Interleukin 23 Proteins (IL23)

The protein encoded by IL23 is a member of the interleukin 1 cytokine family. Additionally we are shipping Interleukin 23 Kits (86) and Interleukin 23 Antibodies (71) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL23 83430 Q9EQ14
IL23 155140 Q91Z84
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Top Interleukin 23 Proteins at

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
HEK-293 Cells Human Un-conjugated 50 μg 2 to 3 Days
Escherichia coli (E. coli) Human His tag 100 μg 15 to 18 Days
Human Cells Human His tag 5 μg 14 to 16 Days
Human Cells Mouse His tag 5 μg 14 to 16 Days
Human Cells Rat His tag 20 μg 14 to 16 Days
Human Cells Marmoset His tag 20 μg 14 to 16 Days
Human Cells Human His tag   50 μg 4 Days
Hi-5 Cells Human Un-conjugated   0.002 mg 2 to 3 Days
Human Cells Human His tag 50 μg 14 to 16 Days
HEK-293 Cells Human DYKDDDDK Tag   10 μg 5 to 8 Days

IL23 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
Rat (Rattus) ,

Human , , ,

More Proteins for Interleukin 23 (IL23) Interaction Partners

Mouse (Murine) Interleukin 23 (IL23) interaction partners

  1. Our study demonstrates that in dendritic cells infected with Lymphocytic choriomeningitis virus, TLR activation with bacterial PAMPs resulted in reduced IL-12 and IL-23 expression compared to non-infected cells.

  2. Blocking the IL-23 cytokine activity decreased liver cancer development in murine model.

  3. Our work uncovers the IL-23-IL-22 signaling as a regulator of atherosclerosis that restrains expansion of pro-atherogenic microbiota and argues for informed use of cytokine blockers to avoid cardiovascular side effects driven by microbiota and inflammation.

  4. IL-23p19 is a key cytokine responsible for induction of Leishmania-specific Th17 cells that play an important role for progressive disease in susceptible BALB/c mice

  5. these findings show a feed-forward mechanism involving STAT4 and T-BET that modulates the outcome of IL-23 signaling in innate lymphoid cells

  6. IL-23 secreted by myeloid-derived suppressor cells (MDSCs) can activate the androgen receptor pathway in prostate tumour cells, promoting cell survival and proliferation in androgen-deprived conditions; results reveal that MDSCs promote castration-resistant prostate cancer by acting in a non-cell autonomous manner; treatments that block IL-23 can oppose MDSC-mediated resistance to castration in prostate cancer

  7. It has been shown in a genetic psoriasis model that N-WASP controls IL-23 expression in keratinocytes by regulating the degradation of the histone methyltransferases G9a and GLP, and H3K9 dimethylation of the IL-23 promoter.

  8. JunB has an essential role in IL-23-dependent pathogenicity of Th17 cells

  9. HO-1 enhanced STAT3 phosphorylation, which enriched to Il12b and Il23a loci and negatively regulated their transcription. These findings demonstrate the underlying mechanism through which a nutritional can interfere with the immune response. CUR silences IL-23/Th17-mediated pathology by enhancing HO-1/STAT3 interaction in dendritic cells.

  10. This study defines a critical IL-36/IL-23/IL-22 cytokine network instrumental for antimicrobial peptide production and host defense in intestinal mucosa damage using a mouse inflammatory bowel disease model.

  11. IL-23 drives differentiation of peripheral gamma-delta 17 T cells from adult bone marrow-derived precursors.

  12. In mice on a C57BL/6 background, neither IL-23p19 nor IL-17A plays a role for immune protection against L. major in the physiological context of natural infections.

  13. The hormone levels are significantly reduced and lymphocytic infiltration in the lacrimal gland in ovariectomized mice, whereas the frequency of Th17 cells in the blood and spleen and IL-17A and IL-23 expression in the lacrimal glands are increased, leading to reduced tear production and positive fluorescein staining in the cornea.

  14. this study unveiled the role of IL-23-dependent IL-17 induction in LdCen-/- parasite-induced immunity and subsequent protection against visceral leishmaniasis

  15. Results reveal the importance of the IL-23/IL-17 inflammatory axis in secondary brain injury after intracerebral hemorrhage.

  16. RIG-I expression is markedly increased in the affected skin derived from psoriasis patients and from both IL-23- and imiquimod -induced psoriasis-like mouse model.

  17. results show that IL-23 accounts for the main aspects of human and murine lupus including the expansion of double negative T cells, decreased IL-2, and increased IL-17 production

  18. this study shows that IL-23 but not IL-1 contributes to the IL-17A expression induced by subacute O3 exposure

  19. IL-23 released by keratinocytes in response to endogenous TLR4 ligands causes skin DCs, which selectively express IL-23R, to up-regulate their endogenous IL-23 production and drive an IL-22 response in naive CD4(+) T cells that mediates epidermal thickening.

  20. In mice overexpressing IL23, enthesis-resident gamma/delta T cells accumulate in the enthesis, ciliary body, and aortic valve.

Pig (Porcine) Interleukin 23 (IL23) interaction partners

  1. These results provide genetic information about both swine IL-23 the IL-23 receptor alpha (IL-23Ralpha) and IL-12 receptor beta1 (IL-12Rbeta1), which allows for better understanding of interleukin systems involved in pig immunity.

Interleukin 23 (IL23) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene names and symbols associated with Interleukin 23 Proteins (IL23)

  • interleukin 23, alpha subunit p19 (Il23a)
  • interleukin 23 subunit alpha (Il23a)
  • interleukin 23 subunit alpha (IL23A)
  • IL-23 protein
  • il23p19 protein
  • p19 protein
  • SGRF protein

Protein level used designations for Interleukin 23 Proteins (IL23)

IL-23 subunit alpha , IL-23-A , IL-23p19 , interleukin-23 subunit alpha , interleukin-23 subunit p19 , IL-23 p19 subunit , Interleukin-23 p19 subunit , interleukin 23 p19 subunit

83430 Mus musculus
155140 Rattus norvegicus
100135557 Cavia porcellus
100155546 Sus scrofa
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