harada, Kitagawa, Tanaka, Yamamoto, Harada, Ishihara, Taniguchi: Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2. in Science (New York, N.Y.) 1993 (PubMed)

More Antibodies against Interferon Regulatory Factor 2 Interaction Partners

Human Interferon Regulatory Factor 2 (IRF2) interaction partners

  1. This review focusses on current knowledge of the roles of IRF-1 and IRF-2 in human cancer, with particular attention paid to the impact of IRF-1 inactivation.

  2. Data suggest that MIR1290 expression is remarkably upregulated in non-small-cell lung carcinoma tissues compared to adjacent normal lung tissues; IRF2 appears to be a direct target of MIR1290. (MIR1290 = microRNA-1290; IRF2 = interferon regulatory factor-2)

  3. These finding suggests that miR-302b inhibits key transcription factors and cytokines by targeting ERBB4, IRF2 and CXCR4, implicating its role in the inhibition of CRI in EC.

  4. Our study primarily suggests IRF-2 as a potential prognostic biomarker in colorectal cancer

  5. The effects of IRF2 suppresses non-small cell lung cancer by promoting cell apoptosis, inhibiting cell proliferation and migration ability.

  6. In a genome wide are study to identify acute kidney injury risk in critically ill patients, the locus on chromosome 4, located 150 kb upstream of IRF2 was identified to regulate immunity pathways related to kidney disease risk gene APOL1. Disruption of IRF-2 has been found to up-regulate the inflammatory response to infection.

  7. Study shows that IRF2 knockdown inhibits growth, colony formation of OCI/AML-2, OCI/AML-3, and THP-1 cells. In addition, IRF2 knockdown induces apoptosis of acute myeloid leukemia (AML) cells by regulating apoptotic effectors. Further mechanism analysis shows that INPP4B contributes to the effects of IRF2 on apoptosis and growth of AML cells. Thus, IRF2 serves as an important regulator in AML by targeting INPP4B.

  8. miR-450 targets IRF2 and thus supresses lung cancer cell proliferation and invasion.

  9. It might play as a tumor suppressor by regulating P53 signaling in gastric cancer.

  10. the association of IRF2 with susceptibility to systemic lupus erythematosus

  11. IRF2genes were not associated with pancreatitis. 4 variants were found: c.123G>A (novel), c.651C>T, c.744G>A, and c.638C>T, p.P213L.

  12. Data suggest that interferon regulatory factors 1 and 2 (IRF1 and IRF2) may serve as potential targets of therapy.

  13. miR-221 directly inhibits the expression of SOCS3 and IRF2.

  14. KGF could up-regulate IL-7 expression through the STAT1/IRF-1, IRF-2 signaling pathway, which is a new insight in potential effects of KGF on the intestinal mucosal immune system.

  15. IFN regulatory factor 2 (Irf2) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3

  16. IRF2 overexpression protects against I/R injury by decreasing IRF1-dependent injury and may represent a novel therapeutic strategy.

  17. The results suggested that distinct markers in IRF2 may be associated with atopic dermatitis and eczema herpeticum (which may depend upon ethnic ancestry) and genetic variants in IRF2 may contribute to an abnormal immune response to herpes simplex virus.

  18. these results suggest that IRF-2 plays an important role in the tumorigenesis of pancreatic cancer and down-regulation of IRF-2 would be a new treatment target for pancreatic cancer.

  19. IRF-2 activates the HPV-16 P97 promoter in vivo.

  20. IRF-2 activates RIG-I promoter through ISRE-like site as well as IRF-1 and IFN-alpha stimulation.

Mouse (Murine) Interferon Regulatory Factor 2 (IRF2) interaction partners

  1. our data suggest that IRF2 is an important regulator of the proinflammatory response in macrophages by controlling HIF-1alpha-dependent glycolytic gene expression and glycolysis.

  2. Data show that HCFC2 is a critical component of the IRF1 and IRF2 transcriptional machinery that regulates Tlr3 gene expression.

  3. Mysm1 enhanced function of the IRF2 and IRF8 promoters, suggesting that Mysm1 governs the IRFs for hematopoietic stem cell homeostasis.

  4. Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion

  5. Chimeric IRF-2 binds with IRF-E motif and VREbeta but not with VREalpha1.

  6. KGF could up-regulate IL-7 expression through the STAT1/IRF-1, IRF-2 signaling pathway, which is a new insight in potential effects of KGF on the intestinal mucosal immune system.

  7. IFN regulatory factor 2 (Irf2) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3

  8. These results revealed a multi-faceted role of IRF-2 in the function of B cells, particularly B2 cells, through regulating proliferation in an IFNAR-dependent manner and antibody production via up-regulation of Blimp-1.

  9. In mice doubly deficient forIRF-2 and CD1d, the overall memory phenotype T cell population is contrastingly enlarged.

  10. IRF2 regulates exocytosis in pancreatic acinar cells; defects in this process might be involved in the early phases of acute pancreatitis.

  11. Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells.

  12. Irf2 has an important role in vitro in the regulation of COX-2 expression by LPS.

  13. IRF-2 is acetylated in a cell growth-dependent manner, which enables it to contribute to transcription of cell growth-regulated promoters

  14. IRF-2 is a critical transacting factor that regulates in vivo responses to lipopolysaccharide, with a novel anti-apoptotic role.

  15. In the absence of IRF-2, uterine natural killer (uNK) cells are normal in number and function, but there is a serious deficiency of peripheral NK cells.

  16. IFN regulatory factor 2 is involved in the negative regulation of IFN-alpha/beta signaling.

  17. Binding affinity of IRF-2 is similar to that of IRF-1 and B lymphocyte-induced maturation protein-1 (Blimp-1) for functionally important regulatory sites containing the consensus sequence GAAAG.

  18. IRF-2 is involved in up-regulation of nonmuscle myosin heavy chain II-A gene expression in cell differentiation

  19. Differential peripheral and central natural killer (NK) cell deficiencies in IRF-2 knockout mice reveal a novel late checkpoint for NK cell maturation, distinct from the early IL-15-dependent expansion stage.

  20. the negative regulatory role of IRF-2 on the basophil population size is critically important for preventing excess Th2 polarization and the Th1/Th2 balance in naive animals

Interferon Regulatory Factor 2 (IRF2) Antigen Profile

Protein Summary

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.

Gene names and symbols associated with IRF2

  • interferon regulatory factor 2 (IRF2) antibody
  • interferon regulatory factor 2 (Irf2) antibody
  • interferon regulatory factor 2 (irf2) antibody
  • interferon regulatory factor 2 L homeolog (irf2.L) antibody
  • 9830146E22Rik antibody
  • AI646973 antibody
  • irf-2 antibody
  • irf2b antibody
  • zgc:103451 antibody

Protein level used designations for IRF2

regulatory factor 2 , interferon responsive factor 2 , interferon regulatory factor 2b

GENE ID SPECIES
3660 Homo sapiens
396115 Gallus gallus
475633 Canis lupus familiaris
337916 Bos taurus
16363 Mus musculus
290749 Rattus norvegicus
494071 Danio rerio
495990 Xenopus laevis
100621620 Sus scrofa
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