Keratin 10 Proteins (KRT10)

KRT10 encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Additionally we are shipping Keratin 10 Antibodies (383) and Keratin 10 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KRT10 3858 P13645
KRT10 16661 P02535
KRT10 450225 Q6IFW6
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Top Keratin 10 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$778.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,498.00
Details
Escherichia coli (E. coli) Rat His tag,S tag   100 μg Log in to see 15 to 18 Days
$736.00
Details
Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 11 to 18 Days
$668.03
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$696.46
Details

KRT10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus) ,
,

More Proteins for Keratin 10 (KRT10) Interaction Partners

Human Keratin 10 (KRT10) interaction partners

  1. Results show that missense mutations exert dominant negative effects on the keratins K1/K10 protein structure by altering inter-chain interactions.

  2. KRT10 gene mutation was present in all of the affected individuals, but absent in the five unaffected and 100 ethnically-matched healthy controls.

  3. Mutations in the highly conserved helix initiation motif of K10 were associated with mild or severe form of epidermolytic ichthyosis (show LBR Proteins)

  4. Case Report: post-zygotic mosaicism of KRT/1o mutations in epidermolytic Ichthyosis (show LBR Proteins).

  5. Report genetic/clinical spectrum of KRT10 mutations in keratinopathic ichthyosis (show LBR Proteins).

  6. We present an autosomal dominant pedigree with epidermolytic ichthyosis (show LBR Proteins) resulting from a new heterozygous missense mutation in keratin 10.

  7. Complete structure of an epithelial keratin 1/keratin 10 dimer has been presented.

  8. recombinant adenovirus-mediated overexpression of KRT10 and PTEN may improve the cisplatin resistance of ovarian cancer in vitro and in vivo

  9. findings provide structural insights into phenotypic variation in epidermolytic ichthyosis (show LBR Proteins) due to KRT10 mutations

  10. The diagnosis of ichthyosis (show LBR Proteins) with confetti was confirmed by the identification of 2 previously unreported mutations in intron 6 and exon 7 of KRT10.

Mouse (Murine) Keratin 10 (KRT10) interaction partners

  1. This study demonstrates that the loss of the main cytoskeletal components of plantar epidermis, i.e. K2 and K10, can be only partly compensated by the upregulation of other keratins.

  2. The Krt1(-/-);Krt10(-/-) mice showed premature loss of nuclei during epidermal differentiation and lower levels of emerin (show EMD Proteins), lamin A/C (show LMNA Proteins) and Sun1 (show SUN1 Proteins), revealing a previously unknown function for IFs in maintaining nuclear integrity in the upper epidermis.

  3. Aging enhances susceptibility to pneumococcal pneumonia in a K10-dependent manner.

  4. The epidermis of adult K10-/- mice displayed hyperproliferation of basal keratinocytes and increased cell size,accompanied by the induction of c-Myc (show MYC Proteins), cyclin D1 (show CCND1 Proteins), 14-3-3sigma and wound healing keratins K6 and K16 (show KRT16 Proteins).

  5. loss of a keratin, a cytoskeletal protein (show ADD3 Proteins), reduces tumor formation

  6. The absence of keratin 10 stimulates cell differentiation and proliferation in sebacous glands.

Keratin 10 (KRT10) Protein Profile

Protein Summary

This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.

Gene names and symbols associated with Keratin 10 Proteins (KRT10)

  • keratin 10 (KRT10)
  • keratin 10 (Krt10)
  • keratin 10, type I S homeolog (krt10.S)
  • BCIE protein
  • BIE protein
  • CK10 protein
  • D130054E02Rik protein
  • EHK protein
  • K1C1 protein
  • K10 protein
  • Ka10 protein
  • Ker10 protein
  • KPP protein
  • Krt-1.10 protein
  • Krt1-10 protein

Protein level used designations for Keratin 10 Proteins (KRT10)

CK-10 , cytokeratin 10 , keratin, type I cytoskeletal 10 , keratin-10 , 56 kDa cytokeratin , cytokeratin-10 , epidermal keratin 10 , intermediate filament protein , keratin complex 1, acidic, gene 10 , keratin, type I cytoskeletal 59 kDa , suprabasal cytokeratin 10 , K10 , cytokeratin VIB , cytokeratin-6B , epidermolytic hyperkeratosis; keratosis palmaris et plantaris , keratin 10 (epidermolytic hyperkeratosis) , keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris) , type I keratin KA10 , keratin 25D , epithelial keratin 10 , epithelial keratin-10 , keratin 10

GENE ID SPECIES
3858 Homo sapiens
16661 Mus musculus
281888 Bos taurus
450225 Rattus norvegicus
468240 Pan troglodytes
491006 Canis lupus familiaris
100009029 Oryctolagus cuniculus
100381074 Xenopus laevis
100470629 Ailuropoda melanoleuca
100519971 Sus scrofa
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