Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Proteins (KIR2DL1)

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Antibodies (84) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KIR2DL1 3802 P43626
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Top Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Proteins at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
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Human Cells Human Fc Tag 50 μg 14 to 16 Days
$440.65
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Escherichia coli (E. coli) Human His tag,GST tag 100 μg 15 to 18 Days
$752.00
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Escherichia coli (E. coli) Human Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg 9 to 11 Days
$443.57
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Wheat germ Human Un-conjugated   10 μg 11 to 12 Days
$654.29
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Human Un-conjugated   20 μg 6 Days
$285.21
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KIR2DL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,

More Proteins for Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) Interaction Partners

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) interaction partners

  1. More NK cells educated through KIR2DL1 and KIR3DL1, but not KIR2DL3, responded to antibody-dependent (AD) NK cell activation than their uneducated counterparts.

  2. matching of KIR2DL1, 2DS1, and 2DS2 in donors with their HLA-C ligands in recipients is associated with increased GvHD, and holds potential for selection of HSCT donors.

  3. In a case-control study of pre-eclampsia, the authors show that KIR2DL1A, not KIR2DL1B, associates with increased Pre-Eclampsia disease risk.

  4. Distinguishing these haplotypes are independent mutations in KIR2DL1.

  5. KIR 2D (L1, L3, L4, S4) and KIR 3DL1 expression was correlated with poor prognosis in non-small cell lung carcinoma patients.

  6. A negative association between the KIR2DL1 polymorphism and susceptibility to type 1 diabetes mellitus was found.

  7. the surface organization of paired killer Ig-like receptors (KIR), KIR2DL1 and KIR2DS1, on human primary natural killer cells and cell lines, was examined.

  8. A significantly higher risk of chronic rejection after kidney transplantation was observed when recipient (r) and donor (d) pairs completely lacked the two functional rKIR-dHLA ligand combinations rKIR2DL1/dHLA-C2 and rKIR3DL1/dHLA-Bw4.

  9. CD16+ cells were significantly more frequent among Natural Killer (NK) cells negative for the inhibitory KIR (iKIR) KIR2DL1, KIR2DL3, and KIR3DL1 than those positive for any one of these iKIR to the exclusion of the others, making iKIR+ NK cells poorer antibody dependent cellular cytotoxicity effectors than iKIR- NK cells.

  10. Data indicate that a novel variant allele, KIR2DL1*031, was identified by cDNA cloning and haplotype sequencing of killer cell immunoglobulin-like receptor 2DL1 (KIR2DL1) gene.

  11. KIR2DL1-C2C2 is less frequent in type 1 diabetes in Saudi children

  12. Influence of Differently Licensed KIR2DL1-Positive Natural Killer Cells in Transplant Recipients with Acute Leukemia

  13. Educated natural killer cells expressing KIR2DL1 display functional advantage for anti-HIV-1 antibody-dependent activation.

  14. KIR2DL1*022 and 2DL1*026 evolved in the KhoeSan after their divergence from other modern human populations.

  15. Data suggest regulatory interactions between major histocompatibility antigen HLA-C and killer cell Ig-like receptor (KIR) might promote Graft-versus-Leukemia effects following transplantation.

  16. Coengagement of inhibitory receptors, either KIR2DL1 or CD94-NKG2A, did not inhibit phosphorylation of Stat5 but inhibited selectively phosphorylation of Akt and S6 ribosomal protein.

  17. genetic association studies in Chinese Han population: Data suggest that the frequency of KIR2DL1 gene is increased in women with pre-eclampsia when homozygous HLA-C2 allele appears in the fetus.

  18. Array CGH showed a 95 Kb de novo duplication on chromosome 19q13.4 encompassing four killer cell immunoglobulin-like receptor (KIR) genes.

  19. These results revealed that ITIM phosphorylation is controlled by self-association of KIR and that His-36 serves as a gatekeeper to prevent unregulated signaling through KIR2DL1.

  20. C2 of KIR2DL1 is a novel risk factor, and homozygosity for C1 is a protective factor for childhood B-ALL

Pig (Porcine) Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) interaction partners

  1. using porcine transcriptome data, both the novel inhibitory gene and the LILR were highly expressed in peripheral blood, while the single KIR gene, KIR2DL1, was either very poorly expressed or not at all. These observations are a prerequisite for improved understanding of immune cell functions in the pig and other species.

  2. The first and possibly only KIR gene, named KIR2DL1, in Sus scrofa was identified.

Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) Protein Profile

Protein Summary

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene names and symbols associated with KIR2DL1

  • killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 (KIR2DL1)
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 (KIR2DL1)
  • CD158A protein
  • KIR-K64 protein
  • KIR221 protein
  • NKAT protein
  • NKAT1 protein
  • p58.1 protein

Protein level used designations for KIR2DL1

CD158 antigen-like family member A , MHC class I NK cell receptor , NKAT-1 , killer Ig receptor , killer cell immunoglobulin-like receptor 2DL1 , killer inhibitory receptor 2-2-1 , natural killer-associated transcript 1 , p58 NK cell inhibitory receptor NKR-K6 , p58 NK receptor CL-42/47.11 , p58 killer cell inhibitory receptor KIR-K64 , p58 natural killer cell receptor clones CL-42/47.11 , p58.1 MHC class-I-specific NK receptor

GENE ID SPECIES
3802 Homo sapiens
100127456 Sus scrofa
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