Interferon-Induced Transmembrane Protein 1 Proteins (IFITM1)

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Additionally we are shipping IFITM1 Antibodies (109) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat IFITM1 IFITM1 293618  
IFITM1 8519 P13164
IFITM1 68713 Q9D103
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Top IFITM1 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,626.01
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,355.45
Details
Escherichia coli (E. coli) Human GST tag Interferon-Induced Transmembrane Protein 1 (IFITM1) (AA 1-36) protein (GST tag) 1 mg Log in to see 60 to 71 Days
$1,842.50
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
Details
Wheat germ Human Un-conjugated   10 μg Log in to see 11 to 12 Days
$654.29
Details

IFITM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Interferon-Induced Transmembrane Protein 1 (IFITM1) Interaction Partners

Human Interferon-Induced Transmembrane Protein 1 (IFITM1) interaction partners

  1. Strong ifitm1 Expression in CD4 (show CD4 Proteins) T Cells in HIV Controllers Is Correlated With Immune Activation

  2. Using a multi-group heat map from GSE9716 analysis of the GEO database, IFITM1 was determined to be a relevant radioresistance gene. Inhibition of IFITM1 in combination with radiotherapy could, indeed, inhibit oral neoplasm cells.

  3. Identification of three distinct mutations that converted IFITM1 or IFITM3 (show IFITM3 Proteins) from inhibitors to enhancers of MERS-CoV or SARS (show SARS Proteins)-CoV spike protein-mediated entry revealed key structural motifs or residues determining the biological activities of IFITM proteins.

  4. Epithelial-mesenchymal transition (EMT (show ITK Proteins)) signature was dysregulated by both loss and gain of function of IFITM1, which was partially reverted by Caveolin-1 (CAV1 (show CAV1 Proteins)).

  5. These results indicate that IFITM1 protein can restrict alphavirus infection by inhibiting viral fusion with cellular membranes.

  6. The transcriptional regulation of IFITM1, 2 and 3 expression.

  7. IFITM1 and IFITM3 (show IFITM3 Proteins) inhibit Zika virus infection early in the viral life cycle.

  8. IFITM1 suppression blocks proliferation and invasion of aromatase (show CYP19A1 Proteins) inhibitor-resistant breast cancer in vivo by JAK (show JAK3 Proteins)/STAT1 (show STAT1 Proteins)-mediated induction of p21 (show CDKN1A Proteins).

  9. Compared with CD10 (show MME Proteins), IFITM1 has superior performance distinguishing endometrial stroma of adenomyosis from mesenchyma surrounding invasive endometrial adenocarcinoma.

  10. Overexpression of IFITM1 is associated with Oral Squamous Cell Carcinomas.

Mouse (Murine) Interferon-Induced Transmembrane Protein 1 (IFITM1) interaction partners

  1. the importance of the C-terminal region of IFITM1 in modulating the antiviral function through controlling protein subcellular localization.

  2. Palmitoylation of IFITM1 regulates protein stability by preventing proteasomal degradation, and modification of the nonconserved cysteine at the IFITM1 C terminus supports an intramembrane topology with implications for anti-influenza A virus activity.

  3. the fact that IFITM1 can function as a negative regulator of cell proliferation, and because the gene maps to chromosome band 11p15.5, previously associated with NSCLC, it is likely that IFITM1 in man has a key role in tumor formation

  4. Fragilis2 regulates epithelialization of the somites and paraxial mesoderm formation.

  5. The antiproliferative action of IFN-gamma (show IFNG Proteins) requires the induction of IFITM1.

IFITM1 Protein Profile

Protein Summary

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53- dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

Gene names and symbols associated with IFITM1

  • interferon induced transmembrane protein 1 (Ifitm1)
  • interferon induced transmembrane protein 1 (IFITM1)
  • interferon induced transmembrane protein 1 (9-27) (IFITM1)
  • 9-27 protein
  • 1110036C17Rik protein
  • CD225 protein
  • DSPA2a protein
  • IFI17 protein
  • LEU13 protein
  • Mil-2 protein
  • Mil2 protein

Protein level used designations for IFITM1

interferon-induced transmembrane protein 1 , interferon induced transmembrane protein 1 (9-27) , interferon induced transmembrane protein 1 , dispanin subfamily A member 2a , interferon-induced protein 17 , interferon-inducible protein 9-27 , leu-13 antigen , fragilis protein 2 , fragilis2 , ifitm-like protein 2 , interferon induced transmembrane protein 2 like , interferon-induced membrane protein Leu-13/9-27 , interferon-induced transmembrane protein 1 (9-27) , interferon-induced transmembrane protein 1 (9-27) isoform 1

GENE ID SPECIES
293618 Rattus norvegicus
100455800 Pongo abelii
100526663 Pan troglodytes
8519 Homo sapiens
68713 Mus musculus
697687 Macaca mulatta
353510 Bos taurus
Selected quality suppliers for IFITM1 Proteins (IFITM1)
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