anti-Interleukin 17A (IL17A) Antibodies

The protein encoded by IL17A is a proinflammatory cytokine produced by activated T cells. Additionally we are shipping IL17A Proteins (89) and IL17A Kits (50) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL17A 3605 Q16552
IL17A 16171 Q62386
IL17A 301289  
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Top anti-IL17A Antibodies at

Showing 10 out of 264 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Mouse Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using IL17A antibody. 100 μL 13 to 14 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-IL17A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate WB Suggested Anti-IL17A  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: MCF7 cell lysate 100 μL 2 to 3 Days
Mouse Rabbit Un-conjugated ELISA, WB Western blot analysis of IL-17 using anti- IL-17 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane : Recombinant Mouse IL-17 Protein 0.5ng After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- IL-17 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for IL-17 at approximately 30KD. The expected band size for IL-17 is at 30KD. 100 μg 4 to 6 Days
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of IL17A (arrow) using Interleukin-17A (IL17A) Antibody ; 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the IL17A gene. 0.4 mL 6 to 8 Days
Human Mouse Un-conjugated IHC, IHC (p), WB 50 μg 11 to 14 Days
Human Mouse Biotin FACS, WB Western Blot of Mouse Anti-IL-17A antibody Lane 1: human full length recombinant IL-17A protein Lane 2: mouse full length recombinant IL-17A protein Lane 3: rat full length recombinant IL-17A protein Load: 20 ng/lane Primary antibody: Anti-IL-17A antibody at 1ug/mL for overnight at 4°C 100 μg 5 to 7 Days
Rat Rabbit Biotin ELISA, WB Western Blot showing detection of Rat IL-17A. 50ng of Rat IL-17A (Lane 1) was run on a 4-20% gel and transferred to 0.45 µm nitrocellulose. After blocking with 5% Blotto  30 min at 20°C, Anti-Rat IL-17A (RABBIT) Antibody Biotin Conjugated  secondary antibody was used at 1:5000 in Blocking Buffer for Fluorescent Western Blotting . HRP Streptavidin  was used at 1:40,000 in ABIN925618 for 30 min at 20°C and imaged using the Bio-Rad 4000 MP. Arrow indicates correct 15 kDa molecular weight position expected for Rat IL-17A. 100 μg 5 to 7 Days
Human CHO Cells Un-conjugated BR, ELISA, FACS, IP, WB   100 μL 7 to 8 Days
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB Western blot analysis of extracts of hela , using IL17A antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276397 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days

Top referenced anti-IL17A Antibodies

  1. Human Polyclonal IL17A Primary Antibody for CyTOF, FACS - ABIN4900592 : Todd, Simpson, Estis, Torres, Wub: Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays. in Cytokine 2013 (PubMed)
    Show all 43 Pubmed References

  2. Mouse (Murine) Polyclonal IL17A Primary Antibody for CyTOF, FACS - ABIN4899637 : Otani, Watanabe, Tanigawa, Okazaki, Yamagami, Watanabe, Tominaga, Fujiwara, Oshitani, Arakawa: Anti-inflammatory effects of IL-17A on Helicobacter pylori-induced gastritis. in Biochemical and biophysical research communications 2009 (PubMed)
    Show all 11 Pubmed References

  3. Mouse (Murine) Polyclonal IL17A Primary Antibody for IF, IHC - ABIN3021082 : Zhang, Mao, Zhou, Cheng, Lin: IL-17A contributes to brain ischemia reperfusion injury through calpain-TRPC6 pathway in mice. in Neuroscience 2014 (PubMed)
    Show all 7 Pubmed References

  4. Human Polyclonal IL17A Primary Antibody for IF, IHC - ABIN6672244 : Zhang, Zhao, Song, Yang, Zhang, Zhang, Li: Differential Health Effects of Constant versus Intermittent Exposure to Formaldehyde in Mice: Implications for Building Ventilation Strategies. in Environmental science & technology 2018 (PubMed)
    Show all 7 Pubmed References

  5. Human Monoclonal IL17A Primary Antibody for Neut - ABIN786712 : Aarvak, Chabaud, Miossec, Natvig: IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 6 Pubmed References

  6. Human Monoclonal IL17A Primary Antibody for Neut - ABIN786714 : Chabaud, Durand, Buchs, Fossiez, Page, Frappart, Miossec: Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. in Arthritis and rheumatism 1999 (PubMed)
    Show all 6 Pubmed References

  7. Mouse (Murine) Monoclonal IL17A Primary Antibody for ELISA, WB - ABIN2689740 : Coquet, Chakravarti, Kyparissoudis, McNab, Pitt, McKenzie, Berzins, Smyth, Godfrey: Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 4 Pubmed References

  8. Human Polyclonal IL17A Primary Antibody for ELISA, ICC - ABIN6262537 : Yan, Yang, Han, Feng: Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats. in Molecular medicine reports 2016 (PubMed)
    Show all 3 Pubmed References

  9. Human Monoclonal IL17A Primary Antibody for FACS - ABIN4898004 : Coury, Annels, Rivollier, Olsson, Santoro, Speziani, Azocar, Flacher, Djebali, Tebib, Brytting, Egeler, Rabourdin-Combe, Henter, Arico, Delprat: Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. in Nature medicine 2008 (PubMed)
    Show all 3 Pubmed References

  10. Mouse (Murine) Monoclonal IL17A Primary Antibody for ICS, Neut - ABIN1177292 : Prussin, Metcalfe: Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. in Journal of immunological methods 1996 (PubMed)
    Show all 3 Pubmed References

More Antibodies against IL17A Interaction Partners

Human Interleukin 17A (IL17A) interaction partners

  1. Elevated IL-17 and SOCS3 levels were identified in lupus patients. There were higher IL-17 levels in lupus nephritis (class IV) than in SLE without renal involvement.

  2. In conclusion, the polymorphisms of IL-17A rs2275913 and rs3819024 and the haplotype containing these two SNPs influenced the susceptibility to syphilis in a Han Chinese population.

  3. In a case-control study comparing overweight/obese women with women of normal weight, the IL17 AA genotype was related to the PCOS susceptibility in women of normal weight.

  4. IL-17A and IL-32 SNPs might be associated with predisposition to polycystic ovary syndrome in Iranian women.

  5. study indicates that IL-17A enhances proliferation and osteogenic differentiation of SHED by regulating OPG/RANKL mechanism thus suggests therapeutic potential of IL-17A in bone regeneration.

  6. These data suggest that a gene signature of IL-17 airway epithelial response distinguishes a biologically, radiographically, and clinically distinct COPD subgroup that may benefit from personalized therapy.

  7. rs4711998 and rs8193036 polymorphisms not associated with bronchiolitis at less than six months of age or postbronchiolitis asthma at 11-13 years of age

  8. Kinases SphK1 and SphK2 regulate IL-17 expression in human T cells.

  9. pneumococcal carriage initiates an IL-17A-mediated immune response in nasopharyngeal adenoids

  10. IL-17A may be a target for future CRC immunotherapy.

  11. PD-1(+)CD4(+) T cells with reduced proliferative capacity and increased transforming growth factor-beta (TGF-beta)/interleukin-17A (IL-17A) expression were detected in idiopathic pulmonary fibrosis.

  12. IL-17A-inhibited autophagy is related to Bcl2 degradation in hepatocellular carcinoma (HCC) cells. Bcl2 may be degraded via the autophagosome-lysosome pathway in HCC cells.

  13. this study shows that IL-6 and type-I collagen production by Systemic Sclerosis fibroblasts are differentially regulated by IL-17A in the presence of TGF-beta 1

  14. there was a significant difference in the serum levels of IL-6 and IL-17a between patients and controls, and the elevated levels of these two cytokines associated significantly with poor outcome in breast cancer patients and, therefore, can be used as prognostic markers.

  15. Opioid requirements during and after orthognathic surgery are enhanced in carriers of the AA genotype of the rs2275913 SNP of the IL-17A gene.

  16. This review elaborated the relationship between IFN-gamma and IL-17 in the progress of periodontitis, providing new explanations into the development of periodontitis and alveolar bone destruction caused by the host immune response [review]

  17. Study demonstrated that rs763780 CC functional polymorphism of IL-17A as well as IL-17 serum levels are significantly related to the risk of knee osteoarthritis susceptibility in Han Chinese population.

  18. IL-17 and CD40L synergistically mediate the inflammatory response and remodelling associated with tissue injury and glomerular sclerosis in diabetic nephropathy.

  19. IL-17A -737T/C, -444A/G, -197G/A, and -121G/A SNPs are not risk factors for rheumatoid arthritis, but the IL-17A TAGA haplotype is a risk factor for systemic lupus erythematosus.

  20. this study shows that IL-17A attenuates IFN-lambda expression by inducing suppressor of cytokine signaling expression in airway epithelium

Horse (Equine) Interleukin 17A (IL17A) interaction partners

  1. Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO) horses.

  2. cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells

  3. This study examined effects of in vitro exposure to solutions of hay dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

  4. The acute pulmonary neutrophilia characteristic of recurrent airway obstruction was not associated with an increase in expression of chemokines in pulmonary mononuclear cells from disease-susceptible horses.

Mouse (Murine) Interleukin 17A (IL17A) interaction partners

  1. these results support a protective role of HDAC2 in HDM-induced airway inflammation by suppressing IL-17A production and might suggest that activation of HDAC2 and/or inhibition of IL-17A production could prevent the development of allergic airway inflammation.

  2. During lung inflammation, IL-33 and leukotrienes synergistically induce ILC217s. ILC217s are a highly pathogenic and unexpected source for IL-17 in lung inflammation.

  3. B cells produced high levels of the tissue-protective protein, Resistin-like molecule alpha (RELMalpha), which then downregulated IL-17A expression.

  4. Secretion of interleukin (IL)-17A, IL-17F, IL-1beta, and interferon-gamma was increased upon exposure lymphoid cells to Giardia lamblia.

  5. computational analysis identified IL-17A's early, central organizing role in the rapid evolution of a network of inflammatory mediators that induce neutrophil infiltration and neutrophil extracellular trap formation responsible for hepatic damage after liver ischemia reperfusion

  6. key roles for TNF and, to a lesser extent, IL-17 as mediators of liver inflammation and fibrosis induced by constitutive NLRP3 inflammasome activation in myeloid-derived cells.

  7. Arid5a orchestrates a feed-forward amplification loop, which promoted IL-17 signaling by controlling mRNA stability and translation

  8. The results indicated that S100A9 gene silencing suppressed the release of pro-inflammatory cytokines through blocking of the IL-17 pathway in acute pancreatitis (AP).

  9. IL-17A contributed to an enhanced inflammatory response during the coinfection with Leishmania major and Staphylococcus aureus in a mouse model.

  10. In serum of human IL-1c transgenic mice, IL-6 and IL-17 levels significantly increased, and signal transducer and activator of transcription 3 (Stat3) was activated in joints.

  11. GLK induces IL-17A transcription by activating AhR and ROR-gammat.GLK controls IL-17A production and autoimmune responses through AhR.

  12. these data suggest a mechanism in which macrophage ATF3 promotes IL-17A production in gammadelta T cells to rapidly induce host defenses during early S. pneumoniae infection.

  13. IL-17A modulates apoptosis of osteoclast precursors through Beclin1-autophagy-TRAF3 signaling pathway, thereby influencing osteoclastogenesis.

  14. In conclusion, these results demonstrate that eosinophils control IL-17-mediated response and contribute to lung pathology after Aspergillus fumigatus infection.

  15. Via noncanonical Wnt signaling and IL-17A-related pathways.

  16. Combination treatment of IL-17A mAb.

  17. IL17 role in the lung mucous cell hyperplasia caused by respiratory syncytial virus infection.

  18. Pre-pregnancy exposure to diesel exhaust predisposes offspring to asthma through IL-1beta and IL-17A.

  19. study revealed that miR-340 can specifically bind to the 3' untranslated region of mouse IL-17A and downregulate the expression of endogenous IL-17A.

  20. revealed that IL-17 induced the infiltration of a specific subtype of macrophages to aggravate fibrosis through an monocyte chemotactic protein-dependent mechanism

Cow (Bovine) Interleukin 17A (IL17A) interaction partners

  1. These results support previous gene transcription studies and extend the observation of increased IL-22 and IL-17A responses in M. bovis-infected animals to the level of protein production.

  2. calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.

  3. Data show that CD4(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.

  4. IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.

  5. IL-17A and IL-17F have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.

  6. The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.

Pig (Porcine) Interleukin 17A (IL17A) interaction partners

  1. At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.

  2. Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.

  3. conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3(+)CD4(+) and CD3(+)gammadeltaTCR(+).

  4. Cloning and expression of interleukin-17.

Rhesus Monkey Interleukin 17A (IL17A) interaction partners

  1. Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.

Guinea Pig Interleukin 17A (IL17A) interaction partners

  1. molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.

Rabbit Interleukin 17A (IL17A) interaction partners

  1. one of the interaction sites between IL17A and its receptor IL17RA

IL17A Antigen Profile

Protein Summary

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Gene names and symbols associated with anti-Interleukin 17A (IL17A) Antibodies

  • interleukin 17A (IL17A) antibody
  • interleukin 17A (Il17a) antibody
  • ChIL-17 antibody
  • CTLA-8 antibody
  • Ctla8 antibody
  • IL-17 antibody
  • IL-17A antibody
  • IL-17F antibody
  • Il17 antibody
  • IL17A antibody

Protein level used designations for anti-Interleukin 17A (IL17A) Antibodies

CTLA-8 , cytotoxic T-lymphocyte-associated antigen 8 , cytotoxic T-lymphocyte-associated protein 8 , interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) , interleukin-17A , interleukin 17 , IL-17A , interleukin 17A , IL-17 , interleukin-17 , Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

3605 Homo sapiens
100034142 Equus caballus
16171 Mus musculus
282863 Bos taurus
395111 Gallus gallus
449530 Sus scrofa
472029 Pan troglodytes
481837 Canis lupus familiaris
708123 Macaca mulatta
301289 Rattus norvegicus
100735572 Cavia porcellus
100339322 Oryctolagus cuniculus
100860877 Capra hircus
101103931 Ovis aries
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