Inverted Formin, FH2 and WH2 Domain Containing (INF2) ELISA Kits

INF2 represents a member of the formin family of proteins.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human INF2 INF2 64423 Q27J81
Anti-Mouse INF2 INF2 70435 Q0GNC1
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days
Mouse < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days

More ELISA Kits for INF2 Interaction Partners

Human Inverted Formin, FH2 and WH2 Domain Containing (INF2) interaction partners

  1. Disease causing mutations in inverted formin 2 regulate its binding to G-actin (show ACTB ELISA Kits), F-actin capping protein (CapZ (show CAPZB ELISA Kits) alpha-1) and profilin 2 (show PFN2 ELISA Kits).

  2. hese findings reveal novel molecular events underlying the regulation of INF2 function and localization, and provided insights in understanding the relationship between SPOP (show SPOP ELISA Kits) mutations and dysregulation of mitochondrial dynamics in prostate cancer.

  3. All individuals with INF2 mutations presenting with a thrombotic microangiopathy also had atypical hemolytic uremic syndrome risk haplotypes, potentially accounting for the genetic pleiotropy

  4. Propose that examination of INF2 expression may help to differentiate minimal change disease from focal segmental glomerulosclerosis and evaluate the clinical severity of steroid resistance nephrotic syndrome in children.

  5. FHOD1 (show FHOD1 ELISA Kits) and INF2 are novel regulators of inter- and intra-structural contractility of podosomes.

  6. The authors propose Spire1C isoform cooperates with INF2 to regulate actin assembly at endoplasmic reticulum-mitochondrial contacts.

  7. Report novel mutations in the inverted formin 2 gene of Chinese families contributing to focal segmental glomerulosclerosis.

  8. Assembly and turnover of short actin filaments by the formin (show FMN1 ELISA Kits) INF2 and profilin (show PFN1 ELISA Kits).

  9. INF2 mutations are associated with focal segmental glomerulosclerosis.

  10. this study identifed three novel mutations of INF (show GIF ELISA Kits) likely efect hereditary neuropathy with glomerulopathy.

Mouse (Murine) Inverted Formin, FH2 and WH2 Domain Containing (INF2) interaction partners

  1. In mice, normal INF2 function is not required for glomerular development but normal INF2 is required for regulation of the actin-based behaviors necessary for response to and/or recovery from injury.

  2. Data highlight a unique mechanism of formin (show FMN1 ELISA Kits) action in which mDia1 and INF2 function in series to stabilize MTs (show NEU2 ELISA Kits) and point to IQGAP1 (show IQGAP1 ELISA Kits) as a scaffold that facilitates the activation of one formin (show FMN1 ELISA Kits) by another.

  3. The perinuclear actin rim structure colocalized with INF2 on stimulation, and INF2 depletion resulted in attenuation of the rim formation.

  4. Splice variant-specific cellular function of the formin (show FMN1 ELISA Kits) INF2 in maintenance of Golgi architecture.

  5. Data suggest a role for INF1 in microtubule modification and potentially in coordinating microtubule and F-actin structure.

INF2 Antigen Profile

Antigen Summary

This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.

Gene names and symbols associated with INF2

  • inverted formin, FH2 and WH2 domain containing (INF2) antibody
  • inverted formin, FH2 and WH2 domain containing (Inf2) antibody
  • 2610204M08Rik antibody
  • AA589465 antibody
  • AW125550 antibody
  • C14orf151 antibody
  • C14orf173 antibody
  • CMTDIE antibody
  • EG629699 antibody
  • FSGS5 antibody
  • pp9484 antibody

Protein level used designations for INF2

HBEAG-binding protein 2 binding protein C , HBEBP2-binding protein C , inverted formin-2 , formin, inverted

64423 Homo sapiens
70435 Mus musculus
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