anti-KIN, Antigenic Determinant of RecA Protein Homolog (Mouse) (KIN) Antibodies

The protein encoded by KIN is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Additionally we are shipping KIN Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KIN 16588 Q8K339
KIN 689197  
KIN 22944 O60870
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Top anti-KIN Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Human kidney Human Spermatophore 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-KIN Antibody Titration:  2.5ug/ml  Positive Control:  Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- KIN Picoband antibody, IHC(P) IHC(P): Human Oesophagus Squama Cancer Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Cow Rabbit Un-conjugated WB 100 μg Log in to see 11 to 14 Days
$493.17
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB Anti-KIN antibody, Western blotting Lane 1: Rat Skeletal Muscle Tissue Lysate Lane 2: Human Placenta Tissue Lysate Lane 3: Rat Testis Tissue Lysate 100 μg Log in to see 4 to 6 Days
$240.00
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$446.88
Details
Bat Rabbit Un-conjugated WB   100 μg Log in to see 11 to 14 Days
$463.83
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human kidney and (B) human spermatophore tissues with KIN polyclonal antibody . Western blot analysis of HepG2 cell lysate with KIN polyclonal antibody . 100 μL Log in to see 11 to 12 Days
$452.00
Details

More Antibodies against KIN Interaction Partners

Mouse (Murine) KIN, Antigenic Determinant of RecA Protein Homolog (Mouse) (KIN) interaction partners

  1. This report demonstrates the importance of Kin17 as a critical factor that acts prior to the repair phase of DSB repair and is of bona fide importance for CSR.

  2. identification of KIN17 as a component of the human spliceosome indicate that this protein may participate in RNA processing

Human KIN, Antigenic Determinant of RecA Protein Homolog (Mouse) (KIN) interaction partners

  1. Findings demonstrate that kin17 is closely related to the cell proliferation and invasion of cervical cancer.

  2. overexpression of KIN rendered colorectal cancer cells enriching cancer stem cell (CSC) markers and CSC phenotype, and silencing KIN reduced CSC markers and CSC phenotype.

  3. Trimethylated at Lys-135 by METTL22

  4. up-regulation of kin17 is strongly associated with cellular proliferation, DNA replication, DNA damage response and breast cancer development

  5. ionizing radiation triggers chromatin complex formation in human cells

  6. The overexpression of human kin17 protein in vivo and the introduction of increased amounts of human kin17 protein in an in vitro assay reduced T-antigen-dependent DNA replication.

  7. results indicate the presence of functional XPA and XPC proteins is essential for the up-regulation of the KIN17 gene after UVC irradiation; also show that the integrity of global genome repair is required to trigger KIN17 gene expression

  8. KIN17 protein may be a component of the DNA replication machinery that participates in the cellular response to unrepaired DSBs, and an impaired KIN17 pathway leads to an increased sensitivity to ionizing radiation.

  9. A chromatin-associated protein conserved during evolution and overproduced in certain human tumor cell lines, which is involved in DNA replication.

  10. Kin17 protein strongly associates in vivo with DNA fragments containing replication origins in both human HeLa and monkey CV-1 cells.

  11. C-terminal domain of human KIN17 has a basic pI, heavy-atom derivatives were obtained by soaking crystals with negatively charged ions such as tungstate & iodine. Replacement of LiCl by KI in cryosolution allowed determination of phases from iodide ions.

  12. Analysis of KIN17 structure complexed with tungstate shows structural variability within the domain

  13. Thus, human KIN17 region 51-160 might rather be involved in protein-protein interaction through its conserved surface centered on the 3(10)-helix.

KIN Antigen Profile

Protein Summary

The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with KIN

  • Kin17 DNA and RNA binding protein (Kin) antibody
  • Kin17 DNA and RNA binding protein S homeolog (kin.S) antibody
  • Kin17 DNA and RNA binding protein (KIN) antibody
  • BTCD antibody
  • KIN17 antibody

Protein level used designations for KIN

DNA/RNA-binding protein KIN17 , KIN, antigenic determinant of recA protein homolog , binding to curved DNA , HsKin17 protein

GENE ID SPECIES
16588 Mus musculus
689197 Rattus norvegicus
447303 Xenopus laevis
22944 Homo sapiens
478010 Canis lupus familiaris
519670 Bos taurus
419109 Gallus gallus
Selected quality suppliers for anti-KIN (KIN) Antibodies
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