Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IFITM1 Protein (AA 1-36, Extracellular) (GST tag)

IFITM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5712123
  • Target See all IFITM1 Proteins
    IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
    Protein Type
    Recombinant
    Protein Characteristics
    Extracellular, AA 1-36
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IFITM1 protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MHKEEHEVAV LGAPPSTILP RSTVINIHSE TSVPDH
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product IFITM1 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
    Alternative Name
    IFM1 (IFITM1 Products)
    Synonyms
    9-27 Protein, CD225 Protein, DSPA2a Protein, IFI17 Protein, LEU13 Protein, 1110036C17Rik Protein, Mil-2 Protein, Mil2 Protein, interferon induced transmembrane protein 1 Protein, interferon induced transmembrane protein 1 (9-27) Protein, Ifitm1 Protein, IFITM1 Protein
    Background
    IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation
    Molecular Weight
    31.3 kDa
    UniProt
    P13164
You are here:
Support