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The protein encoded by IL17A is a proinflammatory cytokine produced by activated T cells. Additionally we are shipping IL17A Kits (114) and IL17A Proteins (94) and many more products for this protein.
Showing 10 out of 511 products:
Human Polyclonal IL17A Primary Antibody for CyTOF, FACS - ABIN4900592
Todd, Simpson, Estis, Torres, Wub: Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays. in Cytokine 2013
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Mouse (Murine) Polyclonal IL17A Primary Antibody for CyTOF, FACS - ABIN4899637
Otani, Watanabe, Tanigawa, Okazaki, Yamagami, Watanabe, Tominaga, Fujiwara, Oshitani, Arakawa: Anti-inflammatory effects of IL-17A on Helicobacter pylori-induced gastritis. in Biochemical and biophysical research communications 2009
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Human Monoclonal IL17A Primary Antibody for Neut - ABIN786714
Aarvak, Chabaud, Miossec, Natvig: IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. in Journal of immunology (Baltimore, Md. : 1950) 1999
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Human Monoclonal IL17A Primary Antibody for - ABIN786713
Chabaud, Durand, Buchs, Fossiez, Page, Frappart, Miossec: Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. in Arthritis and rheumatism 1999
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Human Monoclonal IL17A Primary Antibody for Neut - ABIN786712
Chabaud, Fossiez, Taupin, Miossec: Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. in Journal of immunology (Baltimore, Md. : 1950) 1998
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Mouse (Murine) Monoclonal IL17A Primary Antibody for ELISA, WB - ABIN2689740
Coquet, Chakravarti, Kyparissoudis, McNab, Pitt, McKenzie, Berzins, Smyth, Godfrey: Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population. in Proceedings of the National Academy of Sciences of the United States of America 2008
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Mouse (Murine) Monoclonal IL17A Primary Antibody for ICS, Neut - ABIN1177292
Prussin, Metcalfe: Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. in Journal of immunological methods 1996
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Human Monoclonal IL17A Primary Antibody for FACS - ABIN4898004
Coury, Annels, Rivollier, Olsson, Santoro, Speziani, Azocar, Flacher, Djebali, Tebib, Brytting, Egeler, Rabourdin-Combe, Henter, Arico, Delprat: Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. in Nature medicine 2008
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Human Monoclonal IL17A Primary Antibody for FACS - ABIN4898003
Alisa, Boswell, Pathan, Ayaru, Williams, Behboudi: Human CD4(+) T cells recognize an epitope within alpha-fetoprotein sequence and develop into TGF-beta-producing CD4(+) T cells. in Journal of immunology (Baltimore, Md. : 1950) 2008
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Human Monoclonal IL17A Primary Antibody for BP, FACS - ABIN4324658
Wen, Wan, Ren, Zhou, Gao, Wu, Wang, Yuan, Zhou: Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway. in Experimental and molecular pathology 2016
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Serum IL-23 (show IL23A Antibodies) and IL-17 levels were elevated in patients with aneurysmal subarachnoid hemorrhage (aSAH (show ASAH1 Antibodies)) showing upregulation of IL-23 (show IL23A Antibodies)/IL-17 inflammatory axis after aSAH (show ASAH1 Antibodies). Serum IL-23 (show IL23A Antibodies) and IL-17 showed differential correlations with post hemorrhagic complications and no correlation with clinical outcome.
More prominent IL-17 and IFN-gamma (show IFNG Antibodies) production by all lymphocyte subsets in Behcet disease (BD) might be associated with the increased innate responses, early tissue neutrophil infiltrations and late adaptive immunity in BD.
Data showed that IL-17A levels were sustained in respiratory samples from cystic fibrosis (show S100A8 Antibodies) patients infected by P. aeruginosa. IL-17 mediated-immunity plays a double-edged found during chronic airways infection: in one hand, it contributes to the control of P. aeruginosa burden, modulating host resistance, while, on the other, it alters host tolerance, propagating exacerbated pulmonary neutrophilia and tissue remodeling.
gamma delta T cells, rather than Th17cells, are the principal producers of IL-17 in acute gouty arthritis patients during the acute gout flares.
In dermatomyositis muscle specimens, IL-4 (show IL4 Antibodies) and IFN-g (show IFNG Antibodies) levels were positively correlated, while no correlation was observed between IL-17 and the other two cytokines. Moreover, IL-4 (show IL4 Antibodies) and IFNg (show IFNG Antibodies) levels were significantly negative correlated with muscle strength grades for the deltoid muscle
high expression of both IL17A and IL32 (show IL32 Antibodies) leads to enhancement of T cell responses in breast tumors
IL-17 responds to human Vgamma9Vdelta2 T lymphocytes by TLR-activated plasmacytoid dendritic cells
data suggest that suppression of IL-17 A production as one of the mechanisms underlying the beneficial effect of first-line disease-modifying treatments is stronger in glatiramer acetate than in interferon-beta (show IFNB1 Antibodies)
There was a close correlation between the expression of IL-17 and syndecan-1 (show SDC1 Antibodies) in nasal mucosa epithelial cells, glandular epithelial cells, and inflammatory cells, suggesting that IL-17 and syndecan-1 (show SDC1 Antibodies) may play a role, and interact with each other, in the pathogenesis of non- eosinophilic chronic rhinosinusitis with nasal polyps.
Findings indicate that IL17A -197 G/A and IL23R (show IL23R Antibodies) H3Q are not associated with susceptibility to MM. However, IL-17 and IL-23R (show IL23R Antibodies) polymorphisms may affect severity, bone lesions, and extra-medullary disease in patients with MM.
Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (show AOC2 Antibodies)) horses.
cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells
This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Antibodies) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
The hormone levels are significantly reduced and lymphocytic infiltration in the lacrimal gland in ovariectomized mice, whereas the frequency of Th17 cells in the blood and spleen and IL-17A and IL-23 (show IL23A Antibodies) expression in the lacrimal glands are increased, leading to reduced tear production and positive fluorescein staining in the cornea.
the results suggest that IL-17A induces podocyte injury by activating the NLRP3 (show NLRP3 Antibodies) inflammasome and IL-1beta (show IL1B Antibodies) secretion and contributes to disruption of the kidney's filtration system.
These results suggest that a low concentration of IL-17A is likely to promote autophagic activity via activating RANKL (show TNFSF11 Antibodies)-JNK (show MAPK8 Antibodies) pathway during osteoclastogenesis.
study shows that IL-17A plays an important role in comorbid depression associated with psoriatic inflammation, where both NFkappaB and p38MAPK (show MAPK14 Antibodies) pathways play significant roles via upregulation of inflammatory mediators in the brain
the present study demonstrated that IL-17A crucially regulated the wound healing process and that accelerated neutrophil accumulation caused by IL-17A led to the delayed wound repair.
The results emphasize the importance of IL-17 in experimental autoimmune myasthenia gravis development and that IL-17 independent pathways drive the autoimmune reaction.
In estrogen receptor (show ESR1 Antibodies) negative breast cancer cells targeting of IL-17A inhibited PDL1 (show CD274 Antibodies) expression in the tumor microenvironment, decreasing the percentage of Treg cells in tumor-infiltrating lymphocytes, and promoting CD4 (show CD4 Antibodies)+ and CD8 (show CD8A Antibodies)+ T cells to secrete interferon gamma (show IFNG Antibodies).
Report provides evidence that IL-17 can promote Lewis lung carcinoma growth through inhibition of myeloid-derived suppressor cells apoptosis, which maybe dependent on ERK1/2 signaling pathway.
Suggest that the IL-17A/IL-10 (show IL10 Antibodies)/STAT3 (show STAT3 Antibodies) signaling pathway plays a crucial role in the pathogenesis of hepatic fibrosis by suppressing hepatocellular autophagy and that blocking this pathway may provide therapeutic benefits for the treatment of hepatic fibrosis.
these data provide novel insight into a dynamic IL-17A-CXCR2 (show CXCR2 Antibodies)-neutrophil axis during acute segmented filamentous bacteria colonization and demonstrate a central role for neutrophils in limiting segmented filamentous bacteria expansion
calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.
Data show that CD4 (show CD4 Antibodies)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.
IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.
IL-17A and IL-17F (show IL17F Antibodies) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.
The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.
At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (show CD8A Antibodies)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.
Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.
conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (show CD3 Antibodies)(+)CD4 (show CD4 Antibodies)(+) and CD3 (show CD3 Antibodies)(+)gammadeltaTCR(+).
Cloning and expression of interleukin-17.
Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.
molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.
one of the interaction sites between IL17A and its receptor IL17RA (show IL17RA Antibodies)
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
, cytotoxic T-lymphocyte-associated antigen 8
, cytotoxic T-lymphocyte-associated protein 8
, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, interleukin 17
, interleukin 17A
, Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)