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IL28A encodes a cytokine distantly related to type I interferons and the IL-10 family. Additionally we are shipping Interleukin 28A (Interferon, lambda 2) Antibodies (101) and Interleukin 28A (Interferon, lambda 2) Proteins (24) and many more products for this protein.
Showing 5 out of 39 products:
Mouse (Murine) IL28A ELISA Kit for Sandwich ELISA - ABIN625145
Cui, Clark, Liu, Xu, Guo, Hu: Viral DNA-Dependent Induction of Innate Immune Response to Hepatitis B Virus in Immortalized Mouse Hepatocytes. in Journal of virology 2015
Show all 2 Pubmed References
Human IL28A ELISA Kit for Sandwich ELISA - ABIN365217
Shaker, Sadik: Polymorphisms in interleukin-10 and interleukin-28B genes in Egyptian patients with chronic hepatitis C virus genotype 4 and their effect on the response to pegylated interferon/ribavirin-therapy. in Journal of gastroenterology and hepatology 2012
IL28 controls proliferation of IECs in mice with colitis and accelerates mucosal healing by activating STAT1 (show STAT1 ELISA Kits).
IL-28A is capable of exacerbating a T-cell-mediated autoimmune disease.
Data indicate that rotavirus infection induces production of interferon (show IFNA ELISA Kits)-lambda (IFN-lambda) and interleukin 22 (IL-22 (show IL22 ELISA Kits)) by intestinal epithelial cells.
IL-28A exerts its antiinflammatory effect by restricting recruitment of IL-1b (show IL1B ELISA Kits)-expressing neutrophils
The level of IFN-lambda2 was significantly increased in the infected cells treated with with shRNAs against influenza a virus M1.
IFN-lambda2 limits VSV replication in the mouse lung.
Data indicate that IPS-1 (show ISYNA1 ELISA Kits)-dependent pathway plays a crucial role in type III IFN production by CD8 (show CD8A ELISA Kits)(+) dendritic cells (DCs) and hepatocytes in response to hepatitis C virus (HCV), leading to cytoplasmic antiviral protein expressions.
NS of severe fever with thrombocytopenia syndrome virus inhibited the activity of IFN-alpha1 (show IFNA1 ELISA Kits), IFN-beta (show IFNB1 ELISA Kits), IFN-lambda1 and IFN-lambda2 through inhibition of STAT1 (show STAT1 ELISA Kits) phosphorylation.
Studies indicate that the type III interferons (IFNs) or IFN-lambdas consists of four members: IFN-lambda1 (IL-29 (show IL29 ELISA Kits)), IFN-lambda2 (IL28A), IFN-lambda3 (IL-28B (show IL28B ELISA Kits)) and IFN-lambda4.
Results showed no association between genotypes and alleles of IL28A, IL28B (show IL28B ELISA Kits) or IL29 (show IL29 ELISA Kits) polymorphisms and Hepatitis C virus infection.
this study provides evidence for potential IL-28A participation in Behcet's diseaseand its value as a therapeutic agent.
Interferon (show IFNA ELISA Kits) regulatory factor (IRF)-3 (show IRF3 ELISA Kits) and -7 are the key transcriptional factors for the induction of IL-28A and IL-28B (show IL28B ELISA Kits) genes, whereas NF-kappaB (show NFKB1 ELISA Kits) is an additional requirement for the induction of the IL-29 (show IL29 ELISA Kits) gene.
The results show that IL-28A/IL-28AR1 dyad-induced wound healing migration requires NF-kappaB (show NFKB1 ELISA Kits)-mediated MMP-9 (show MMP9 ELISA Kits) expression by MAPK (show MAPK1 ELISA Kits) activation.
IL-28 genotype was not associated with response to interferon (show IFNA ELISA Kits) treatment (OR for GT/GG vs. TT, 0.881 (95%CI 0.388 - 2.002); P = 0.762; OR for CT/CC vs. TT, 0.902 (95%CI 0.458 - 1.778); P = 0.766).
p38 MAPK (show MAPK14 ELISA Kits) pathway mediates IL-28A-induced cell migration through MMP-9 (show MMP9 ELISA Kits) expression by activating NF-kappaB (show NFKB1 ELISA Kits) and AP-1 (show FOSB ELISA Kits) binding motifs.
Elevated expression of inflammatory cytokines (IL-5 (show IL5 ELISA Kits), IL-20 (show IL20 ELISA Kits), and IL-28A) is associated with bladder cancer development.
Plasmacytoid dendritic cells are major producers of IFN-lambda2 (a type III interferon (show IFNA ELISA Kits)) in response to viral stimulation.
Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
, interferon lambda-2
, interleukin 28A
, cytokine Zcyto20
, interferon lambda 2
, interferon-lambda 2
, interleukin 28A (interferon, lambda 2)