anti-K14 Protein (TVAG_247310) Antibodies

TVAG_247310 encodes a member of the keratin family, the most diverse group of intermediate filaments.

list all antibodies Gene Name GeneID UniProt
TVAG_247310 3861 P02533
TVAG_247310 16664 Q61781
TVAG_247310 287701 Q6IFV1
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Top anti-K14 Protein Antibodies at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 750 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
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Human Rabbit Alexa Fluor 680 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

More Antibodies against K14 Protein Interaction Partners

Human K14 Protein (TVAG_247310) interaction partners

  1. Efficient homology-directed repair of a dominant negative KRT14 (show KRT14 Antibodies) mutation via CRISPR/Cas9 nickases in epidermolysis bullosa simplex patients' keratinocytes has been reported.

  2. Immunocytochemical staining using cocktail antibody targeting p63 (show RPE65 Antibodies)/CK14 (show KRT14 Antibodies) was useful for the differential diagnosis of FA and DCIS in FNAC of the breast.

  3. the findings show that squamous and micropapillary bladder cancers have different expression patterns of CK14 (show KRT14 Antibodies) and FOXA1 (show FOXA1 Antibodies) and suggest that they arise from distinct precursors.

  4. PADI4 (show PADI4 Antibodies) contributes to gastric tumorigenesis by upregulating CXCR2 (show CXCR2 Antibodies), KRT14 (show KRT14 Antibodies) and TNF-alpha (show TNF Antibodies) expression.

  5. this study adds a further 10 novel mutations to the catalogued genotype-phenotype correlations in epidermolysis bullosa simplex and demonstrates a potential modifying effect of SNPs on the phenotype. We therefore support the notion of full DNA sequencing of both KRT5 (show KRT5 Antibodies) and KRT14 (show KRT14 Antibodies) genes so as to not miss any variants in the genes contributing to the phenotype.

  6. The novel c.1234A>G(p.Ile412Val) mutation of the KRT14 (show KRT14 Antibodies) gene is probably responsible for the disease.

  7. Keratin14/p63 (show RPE65 Antibodies)-positive epithelial proliferations suggest benign breast disease.

  8. K14 (show KRT14 Antibodies) was coexpressed with alphav-integrin (show ITGAV Antibodies) in fetal and adult corneas and cultured corneolimbal epithelium, and colony-forming efficiency (an indicator of stem cell activity) was similar in cells from both sources.

  9. Loss of keratin 14 (show KRT14 Antibodies) is associated with epidermolysis bullosa.

  10. vimentin (show VIM Antibodies) regulates the differentiation switch via modulation of K5/K14 (show KRT14 Antibodies) expression. Moreover, because there was a significant correlation between high vimentin (show VIM Antibodies)-K14 (show KRT14 Antibodies) expression and recurrence/poor survival in oral cancer patients, vimentin (show VIM Antibodies)-K14 (show KRT14 Antibodies) together may prove to be the novel markers for the prognostication of human oral cancer.

Mouse (Murine) K14 Protein (TVAG_247310) interaction partners

  1. KRT14 (show KRT14 Antibodies) is expressed in a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis.

  2. CDK1 (show CDK1 Antibodies), Aurora-B (show AURKC Antibodies), and Rho-kinase (show ROCK2 Antibodies) phosphorylate keratin 5 (show KRT36 Antibodies)/14.

  3. RA regulates Krt5 (show KRT5 Antibodies) and Krt14 (show KRT14 Antibodies) expression independently of stem cell character in developing salivary epithelium. The stem cell gene Kit is regulated inversely from Krt5 (show KRT5 Antibodies)/Krt14 (show KRT14 Antibodies) by RA signaling.

  4. Analysis of K14 variants with single or multiple substitutions of cysteine residues points to a spatial and temporal hierarchy in how Cys-4/Cys-40 and Cys-367 regulate keratin assembly in vitro and filament dynamics in live keratinocytes

  5. Disulfide bonding is a novel and important mechanism regulating the assembly, intracellular organization, and dynamics of K14 (show KRT14 Antibodies)-containing intermediate filaments in skin keratinocytes.

  6. K14 (show KRT14 Antibodies)-VEGF (show VEGFA Antibodies) transgenic mouse a valuable model to study novel immunotherapies for psoriasis

  7. autoantibodies in Scurfy (show FOXP3 Antibodies) mice and patients with IPEX (show FOXP3 Antibodies) target keratin 14 (show KRT14 Antibodies)

  8. nipple connective tissue and its development: insights from the keratin 14-PTHrP mouse

  9. The keratin-14 (show KRT14 Antibodies) IL-4 (show IL4 Antibodies) transgenic (Tg) mouse model of atopic dermatitis (AD) is characterized by skin infiltration of T cells, early up-regulation of T(h)2 cytokines and late surge of T(h)1 cytokines.

  10. These studies provide a potential mechanism by which deltaNp63 directly governs the expression of K14 (show KRT14 Antibodies) in a keratinocyte-specific manner.

K14 Protein (TVAG_247310) Antigen Profile

Protein Summary

This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.

Gene names and symbols associated with TVAG_247310

  • keratin 14 (KRT14) antibody
  • keratin 14 (Krt14) antibody
  • AI626930 antibody
  • CK14 antibody
  • EBS3 antibody
  • EBS4 antibody
  • K14 antibody
  • Ka14 antibody
  • Krt-1.14 antibody
  • Krt1-14 antibody
  • NFJ antibody

Protein level used designations for TVAG_247310

CK-14 , cytokeratin 14 , cytokeratin-14 , keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) , keratin, type I cytoskeletal 14 , keratin-14 , epidermolysis bullosa simplex, Dowling-Meara, Koebner , keratin complex 1, acidic, gene 14 , K14 , type I keratin Ka14

GENE ID SPECIES
3861 Homo sapiens
16664 Mus musculus
287701 Rattus norvegicus
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