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MYST1 Products

(K(lysine) Acetyltransferase 8 (KAT8))

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This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

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Featured MYST1 Categories

MYST1 Antibodies

High quality antibodies with extensive validation data.

MYST1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MYST1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MYST1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC
Validations
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  • (3)
Cat. No. ABIN1724671
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN543311
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7268063
Quantity 100 μL
Datasheet Datasheet

Recommended MYST1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968087
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN5594634
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228830
Quantity 96 tests
Datasheet Datasheet

Recommended MYST1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311867
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3082270
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3128900
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MYST1 products

Jiang, Gao, Zheng, Yin, Wang, Zhong, Ali, Khan, Hao, Fang, Sun, Xu, Pandita, Jiang, Shi: "MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice." in: PLoS genetics, Vol. 14, Issue 5, pp. e1007300, (2018) (PubMed).

Badeaux, Yang, Cardenas, Vemulapalli, Chen, Kusewitt, Richie, Li, Bedford: "Loss of the methyl lysine effector protein PHF20 impacts the expression of genes regulated by the lysine acetyltransferase MOF." in: The Journal of biological chemistry, Vol. 287, Issue 1, pp. 429-37, (2012) (PubMed).

Lu, Li, Lv, Wu, Liu, Liang: "Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin." in: Cell research, Vol. 21, Issue 8, pp. 1182-95, (2011) (PubMed).

Li, Corsa, Pan, Wu, Ferguson, Yu, Min, Dou: "MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1." in: Molecular and cellular biology, Vol. 30, Issue 22, pp. 5335-47, (2010) (PubMed).

Pfister, Rea, Taipale, Mendrzyk, Straub, Ittrich, Thuerigen, Sinn, Akhtar, Lichter: "The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 6, pp. 1207-13, (2008) (PubMed).

Rea, Xouri, Akhtar: "Males absent on the first (MOF): from flies to humans." in: Oncogene, Vol. 26, Issue 37, pp. 5385-94, (2007) (PubMed).

Gupta, Guerin-Peyrou, Sharma, Park, Agarwal, Ganju, Pandita, Choi, Sukumar, Pandita, Ludwig, Pandita: "The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis." in: Molecular and cellular biology, Vol. 28, Issue 1, pp. 397-409, (2007) (PubMed).

Akhtar, Becker: "The histone H4 acetyltransferase MOF uses a C2HC zinc finger for substrate recognition." in: EMBO reports, Vol. 2, Issue 2, pp. 113-8, (2001) (PubMed).

Neal, Pannuti, Smith, Lucchesi: "A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF." in: Biochimica et biophysica acta, Vol. 1490, Issue 1-2, pp. 170-4, (2000) (PubMed).

Sterner, Berger: "Acetylation of histones and transcription-related factors." in: Microbiology and molecular biology reviews : MMBR, Vol. 64, Issue 2, pp. 435-59, (2000) (PubMed).

Synonyms and alternative names related to MYST1

K(lysine) acetyltransferase 8 (kat8), lysine acetyltransferase 8 (KAT8), lysine acetyltransferase 8 (Kat8), K(lysine) acetyltransferase 8 (Kat8), 2010203C02Rik, 5830450F21Rik, D7Ertd629e, hMOF, MOF, myst1, Myst1, MYST1, wu:fb22g02, wu:fj22d09, ZC2HC8, zgc:66387

Protein level used designations for MYST1

  • MYST histone acetyltransferase 1
  • histone acetyltransferase KAT8
  • K(lysine) acetyltransferase 8
  • probable histone acetyltransferase MYST1-like
  • MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1
  • MYST protein 1
  • MYST-1
  • lysine acetyltransferase 8
  • probable histone acetyltransferase MYST1
  • histone acetyltransferase MYST1
  • ortholog of Drosophila males absent on the first (MOF)
  • histone acetyltransferase Myst1
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