IFITM1 Protein (AA 1-36, Extracellular) (GST tag)
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- Target See all IFITM1 Proteins
- IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular, AA 1-36
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IFITM1 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MHKEEHEVAV LGAPPSTILP RSTVINIHSE TSVPDH
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product IFITM1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
- Alternative Name
- IFM1 (IFITM1 Products)
- Synonyms
- 9-27 Protein, CD225 Protein, DSPA2a Protein, IFI17 Protein, LEU13 Protein, 1110036C17Rik Protein, Mil-2 Protein, Mil2 Protein, interferon induced transmembrane protein 1 Protein, interferon induced transmembrane protein 1 (9-27) Protein, Ifitm1 Protein, IFITM1 Protein
- Background
- IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation
- Molecular Weight
- 31.3 kDa
- UniProt
- P13164
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