Keratin 7 (KRT7) ELISA Kits

Human Keratin 7 (KRT7) interaction partners

1. High Proliferative Placenta-Derived Multipotent Cells Express Cytokeratin 7 at Low Level.

2. FOXA1 promoted proliferation, migration, invasion, and decreased chemosensitivity of gastric cancer cells to 5-Fu treatment through transcriptional activator KRT7

3. CK7 expression is an independent prognostic factor for esophageal squamous cell carcinoma, and FOXA1 is a non-independent prognostic factor.

4. MUC-1, CK7, and c-p27 immunostaining can be used as the predictive markers for esophageal cancer progression from Barrett's esophagus.

5. CK7, unlike p16, is not useful as a prognostic biomarker in cervical intraepithelial neoplasia 2, but is still a useful prognostic marker for cervical intraepithelial neoplasia 1.

6. Data indicate that de novo expression of KRT7 and KRT19 resulting in altered plasticity and stem cell characteristics of epithelial cells might be a crucial factor in increasing the risk of tumor development in end-stage kidneys.

7. High expression of CK-7 is associated with intrahepatic cholangiocarcinoma.

8. Positive expression of CK7 associated with pathological features of lymph node metastasis and T stage may be independent clinical parameters for poor prognosis of patients with lung cancer.

9. Research show that circulating CK7 mRNA positive cells were found in patients with bladder urothelial cancer of varying stages, and the detection rates increased with stage predicting worse clinical scenario.

10. CK7/ HPV-L1 expression, and the presence of koilocytosis can be used for prognostication in patients with cervical low-grade squamous intraepithelial lesions.

11. KRT7-AS formed an RNA-RNA hybrid with KRT7 and controlled KRT7 expression at both the mRNA and the post-transcriptional levels. forced overexpression of the KRT7-overlapping region (OL) of KRT7-AS (but not its non-KRT7-OL portions) increased keratin 7 protein levels in cells. Finally, forced overexpression of full-length KRT7-AS or OL KRT7-AS (but not its non-KRT7-OL regions) promoted GC cell proliferation

12. These data support the theory that CK7 staining may inform risk stratification for low-grade squamous intraepithelial cervical lesions (CIN1).

13. the status of K7 expression in metastatic lymph nodes from colorectal carcinoma is a poor prognostic factor

14. Mismatch repair (MMR) defects influence the expression of clinically important biomarkers for endometrioid-type endometrial carcinoma as decreased cytokeratin 7 expression is more commonly associated with MMR deficiency.

15. Ischemic parenchymal changes are characterized by hepatocyte K7 immunoexpression

16. Survival analysis showed that the non-small cell lung carcinoma patients with enhanced expression of CK7, ELF3, EGFR, and EphB4 mRNA in peripheral blood leukocytes had poorer disease-free survival and overall survival than those without.

17. Immunocytochemistry using this antibody cocktail comprises five antibodies recognising p63, and cytokeratins ( 7, 18, 5 and 14) showed good sensitivity and specificity for diagnosing breast cancers. Thus, this method is useful for mammary cytology using FNA

18. Keratin 34betaE12/K7 expression is a prognostic parameter in resected early stage NSCLC that allows identification of high-risk NSCLC patients with poor cancer-specific and overall survival.

19. K7 expression was also detected in 72 of 75 triple-negative carcinoma cases

20. CK7, TTF-1 and napsin A are predominantly expressed in primary lung adenocarcinoma patients, with CDX-2 being inconsistently expressed.

Mouse (Murine) Keratin 7 (KRT7) interaction partners

1. Keratin-7 deficiency resulted in increased proliferation of the bladder urothelium, although this was not associated with hyperplasia.

2. The -0.25 kb region of keratin 7 promoter showed pancreatic selectivity, high activity in pancreatic cancers, & sustained transgene expression in xenografts. krt7 promoter is useful to target pancreatic ductal adenocarcinoma cells in vitro and in vivo.