Inverted Formin, FH2 and WH2 Domain Containing (INF2) ELISA Kits

INF2 represents a member of the formin family of proteins. Additionally we are shipping INF2 Antibodies (44) and INF2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
INF2 64423 Q27J81
INF2 70435 Q0GNC1
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Top INF2 ELISA Kits at antibodies-online.com

Showing 2 out of 4 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests 11 to 18 Days
$838.60
Details
Mouse < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Details

More ELISA Kits for INF2 Interaction Partners

Human Inverted Formin, FH2 and WH2 Domain Containing (INF2) interaction partners

  1. INF2 is a novel pro-apoptotic inducer of oxidative injury in epidermal cells.

  2. INF2 seems to be not only the cause of FSGS, but also of ESRD of unknown etiology.

  3. INF2-mediated actin polymerization on the endoplasmic reticulum stimulates mitochondrial division by two independent mechanisms: (1) mitochondrial calcium uptake, leading to inner mitochondrial membrane constriction; and (2) Drp1 oligomerization, leading to outer mitochondrial membrane constriction.

  4. Studies indicate that INF2, a formin, that is mutated in hereditary renal and neurodegenerative disorders.

  5. Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ alpha-1) and profilin 2.

  6. hese findings reveal novel molecular events underlying the regulation of INF2 function and localization, and provided insights in understanding the relationship between SPOP mutations and dysregulation of mitochondrial dynamics in prostate cancer.

  7. All individuals with INF2 mutations presenting with a thrombotic microangiopathy also had atypical hemolytic uremic syndrome risk haplotypes, potentially accounting for the genetic pleiotropy

  8. Propose that examination of INF2 expression may help to differentiate minimal change disease from focal segmental glomerulosclerosis and evaluate the clinical severity of steroid resistance nephrotic syndrome in children.

  9. FHOD1 and INF2 are novel regulators of inter- and intra-structural contractility of podosomes.

  10. The authors propose Spire1C isoform cooperates with INF2 to regulate actin assembly at endoplasmic reticulum-mitochondrial contacts.

  11. Report novel mutations in the inverted formin 2 gene of Chinese families contributing to focal segmental glomerulosclerosis.

  12. Assembly and turnover of short actin filaments by the formin INF2 and profilin.

  13. INF2 mutations are associated with focal segmental glomerulosclerosis.

  14. this study identifed three novel mutations of INF likely efect hereditary neuropathy with glomerulopathy.

  15. actin monomer binding to the DAD of INF2 competes with the DID/DAD interaction, thereby activating actin polymerization

  16. INF2 mutation was detected both father and his son

  17. This study showed that INF2 mutations in Charcot-Marie-Tooth disease complicated with focal segmental glomerulosclerosis.

  18. In podocytes, INF2 appears to be an important modulator of actin-dependent behaviors that are under the control of Rho/mDia signaling.

  19. INF2 mutations were found in 2 of 281 individuals with sporadicfocal and segmental glomerulosclerosis

  20. Our study confirms the link between INF2 mutations and Charcot-Marie-Tooth-associated glomerulopathy and widens the spectrum of pathogenic mutations.

Mouse (Murine) Inverted Formin, FH2 and WH2 Domain Containing (INF2) interaction partners

  1. we purified an INF2 inhibitor from mouse brain tissue, and identified it as a complex of lysine-acetylated actin (KAc-actin) and cyclase-associated protein (CAP). Inhibition of INF2 by CAP-KAc-actin is dependent on the INF2 diaphanous inhibitory domain (DID).

  2. the pathogenesis of cerebral ischemia-reperfusion injury is associated with Nurr1 upregulation followed by augmented mitochondrial fission via an abnormal YAP-INF2 pathways

  3. These data support a critical regulatory role for INF2 in trophoblast invasion-a necessary process for placentation.

  4. In mice, normal INF2 function is not required for glomerular development but normal INF2 is required for regulation of the actin-based behaviors necessary for response to and/or recovery from injury.

  5. Data highlight a unique mechanism of formin action in which mDia1 and INF2 function in series to stabilize MTs and point to IQGAP1 as a scaffold that facilitates the activation of one formin by another.

  6. The perinuclear actin rim structure colocalized with INF2 on stimulation, and INF2 depletion resulted in attenuation of the rim formation.

  7. Splice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture.

  8. Data suggest a role for INF1 in microtubule modification and potentially in coordinating microtubule and F-actin structure.

INF2 Antigen Profile

Antigen Summary

This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.

Gene names and symbols associated with INF2

  • inverted formin, FH2 and WH2 domain containing (INF2) antibody
  • inverted formin, FH2 and WH2 domain containing (Inf2) antibody
  • 2610204M08Rik antibody
  • AA589465 antibody
  • AW125550 antibody
  • C14orf151 antibody
  • C14orf173 antibody
  • CMTDIE antibody
  • EG629699 antibody
  • FSGS5 antibody
  • pp9484 antibody

Protein level used designations for INF2

HBEAG-binding protein 2 binding protein C , HBEBP2-binding protein C , inverted formin-2 , formin, inverted

GENE ID SPECIES
64423 Homo sapiens
70435 Mus musculus
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