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The protein encoded by IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. Additionally we are shipping IL16 Kits (97) and IL16 Proteins (68) and many more products for this protein.
Showing 10 out of 207 products:
Human Polyclonal IL16 Primary Antibody for ELISA (Detection), FACS - ABIN4900560
Böttcher, Jenmalm, Björkstén, Garofalo: Chemoattractant factors in breast milk from allergic and nonallergic mothers. in Pediatric research 2000
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Human Polyclonal IL16 Primary Antibody for Func, ELISA - ABIN2474940
Cruikshank, Center, Nisar, Wu, Natke, Theodore, Kornfeld: Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biologic function with CD4 expression. in Proceedings of the National Academy of Sciences of the United States of America 1994
Show all 2 Pubmed References
Data indicate an association between interleukin-16 (IL-16) rs4072111 and rs1131445 with progression to the severe stages (III-IV) of endometriosis.
Long-term exposure to tobacco smoke does not markedly alter extracellular concentrations of IL-16 protein in blood. However, it does decrease the intracellular IL-16 concentrations in blood NK cells.
data revealed an association between circulating IL-16 and severity of psoriasis which indicates that this cytokine could serve as a potential marker of disease activity. However, further investigations are required
Structure of a Potential Therapeutic Antibody Bound to Interleukin-16
No significant differences were observed in rs11556218 genotype frequencies between the study groups. In conclusion, the results of our study reveal an association between the IL-16 rs4778889 polymorphism and heightened risk of renal cell cancer .
We found that the rs1131445 T/C and rs4072111 T/C variants of IL-16 were significantly associated with increased risk of gastric cancer in Iranian population.
Data indicate that high interleukin-16 (IL-6 (show IL6 Antibodies)), interferon-gamma (IFN-gamma (show IFNG Antibodies)) and low interleukin-15 (IL-15 (show IL15 Antibodies)) levels suggest active tuberculosis.
the results of our study suggested an association between the IL-16 rs4778889 polymorphism and an elevated risk of renal cell carcinoma (show MOK Antibodies)
We observed highly significant reductions in the concentration of circulating interleukin (IL)-16, IL-7 (show IL7 Antibodies), and Vascular Endothelial Growth Factor A (VEGF-A (show VEGFA Antibodies)) in encephalomyelitis/chronic fatigue syndrome patients.
IL-16 rs1131445 C/T polymorphism is related to the susceptibility to cancer in Asians (meta-analysis)
The production of IL-16 contributed to lung damage as neutralization of IL-16 enhanced S. aureus clearance and resulted in diminished lung pathology in S. aureus pneumonia.
Data indicate that knockdown of translocator protein TSPO (show TSPO Antibodies) by siRNAhad showed no effect on the productions of TNF-alpha (show TNF Antibodies), IL-1beta (show IL1B Antibodies) and IL-6 (show IL6 Antibodies) in lipopolysaccharide (LPS (show TLR4 Antibodies))-stimulated BV-2 microglia cells.
Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.
Data show overexpression of pro-IL-16 impaired resting B cell proliferation mediated through regulating nuclear factor (NF)-kappaB activation, and siRNA knock-down of pro-IL-16 expression decreased the level of p27(kip) and increased the level of Skp2.
We determined that ovalbumin (show OVA Antibodies) (OVA)-sensitized mice have an increase in systemic tumor necrosis factor-alpha (show TNF Antibodies) levels, and that serum or BAL fluid stimulation of bronchial epithelial cells results in production of IL-16
IL-16 induces a greater migratory response in the Th1 (show HAND1 Antibodies) cell subset than in the Th2 subset.
interleukin-16 and its precursor have roles in T lymphocyte activation and growth [review]
IL-16 precursor mRNA and protein expression are dynamically regulated during CD4 (show CD4 Antibodies)+ T cell activation by a calcineurin-dependent mechanism; pro-IL-16 may influence T cell cycle regulation, although not in a dominant manner.
Caspase-3 (show CASP3 Antibodies) mediated production of IL-16 by infiltrating CD4 (show CD4 Antibodies)+ T cells, contributes to ongoing neuroinflammation by chemoattraction of additional waves of CD4 (show CD4 Antibodies)+ T cells.
After femoral artery ligation, CD8 (show CD8A Antibodies)+ T cells infiltrate the site of collateral vessel growth and recruit CD4 (show CD4 Antibodies)+ mononuclear cells through the expression of IL-16
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
, interleukin 16 (lymphocyte chemoattractant factor)
, lymphocyte chemoattractant factor
, neuronal interleukin 16
, prointerleukin 16