anti-Interleukin 17A (IL17A) Antibodies

The protein encoded by IL17A is a proinflammatory cytokine produced by activated T cells. Additionally we are shipping IL17A Kits (118) and IL17A Proteins (95) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL17A 3605 Q16552
IL17A 16171 Q62386
IL17A 301289  
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Top anti-IL17A Antibodies at antibodies-online.com

Showing 10 out of 405 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated CyTOF, FACS, ICC, IHC, IP, Neut, WB Detection of IL-17 in Human PBMCs by Flow Cytometry. Immunoprecipitation of Human IL-17. 100 μg Log in to see 8 to 9 Days
$463.45
Details
Mouse Rabbit Un-conjugated ELISA, WB Western blot analysis of IL-17 using anti- IL-17 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane : Recombinant Mouse IL-17 Protein 0.5ng After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- IL-17 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for IL-17 at approximately 30KD. The expected band size for IL-17 is at 30KD. 100 μg Log in to see 4 to 6 Days
$240.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-IL17A Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>MCF7 cell lysate WB Suggested Anti-IL17A <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rat Biotin ELISA, WB   0.5 mg Log in to see 15 to 18 Days
$561.35
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB   100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Mouse Biotin FACS, WB Western Blot of Mouse Anti-IL-17A antibody Lane 1: human full length recombinant IL-17A protein Lane 2: mouse full length recombinant IL-17A protein Lane 3: rat full length recombinant IL-17A protein Load: 20 ng/lane Primary antibody: Anti-IL-17A antibody at 1ug/mL for overnight at 4°C 100 μg Log in to see 7 to 9 Days
$389.00
Details
Mouse Rat Un-conjugated WB Western Blot showing detection of Mouse IL-17A. 100 ng of Mouse IL-17A was run on a 4-20% gel and transferred to 0.45 µm nitrocellulose. After blocking with 1% BSA-TTBS , diluted to 1X) 30 min at 20°C, Anti-Mouse IL-17A (RAT) Antibody  was used at 1:1000 in 1% BSA-TTBS over night at 4°C. Peroxidase conjugated Rabbit Anti-mouse  secondary antibody was diluted in Blocking Buffer for Fluorescent Western Blotting  at 1:40,000 for 30 min at 20°C and imaged using the Bio-Rad 4000 MP. Band indicates correct 23 kDa molecular weight position expected for Mouse IL-17A. monoclonal anti IL-17A was used to detect IL17A and separate Mouse CD4+ Cells by flow cytometry. Mouse CD4+ T cells were isolated from freshly dissected spleen by centrifugation in T cell separation media and selected by magnetic separation. Cells were grown on plates coated with anti-CD3 antibody, and stimulated with: 5 µg/mL anti-CD28, 10 ng/mL IL-1beta, 50 ng/mL mouse IL-6, 1 ng/mL TGFbeta1 and 10 µg/mL anti-mouse IFN? over 8-10 days of culture. Cells were incubated for 15-20 minutes with Add rat anti-mouse CD4 APC at a concentration of 0.125 µg/mL, washed, fixed and permeabilized and incubated with  Rat anti mouse IL-17A monoclonal Antibody (210-501-B32) or controls as shown. Cells were washed, incubated in streptavidin conjugated PE, fixed and analyzed by Flow cytometry. Shown here are results for ’s monoclonal anti mouse IL-17A antibody (210-501-B32) 100 μg Log in to see 7 to 9 Days
$389.00
Details
Mouse Goat Un-conjugated CyTOF, FACS, Neut, WB Detection of IL-17 in EL-4 Mouse Cell Line by Flow Cytometry. EL-4 mouse lymphoblast cell line was treated for 16 hours with 50 ng/mL PMA then stained with Goat Anti-Mouse IL-17 Antigen Affinity-purified Polyclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. IL-6 Secretion Induced by IL-17 and Neutralization by Mouse IL-17 Antibody. Recombinant Mouse IL-17. The ND50 is typically 0.05-0.25 ug/mL. 100 μg Log in to see 8 to 9 Days
$422.05
Details
Rat Rabbit HRP ELISA, WB Western Blot of Rabbit anti-Rat IL-17A Antibody Peroxidase Conjugated. Lane 1: Recombinant Rat IL-17A. Load: 50 ng per lane. Primary antibody: Rabbit anti-Rat IL-17A Antibody Peroxidase Conjugated at 1:1,000 o/n at 4°C. Secondary antibody: none. Block: ABIN925618 for 30 minutes at RT. Predicted/Observed size: 17 kDa, 17 kDa for Rat IL-17A. 100 μg Log in to see 7 to 9 Days
$389.00
Details
Human Mouse Un-conjugated FACS, WB Western Blot of Mouse Anti-IL-17A antibody Lane 1: human full length recombinant IL-17A protein Lane 2: mouse full length recombinant IL-17A protein Lane 3: rat full length recombinant IL-17A protein Load: 20 ng/lane Primary antibody: Anti-IL-17A antibody at 1ug/mL for overnight at 4°C Western Blot results of Mouse Anti-IL-17A Antibody. Lane 1: Opal Prestained Molecular Weight Ladder . Lane 2: IL-17A. Load: 50ng. Primary Antibody: Mouse Anti-IL-17A at 1µg/mL overnight at 4°C. Secondary Antibody: Rabbit anti-Mouse HRP  at 1:40,000 for 30min at RT. Blocking: BlockOut  for 30 min at RT. 100 μg Log in to see 7 to 9 Days
$389.00
Details

Top referenced anti-IL17A Antibodies

  1. Human Polyclonal IL17A Primary Antibody for CyTOF, FACS - ABIN4900592 : Todd, Simpson, Estis, Torres, Wub: Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays. in Cytokine 2013 (PubMed)
    Show all 40 Pubmed References

  2. Mouse (Murine) Polyclonal IL17A Primary Antibody for CyTOF, FACS - ABIN4899637 : Otani, Watanabe, Tanigawa, Okazaki, Yamagami, Watanabe, Tominaga, Fujiwara, Oshitani, Arakawa: Anti-inflammatory effects of IL-17A on Helicobacter pylori-induced gastritis. in Biochemical and biophysical research communications 2009 (PubMed)
    Show all 10 Pubmed References

  3. Human Monoclonal IL17A Primary Antibody for Neut - ABIN786712 : Aarvak, Chabaud, Miossec, Natvig: IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 6 Pubmed References

  4. Human Monoclonal IL17A Primary Antibody for Neut - ABIN786714 : Chabaud, Durand, Buchs, Fossiez, Page, Frappart, Miossec: Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. in Arthritis and rheumatism 1999 (PubMed)
    Show all 6 Pubmed References

  5. Human Monoclonal IL17A Primary Antibody for - ABIN786713 : Chabaud, Fossiez, Taupin, Miossec: Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 6 Pubmed References

  6. Mouse (Murine) Monoclonal IL17A Primary Antibody for ELISA, WB - ABIN2689740 : Coquet, Chakravarti, Kyparissoudis, McNab, Pitt, McKenzie, Berzins, Smyth, Godfrey: Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 4 Pubmed References

  7. Mouse (Murine) Monoclonal IL17A Primary Antibody for ICS, Neut - ABIN1177292 : Prussin, Metcalfe: Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. in Journal of immunological methods 1996 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal IL17A Primary Antibody for FACS - ABIN4898004 : Coury, Annels, Rivollier, Olsson, Santoro, Speziani, Azocar, Flacher, Djebali, Tebib, Brytting, Egeler, Rabourdin-Combe, Henter, Arico, Delprat: Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. in Nature medicine 2008 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal IL17A Primary Antibody for ELISA, ICC - ABIN6262537 : Yan, Yang, Han, Feng: Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats. in Molecular medicine reports 2016 (PubMed)
    Show all 3 Pubmed References

  10. Mouse (Murine) Polyclonal IL17A Primary Antibody for ELISA, WB - ABIN3042799 : Li, Pan, Qiu: Imbalances of Th17 and Treg cells and their respective cytokines in COPD patients by disease stage. in International journal of clinical and experimental medicine 2015 (PubMed)
    Show all 2 Pubmed References

More Antibodies against IL17A Interaction Partners

Human Interleukin 17A (IL17A) interaction partners

  1. the expression of IFN-gamma (show IFNG Antibodies) and IL-17 was also suppressed by IRAK1 (show IRAK1 Antibodies)/4 inhibitor both in active Behcet's patients and in normal subjects.

  2. Polymorphisms of IL-17 are associated with host susceptibility to some bacterial pathogen. [review]

  3. secreted IL-17A is not responsible for the second hit in acute pancreatitis

  4. In carriage, an increased IL-17 and IFN-gamma (show IFNG Antibodies) levels were observed following stimulation with S. aureus strains.

  5. The levels of salivary IL-6 (show IL6 Antibodies) and IL-17 were increased significantly in calculus associated Chronic periodontitis patients.

  6. IL17A G197A is associated with a higher susceptibility of developing OLP and these patients seem to present a considerable increase in IL17A serum levels.

  7. These findings highlight a regulatory pathway of Tiam1/Rac1 in Th17 cells and suggest that it may be a therapeutic target in multiple sclerosis.

  8. Interleukin 17A (IL-17[G197G]) was associated with preterm birth (PTB (show PTBP1 Antibodies)), and the PTB (show PTBP1 Antibodies) group had lower IL-17A expression compared to the full-term group .

  9. In studies of mouse and human pancreatic tumors and precursors, we found that immune cell-derived IL17 regulated development of tuft cells and stem cell features of pancreatic cancer cells via increased expression of DCLK1 (show DCLK1 Antibodies), POU2F3 (show POU2F3 Antibodies), ALDH1A1 (show ALDH1A1 Antibodies), and IL17RC (show IL17RC Antibodies).

  10. We observed that IL-6 (show IL6 Antibodies), IL-17A and NO production in the tears and sera of all patients was strongly associated with inflammatory infiltration, NOS2, NF-kappaB (show NFKB1 Antibodies) and Bcl2 (show BCL2 Antibodies) expression in pterygia biopsies. Collectively, our results indicate a relationship between local inflammation and anti-apoptotic processes in pterygium disease, leading to both tissue damage and enhanced cellular proliferation.

Horse (Equine) Interleukin 17A (IL17A) interaction partners

  1. Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (show AOC2 Antibodies)) horses.

  2. cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells

  3. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Antibodies) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

Mouse (Murine) Interleukin 17A (IL17A) interaction partners

  1. blocking activin (show Actbeta Antibodies)/ACVR2A (show ACVR2A Antibodies) impaired the potency of hepatic stellate cells to produce collagens in response to IL17s.

  2. this study shows the positive effects of IL-17 on the early-stage differentiation and negative effects on the calcification of primary osteoblasts in vitro

  3. these data suggest that IL-17A promotes DVT pathogenesis by enhancing platelet activation and aggregation, neutrophil infiltration, and EC activation

  4. These findings highlight a regulatory pathway of Tiam1/Rac1 in Th17 cells and suggest that it may be a therapeutic target in multiple sclerosis.

  5. DAPK (show DAPK1 Antibodies) deficiency leads to excess HIF-1a (show HIF1A Antibodies) accumulation, enhanced IL-17 expression and exacerbated experimental autoimmune encephalomyelitis.

  6. decreased COX-2 (show COX2 Antibodies) and IL-17 levels were observed in both groups treated with Nintedanib in the prostate anterior lobe. Thus, we concluded that Nintedanib was effective in delaying tumor progression and, despite not directly acting on inflammation, Nintedanib may adversely affect inflammatory pathways, favoring prostate cancer delay

  7. In studies of mouse and human pancreatic tumors and precursors, we found that immune cell-derived IL17 regulated development of tuft cells and stem cell features of pancreatic cancer cells via increased expression of DCLK1 (show DCLK1 Antibodies), POU2F3 (show POU2F3 Antibodies), ALDH1A1 (show ALDH1A1 Antibodies), and IL17RC (show IL17RC Antibodies).

  8. The reaction of IL-17A in the acute lung injury induced by LPS (show TLR4 Antibodies) is stronger than that by PQ.

  9. IL17A promoted osteoblast differentiation and calcification in a partly AKT2dependent manner in MC3T3E1 cells in vitro, possibly reflecting compensation by other signaling pathways. The results of the present study may offer novel perspectives to guide the clinical strategy for the prevention and treatment of periodontitis

  10. Mechanistically, CREB (show CREB1 Antibodies), activated by CD3 (show CD3E Antibodies)-PKC (show PKC Antibodies)- signaling, plays a key role in regulating Th17 cell differentiation, at least in part through directly binding to the Il17-Il17f gene locus.

Cow (Bovine) Interleukin 17A (IL17A) interaction partners

  1. These results support previous gene transcription studies and extend the observation of increased IL-22 (show IL22 Antibodies) and IL-17A responses in M. bovis-infected animals to the level of protein production.

  2. calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.

  3. Data show that CD4 (show CD4 Antibodies)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.

  4. IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.

  5. IL-17A and IL-17F (show IL17F Antibodies) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.

  6. The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.

Pig (Porcine) Interleukin 17A (IL17A) interaction partners

  1. At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (show CD8A Antibodies)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.

  2. Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.

  3. conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (show CD3 Antibodies)(+)CD4 (show CD4 Antibodies)(+) and CD3 (show CD3 Antibodies)(+)gammadeltaTCR(+).

  4. Cloning and expression of interleukin-17.

Rhesus Monkey Interleukin 17A (IL17A) interaction partners

  1. Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.

Guinea Pig Interleukin 17A (IL17A) interaction partners

  1. molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.

Rabbit Interleukin 17A (IL17A) interaction partners

  1. one of the interaction sites between IL17A and its receptor IL17RA (show IL17RA Antibodies)

IL17A Antigen Profile

Protein Summary

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Gene names and symbols associated with anti-Interleukin 17A (IL17A) Antibodies

  • interleukin 17A (IL17A) antibody
  • interleukin 17A (Il17a) antibody
  • ChIL-17 antibody
  • CTLA-8 antibody
  • Ctla8 antibody
  • IL-17 antibody
  • IL-17A antibody
  • IL-17F antibody
  • Il17 antibody
  • IL17A antibody

Protein level used designations for anti-Interleukin 17A (IL17A) Antibodies

CTLA-8 , cytotoxic T-lymphocyte-associated antigen 8 , cytotoxic T-lymphocyte-associated protein 8 , interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) , interleukin-17A , interleukin 17 , IL-17A , interleukin 17A , IL-17 , interleukin-17 , Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

GENE ID SPECIES
3605 Homo sapiens
100034142 Equus caballus
16171 Mus musculus
282863 Bos taurus
395111 Gallus gallus
449530 Sus scrofa
472029 Pan troglodytes
481837 Canis lupus familiaris
708123 Macaca mulatta
301289 Rattus norvegicus
100735572 Cavia porcellus
100339322 Oryctolagus cuniculus
100860877 Capra hircus
101103931 Ovis aries
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