anti-Interleukin 17A (IL17A) Antibodies

Human Interleukin 17A (IL17A) interaction partners

1. the expression of IFN-gamma (show IFNG Antibodies) and IL-17 was also suppressed by IRAK1 (show IRAK1 Antibodies)/4 inhibitor both in active Behcet's patients and in normal subjects.

2. Polymorphisms of IL-17 are associated with host susceptibility to some bacterial pathogen. [review]

3. secreted IL-17A is not responsible for the second hit in acute pancreatitis

4. In carriage, an increased IL-17 and IFN-gamma (show IFNG Antibodies) levels were observed following stimulation with S. aureus strains.

5. The levels of salivary IL-6 (show IL6 Antibodies) and IL-17 were increased significantly in calculus associated Chronic periodontitis patients.

6. IL17A G197A is associated with a higher susceptibility of developing OLP and these patients seem to present a considerable increase in IL17A serum levels.

7. These findings highlight a regulatory pathway of Tiam1/Rac1 in Th17 cells and suggest that it may be a therapeutic target in multiple sclerosis.

8. Interleukin 17A (IL-17[G197G]) was associated with preterm birth (PTB (show PTBP1 Antibodies)), and the PTB (show PTBP1 Antibodies) group had lower IL-17A expression compared to the full-term group .

9. In studies of mouse and human pancreatic tumors and precursors, we found that immune cell-derived IL17 regulated development of tuft cells and stem cell features of pancreatic cancer cells via increased expression of DCLK1 (show DCLK1 Antibodies), POU2F3 (show POU2F3 Antibodies), ALDH1A1 (show ALDH1A1 Antibodies), and IL17RC (show IL17RC Antibodies).

10. We observed that IL-6 (show IL6 Antibodies), IL-17A and NO production in the tears and sera of all patients was strongly associated with inflammatory infiltration, NOS2, NF-kappaB (show NFKB1 Antibodies) and Bcl2 (show BCL2 Antibodies) expression in pterygia biopsies. Collectively, our results indicate a relationship between local inflammation and anti-apoptotic processes in pterygium disease, leading to both tissue damage and enhanced cellular proliferation.

Horse (Equine) Interleukin 17A (IL17A) interaction partners

1. Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (show AOC2 Antibodies)) horses.

2. cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells

3. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Antibodies) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

Mouse (Murine) Interleukin 17A (IL17A) interaction partners

1. blocking activin (show Actbeta Antibodies)/ACVR2A (show ACVR2A Antibodies) impaired the potency of hepatic stellate cells to produce collagens in response to IL17s.

2. this study shows the positive effects of IL-17 on the early-stage differentiation and negative effects on the calcification of primary osteoblasts in vitro

3. these data suggest that IL-17A promotes DVT pathogenesis by enhancing platelet activation and aggregation, neutrophil infiltration, and EC activation

4. These findings highlight a regulatory pathway of Tiam1/Rac1 in Th17 cells and suggest that it may be a therapeutic target in multiple sclerosis.

5. DAPK (show DAPK1 Antibodies) deficiency leads to excess HIF-1a (show HIF1A Antibodies) accumulation, enhanced IL-17 expression and exacerbated experimental autoimmune encephalomyelitis.

6. decreased COX-2 (show COX2 Antibodies) and IL-17 levels were observed in both groups treated with Nintedanib in the prostate anterior lobe. Thus, we concluded that Nintedanib was effective in delaying tumor progression and, despite not directly acting on inflammation, Nintedanib may adversely affect inflammatory pathways, favoring prostate cancer delay

7. In studies of mouse and human pancreatic tumors and precursors, we found that immune cell-derived IL17 regulated development of tuft cells and stem cell features of pancreatic cancer cells via increased expression of DCLK1 (show DCLK1 Antibodies), POU2F3 (show POU2F3 Antibodies), ALDH1A1 (show ALDH1A1 Antibodies), and IL17RC (show IL17RC Antibodies).

8. The reaction of IL-17A in the acute lung injury induced by LPS (show TLR4 Antibodies) is stronger than that by PQ.

9. IL17A promoted osteoblast differentiation and calcification in a partly AKT2dependent manner in MC3T3E1 cells in vitro, possibly reflecting compensation by other signaling pathways. The results of the present study may offer novel perspectives to guide the clinical strategy for the prevention and treatment of periodontitis

10. Mechanistically, CREB (show CREB1 Antibodies), activated by CD3 (show CD3E Antibodies)-PKC (show PKC Antibodies)- signaling, plays a key role in regulating Th17 cell differentiation, at least in part through directly binding to the Il17-Il17f gene locus.

Cow (Bovine) Interleukin 17A (IL17A) interaction partners

1. These results support previous gene transcription studies and extend the observation of increased IL-22 (show IL22 Antibodies) and IL-17A responses in M. bovis-infected animals to the level of protein production.

2. calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.

3. Data show that CD4 (show CD4 Antibodies)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.

4. IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.

5. IL-17A and IL-17F (show IL17F Antibodies) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.

6. The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.

Pig (Porcine) Interleukin 17A (IL17A) interaction partners

1. At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (show CD8A Antibodies)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.

2. Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.

3. conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (show CD3 Antibodies)(+)CD4 (show CD4 Antibodies)(+) and CD3 (show CD3 Antibodies)(+)gammadeltaTCR(+).

4. Cloning and expression of interleukin-17.

Rhesus Monkey Interleukin 17A (IL17A) interaction partners

1. Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.

Guinea Pig Interleukin 17A (IL17A) interaction partners

1. molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.

Rabbit Interleukin 17A (IL17A) interaction partners

1. one of the interaction sites between IL17A and its receptor IL17RA (show IL17RA Antibodies)