anti-K(lysine) Acetyltransferase 8 (KAT8) Antibodies

KAT8 encodes a member of the MYST histone acetylase protein family. Additionally we are shipping K(lysine) Acetyltransferase 8 Kits (9) and K(lysine) Acetyltransferase 8 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KAT8 310194 Q5XI06
KAT8 84148 Q9H7Z6
KAT8 67773 Q9D1P2
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Top anti-K(lysine) Acetyltransferase 8 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MYST1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP, WB Immunocytochemistry/Immunofluorescence: MYST1 Antibody  - The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red). Previous Immunohistochemistry: MYST1 Antibody  - FFPE section of human ovarian carcinoma. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MYST1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$335.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-HMOF/MYST1(C-term) Pab (ABIN387971) in K562 cell line lysates (35 µg/lane). HMOF/MYST1(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with HMOF/MYST1 antibody (C-term) (ABIN387971), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, ICC, IHC, WB Figure 1: Western blot analysis using MYST1 mouse mAb against Hela (1), HepG2 (2) and SMMC-7721 (3) cell lysate. Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), normal esophagus epithelium (B), rectum adenocarcinoma (C), lung squamous cell carcinoma (D), breast infiltrating carcinoma (E), and breast infiltrating carcinoma (F) tissues, showing nuclear localization using MOF/MYST1 mouse mAb with DAB staining. Dilution: 1/200 - 1/1000 100 μL Log in to see 10 to 11 Days
$475.29
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL Log in to see 7 to 9 Days
$484.00
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, IF/ICC, IHC, WB 100 μL Log in to see 11 to 16 Days
$426.40
Details

Top referenced anti-K(lysine) Acetyltransferase 8 Antibodies

  1. Human Monoclonal KAT8 Primary Antibody for ICC, IHC - ABIN1724671 : Neal, Pannuti, Smith, Lucchesi: A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF. in Biochimica et biophysica acta 2000 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal KAT8 Primary Antibody for IP, WB - ABIN5665730 : Li, Corsa, Pan, Wu, Ferguson, Yu, Min, Dou: MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1. in Molecular and cellular biology 2010 (PubMed)
    Show all 3 Pubmed References

More Antibodies against K(lysine) Acetyltransferase 8 Interaction Partners

Human K(lysine) Acetyltransferase 8 (KAT8) interaction partners

  1. Data describe a trans-histone modification pathway involving PKN1 (show PKN1 Antibodies)/histone H3 (show HIST3H3 Antibodies) threonine 11 phosphorylation followed by WDR5 (show WDR5 Antibodies)/MLL (show MLL Antibodies) histone methyltransferase and KAT8/histone acetyltransferase (show HAT Antibodies) recruitment to effect androgen-dependent gene activation and prostate cancer cell proliferation.

  2. These findings provide insight into the regulation of LSD1 (show KDM1A Antibodies) and Epithelial-to-Mesenchymal Transition (EMT (show ITK Antibodies)) and identify MOF as a critical suppressor of EMT (show ITK Antibodies) and tumor progression.

  3. This work identifies MOF as a key regulator of cellular stress response in glomerular podocytes.

  4. recent results indicate MOF is an upstream regulator of the ATM (ataxia-telangiectasia mutated (show ATM Antibodies)) protein, the loss of which is responsible for ataxia telangiectasia (AT). ATM (show ATM Antibodies) is a key regulatory kinase that interacts with and phosphorylates multiple substrates that influence critical, cell-cycle control and DNA damage repair pathways in addition to other pathways.

  5. Histone acetyltransferase (show HAT Antibodies) activity of MOF is required to sustain MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies) leukemia and may be important for multiple AML (show RUNX1 Antibodies) subtypes.

  6. our findings reveal that TET1 (show TET1 Antibodies) forms a complex with hMOF to modulate its function and the level of H4K16Ac ultimately affect gene expression and DNA repair.

  7. these studies point to the critical and specific role of hMOF Lys (show LYZ Antibodies)-274 autoacetylation in hMOF stability and cognate substrate acetylation and argues that binding of Ac-CoA to hMOF likely drives Lys (show LYZ Antibodies)-274 autoacetylation for subsequent cognate substrate acetylation.

  8. MOF is a dual-transcriptional regulator of nuclear and mitochondrial genomes connecting epigenetics and metabolism.

  9. MOF is highly enriched in induced pluripotent stem cells (iPSCs), and MOF expression is upregulated during the reprogramming process. The ectopic expression of MOF promotes reprogramming. MOF affects Wdr5 (show WDR5 Antibodies) and endogenous Oct4 (show POU5F1 Antibodies) expression.

  10. Along with the PHF20 (show PHF20 Antibodies)/MOF complex, G9a (show EHMT2 Antibodies) links the crosstalk between ERalpha (show ESR1 Antibodies) methylation and histone acetylation that governs the epigenetic regulation of hormonal gene expression.

Mouse (Murine) K(lysine) Acetyltransferase 8 (KAT8) interaction partners

  1. MOF regulates male meiosis and is involved in the expansion of all three waves of H2AX phosphorylation from the leptotene to pachytene stages, initiated by ATM and ATR, respectively.

  2. study demonstrated that HAT (show HAT Antibodies) Mof is involved in the development of colitis, and the lack of Mof ameliorates DSS (show PMP22 Antibodies)-induced colitis in mice.

  3. This work identifies MOF as a key regulator of cellular stress response in glomerular podocytes.

  4. demonstrate that KAT8 is essential for female fertility by regulating antioxidant gene expression and identify KAT8 as the first histone acetyltransferase (show HAT Antibodies) with an essential function in oogenesis

  5. MOF is a developmental-stage-specific chromatin regulator found to be essential for adult but not early fetal hematopoiesis.

  6. MOF is a dual-transcriptional regulator of nuclear and mitochondrial genomes connecting epigenetics and metabolism.

  7. STAT5B (show STAT5B Antibodies) and MOF work as negative regulators in adipogenesis.

  8. NSL and MSL HAT (show HAT Antibodies) complexes differentially regulate specific sets of expressed genes in mESCs and during differentiation

  9. cardiac-specific MOF overexpression protected mice from transverse aortic constriction-induced cardiac hypertrophy, with reduced radios of heart weight/body weight, decreased left ventricular wall thickness and increased fractional shortening.

  10. Mof plays a critical role in T-cell differentiation and that depletion of Mof in T cells reduces T-cell numbers and, by an undefined mechanism, induces genomic instability in B cells through bystander mechanism.

K(lysine) Acetyltransferase 8 (KAT8) Antigen Profile

Protein Summary

This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KAT8

  • K(lysine) acetyltransferase 8 (kat8) antibody
  • lysine acetyltransferase 8 (KAT8) antibody
  • lysine acetyltransferase 8 (Kat8) antibody
  • K(lysine) acetyltransferase 8 (Kat8) antibody
  • 2010203C02Rik antibody
  • 5830450F21Rik antibody
  • D7Ertd629e antibody
  • hMOF antibody
  • MOF antibody
  • MYST1 antibody
  • wu:fb22g02 antibody
  • wu:fj22d09 antibody
  • ZC2HC8 antibody
  • zgc:66387 antibody

Protein level used designations for KAT8

MYST histone acetyltransferase 1 , histone acetyltransferase KAT8 , K(lysine) acetyltransferase 8 , probable histone acetyltransferase MYST1-like , MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1 , MYST protein 1 , MYST-1 , lysine acetyltransferase 8 , probable histone acetyltransferase MYST1 , histone acetyltransferase MYST1 , ortholog of Drosophila males absent on the first (MOF) , histone acetyltransferase Myst1

GENE ID SPECIES
548988 Xenopus (Silurana) tropicalis
100003790 Danio rerio
100019305 Monodelphis domestica
100064910 Equus caballus
100341732 Oryctolagus cuniculus
100387289 Callithrix jacchus
100435717 Pongo abelii
100522367 Sus scrofa
100593658 Nomascus leucogenys
310194 Rattus norvegicus
84148 Homo sapiens
67773 Mus musculus
479777 Canis lupus familiaris
100125883 Bos taurus
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